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294 related items for PubMed ID: 20571029

  • 1. Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells.
    Xiao D, Powolny AA, Moura MB, Kelley EE, Bommareddy A, Kim SH, Hahm ER, Normolle D, Van Houten B, Singh SV.
    J Biol Chem; 2010 Aug 20; 285(34):26558-69. PubMed ID: 20571029
    [Abstract] [Full Text] [Related]

  • 2. Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells.
    Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, Jiang Y, Singh SV.
    Cancer Res; 2009 Apr 15; 69(8):3704-12. PubMed ID: 19336571
    [Abstract] [Full Text] [Related]

  • 3. Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.
    Xiao D, Lew KL, Zeng Y, Xiao H, Marynowski SW, Dhir R, Singh SV.
    Carcinogenesis; 2006 Nov 15; 27(11):2223-34. PubMed ID: 16774948
    [Abstract] [Full Text] [Related]

  • 4. p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells.
    Xiao D, Singh SV.
    Cancer Res; 2010 Apr 15; 70(8):3150-8. PubMed ID: 20354186
    [Abstract] [Full Text] [Related]

  • 5. Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration.
    Kim SH, Sehrawat A, Sakao K, Hahm ER, Singh SV.
    PLoS One; 2011 Apr 15; 6(10):e26615. PubMed ID: 22039516
    [Abstract] [Full Text] [Related]

  • 6. Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1.
    Hu J, Straub J, Xiao D, Singh SV, Yang HS, Sonenberg N, Vatsyayan J.
    Cancer Res; 2007 Apr 15; 67(8):3569-73. PubMed ID: 17440067
    [Abstract] [Full Text] [Related]

  • 7. Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.
    Yeh YT, Yeh H, Su SH, Lin JS, Lee KJ, Shyu HW, Chen ZF, Huang SY, Su SJ.
    Free Radic Biol Med; 2014 Sep 15; 74():1-13. PubMed ID: 24952138
    [Abstract] [Full Text] [Related]

  • 8. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D, Johnson CS, Trump DL, Singh SV.
    Mol Cancer Ther; 2004 May 15; 3(5):567-75. PubMed ID: 15141014
    [Abstract] [Full Text] [Related]

  • 9. Bim contributes to phenethyl isothiocyanate-induced apoptosis in breast cancer cells.
    Hahm ER, Singh SV.
    Mol Carcinog; 2012 Jun 15; 51(6):465-74. PubMed ID: 21739479
    [Abstract] [Full Text] [Related]

  • 10. Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases.
    Xiao D, Singh SV.
    Cancer Res; 2002 Jul 01; 62(13):3615-9. PubMed ID: 12097262
    [Abstract] [Full Text] [Related]

  • 11. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, Chou ST, Ma CY, Hsia TC, Ko YC, Chung JG.
    J Orthop Res; 2011 Aug 01; 29(8):1199-209. PubMed ID: 21374707
    [Abstract] [Full Text] [Related]

  • 12. Phenethyl isothiocyanate inhibits growth of human chronic myeloid leukemia K562 cells via reactive oxygen species generation and caspases.
    Wang Y, Wei S, Wang J, Fang Q, Chai Q.
    Mol Med Rep; 2014 Jul 01; 10(1):543-9. PubMed ID: 24788892
    [Abstract] [Full Text] [Related]

  • 13. Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.
    Huang SH, Hsu MH, Hsu SC, Yang JS, Huang WW, Huang AC, Hsiao YP, Yu CC, Chung JG.
    Hum Exp Toxicol; 2014 Mar 01; 33(3):270-83. PubMed ID: 23760257
    [Abstract] [Full Text] [Related]

  • 14. Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells.
    Gong A, He M, Krishna Vanaja D, Yin P, Karnes RJ, Young CY.
    Mol Nutr Food Res; 2009 Jul 01; 53(7):878-86. PubMed ID: 19437484
    [Abstract] [Full Text] [Related]

  • 15. CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells.
    Sakao K, Vyas AR, Chinni SR, Amjad AI, Parikh R, Singh SV.
    Cancer Prev Res (Phila); 2015 May 01; 8(5):365-74. PubMed ID: 25712054
    [Abstract] [Full Text] [Related]

  • 16. Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells.
    Boyanapalli SS, Li W, Fuentes F, Guo Y, Ramirez CN, Gonzalez XP, Pung D, Kong AN.
    Pharmacol Res; 2016 Dec 01; 114():175-184. PubMed ID: 27818231
    [Abstract] [Full Text] [Related]

  • 17. Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer.
    Powolny AA, Bommareddy A, Hahm ER, Normolle DP, Beumer JH, Nelson JB, Singh SV.
    J Natl Cancer Inst; 2011 Apr 06; 103(7):571-84. PubMed ID: 21330634
    [Abstract] [Full Text] [Related]

  • 18. Phenethyl Isothiocyanate Induces Apoptotic Cell Death Through the Mitochondria-dependent Pathway in Gefitinib-resistant NCI-H460 Human Lung Cancer Cells In Vitro.
    Hsia TC, Huang YP, Jiang YW, Chen HY, Cheng ZY, Hsiao YT, Chen CY, Peng SF, Chueh FS, Chou YC, Chung JG.
    Anticancer Res; 2018 Apr 06; 38(4):2137-2147. PubMed ID: 29599332
    [Abstract] [Full Text] [Related]

  • 19. Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanate-mediated changes in expression of antioxidant defense genes.
    Powolny AA, Singh SV.
    Pharm Res; 2010 Dec 06; 27(12):2766-75. PubMed ID: 20872049
    [Abstract] [Full Text] [Related]

  • 20. Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.
    Hahm ER, Moura MB, Kelley EE, Van Houten B, Shiva S, Singh SV.
    PLoS One; 2011 Dec 06; 6(8):e23354. PubMed ID: 21853114
    [Abstract] [Full Text] [Related]

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