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Journal Abstract Search

364 related items for PubMed ID: 20599782

  • 1. The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling.
    Flannery S, Bowie AG.
    Biochem Pharmacol; 2010 Dec 15; 80(12):1981-91. PubMed ID: 20599782
    [Abstract] [Full Text] [Related]

  • 2. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4.
    Suzuki N, Suzuki S, Duncan GS, Millar DG, Wada T, Mirtsos C, Takada H, Wakeham A, Itie A, Li S, Penninger JM, Wesche H, Ohashi PS, Mak TW, Yeh WC.
    Nature; 2002 Apr 18; 416(6882):750-6. PubMed ID: 11923871
    [Abstract] [Full Text] [Related]

  • 3. Toll-like receptor cross-hyporesponsiveness is functional in interleukin-1-receptor-associated kinase-1 (IRAK-1)-deficient macrophages: differential role played by IRAK-1 in regulation of tumour necrosis factor and interleukin-10 production.
    Berglund M, Thomas JA, Hörnquist EH, Hultgren OH.
    Scand J Immunol; 2008 May 18; 67(5):473-9. PubMed ID: 18405325
    [Abstract] [Full Text] [Related]

  • 4. The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation.
    Koziczak-Holbro M, Littlewood-Evans A, Pöllinger B, Kovarik J, Dawson J, Zenke G, Burkhart C, Müller M, Gram H.
    Arthritis Rheum; 2009 Jun 18; 60(6):1661-71. PubMed ID: 19479877
    [Abstract] [Full Text] [Related]

  • 5. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
    Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA.
    Nature; 2001 Sep 06; 413(6851):78-83. PubMed ID: 11544529
    [Abstract] [Full Text] [Related]

  • 6. Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.
    Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S.
    J Exp Med; 2005 Mar 21; 201(6):915-23. PubMed ID: 15767370
    [Abstract] [Full Text] [Related]

  • 7. Insights from vaccinia virus into Toll-like receptor signalling proteins and their regulation by ubiquitin: role of IRAK-2.
    Bowie AG.
    Biochem Soc Trans; 2008 Jun 21; 36(Pt 3):449-52. PubMed ID: 18481979
    [Abstract] [Full Text] [Related]

  • 8. Interleukin receptor-associated kinase-4 deficiency impairs Toll-like receptor-dependent innate antiviral immune responses.
    McDonald DR, Brown D, Bonilla FA, Geha RS.
    J Allergy Clin Immunol; 2006 Dec 21; 118(6):1357-62. PubMed ID: 17157666
    [Abstract] [Full Text] [Related]

  • 9. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.
    Horng T, Barton GM, Flavell RA, Medzhitov R.
    Nature; 2002 Nov 21; 420(6913):329-33. PubMed ID: 12447442
    [Abstract] [Full Text] [Related]

  • 10. The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells.
    Song KW, Talamas FX, Suttmann RT, Olson PS, Barnett JW, Lee SW, Thompson KD, Jin S, Hekmat-Nejad M, Cai TZ, Manning AM, Hill RJ, Wong BR.
    Mol Immunol; 2009 Apr 21; 46(7):1458-66. PubMed ID: 19181383
    [Abstract] [Full Text] [Related]

  • 11. IRAK1: a critical signaling mediator of innate immunity.
    Gottipati S, Rao NL, Fung-Leung WP.
    Cell Signal; 2008 Feb 21; 20(2):269-76. PubMed ID: 17890055
    [Abstract] [Full Text] [Related]

  • 12. IRAK4 in TLR/IL-1R signaling: possible clinical applications.
    Li X.
    Eur J Immunol; 2008 Mar 21; 38(3):614-8. PubMed ID: 18286571
    [Abstract] [Full Text] [Related]

  • 13. Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).
    Wiens M, Korzhev M, Perovic-Ottstadt S, Luthringer B, Brandt D, Klein S, Müller WE.
    Mol Biol Evol; 2007 Mar 21; 24(3):792-804. PubMed ID: 17190971
    [Abstract] [Full Text] [Related]

  • 14. Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.
    Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Saitoh T, Kawai T, Takeuchi O, Akira S.
    Nat Immunol; 2008 Jun 21; 9(6):684-91. PubMed ID: 18438411
    [Abstract] [Full Text] [Related]

  • 15. IRAK-4--a shared NF-kappaB activator in innate and acquired immunity.
    Suzuki N, Saito T.
    Trends Immunol; 2006 Dec 21; 27(12):566-72. PubMed ID: 17046325
    [Abstract] [Full Text] [Related]

  • 16. Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus.
    Lech M, Kantner C, Kulkarni OP, Ryu M, Vlasova E, Heesemann J, Anz D, Endres S, Kobayashi KS, Flavell RA, Martin J, Anders HJ.
    Ann Rheum Dis; 2011 Dec 21; 70(12):2207-17. PubMed ID: 21875872
    [Abstract] [Full Text] [Related]

  • 17. Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator of bone marrow-derived dendritic cells.
    Maekawa Y, Mizue N, Chan A, Shi Y, Liu Y, Dawood S, Chen M, Dawood F, de Couto G, Li GH, Suzuki N, Yeh WC, Gramolini A, Medin JA, Liu PP.
    Circulation; 2009 Oct 06; 120(14):1401-14. PubMed ID: 19770394
    [Abstract] [Full Text] [Related]

  • 18. A novel splice variant of mouse interleukin-1-receptor-associated kinase-1 (IRAK-1) activates nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK).
    Yanagisawa K, Tago K, Hayakawa M, Ohki M, Iwahana H, Tominaga S.
    Biochem J; 2003 Feb 15; 370(Pt 1):159-66. PubMed ID: 12418963
    [Abstract] [Full Text] [Related]

  • 19. Down-regulation of IRAK-4 is a component of LPS- and CpG DNA-induced tolerance in macrophages.
    De Nardo D, Nguyen T, Hamilton JA, Scholz GM.
    Cell Signal; 2009 Feb 15; 21(2):246-52. PubMed ID: 18992325
    [Abstract] [Full Text] [Related]

  • 20. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6.
    Häcker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, Wang GG, Kamps MP, Raz E, Wagner H, Häcker G, Mann M, Karin M.
    Nature; 2006 Jan 12; 439(7073):204-7. PubMed ID: 16306937
    [Abstract] [Full Text] [Related]

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