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Journal Abstract Search
67 related items for PubMed ID: 20619663
1. Rational conversion of noncontinuous active region in proteins into a small orally bioavailable macrocyclic drug-like molecule: the HIV-1 CD4:gp120 paradigm. Hurevich M, Swed A, Joubran S, Cohen S, Freeman NS, Britan-Rosich E, Briant-Longuet L, Bardy M, Devaux C, Kotler M, Hoffman A, Gilon C. Bioorg Med Chem; 2010 Aug 01; 18(15):5754-61. PubMed ID: 20619663 [Abstract] [Full Text] [Related]
2. A dynamic target-based pharmacophoric model mapping the CD4 binding site on HIV-1 gp120 to identify new inhibitors of gp120-CD4 protein-protein interactions. Caporuscio F, Tafi A, González E, Manetti F, Esté JA, Botta M. Bioorg Med Chem Lett; 2009 Nov 01; 19(21):6087-91. PubMed ID: 19783140 [Abstract] [Full Text] [Related]
3. Design, synthesis and evaluation of potential inhibitors of HIV gp120-CD4 interactions. Boussard C, Klimkait T, Mahmood N, Pritchard M, Gilbert IH. Bioorg Med Chem Lett; 2004 May 17; 14(10):2673-6. PubMed ID: 15109676 [Abstract] [Full Text] [Related]
4. Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. Zhao Q, Ma L, Jiang S, Lu H, Liu S, He Y, Strick N, Neamati N, Debnath AK. Virology; 2005 Sep 01; 339(2):213-25. PubMed ID: 15996703 [Abstract] [Full Text] [Related]
9. CD4 mimics targeting the mechanism of HIV entry. Yamada Y, Ochiai C, Yoshimura K, Tanaka T, Ohashi N, Narumi T, Nomura W, Harada S, Matsushita S, Tamamura H. Bioorg Med Chem Lett; 2010 Jan 01; 20(1):354-8. PubMed ID: 19926478 [Abstract] [Full Text] [Related]
10. How can (-)-epigallocatechin gallate from green tea prevent HIV-1 infection? Mechanistic insights from computational modeling and the implication for rational design of anti-HIV-1 entry inhibitors. Hamza A, Zhan CG. J Phys Chem B; 2006 Feb 16; 110(6):2910-7. PubMed ID: 16471901 [Abstract] [Full Text] [Related]
11. Critical role of Arg59 in the high-affinity gp120-binding region of CD4 for human immunodeficiency virus type 1 infection. Fontenot D, Jones JK, Hossain MM, Nehete PN, Vela EM, Dwyer VA, Jagannadha Sastry K. Virology; 2007 Jun 20; 363(1):69-78. PubMed ID: 17320923 [Abstract] [Full Text] [Related]
12. Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction. Williams DH, Adam F, Fenwick DR, Fok-Seang J, Gardner I, Hay D, Jaiessh R, Middleton DS, Mowbray CE, Parkinson T, Perros M, Pickford C, Platts M, Randall A, Siddle D, Stephenson PT, Tran TD, Vuong H. Bioorg Med Chem Lett; 2009 Sep 01; 19(17):5246-9. PubMed ID: 19620004 [Abstract] [Full Text] [Related]
13. Molecular docking guided structure based design of symmetrical N,N'-disubstituted urea/thiourea as HIV-1 gp120-CD4 binding inhibitors. Sivan SK, Vangala R, Manga V. Bioorg Med Chem; 2013 Aug 01; 21(15):4591-9. PubMed ID: 23777826 [Abstract] [Full Text] [Related]
14. Synthetic CD4 exocyclics inhibit binding of human immunodeficiency virus type 1 envelope to CD4 and virus replication in T lymphocytes. Zhang X, Gaubin M, Briant L, Srikantan V, Murali R, Saragovi U, Weiner D, Devaux C, Autiero M, Piatier-Tonneau D, Greene MI. Nat Biotechnol; 1997 Feb 01; 15(2):150-4. PubMed ID: 9035140 [Abstract] [Full Text] [Related]
15. Functional design of potential inhibitors of human immunodeficiency virus (HIV) binding to CD4+ target cells: a molecular model of gp120 predicts ligand binding. Gabriel JL, Mitchell WM. Drug Des Discov; 1996 Oct 01; 14(2):103-14. PubMed ID: 9010617 [Abstract] [Full Text] [Related]
16. Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions. Biorn AC, Cocklin S, Madani N, Si Z, Ivanovic T, Samanen J, Van Ryk DI, Pantophlet R, Burton DR, Freire E, Sodroski J, Chaiken IM. Biochemistry; 2004 Feb 24; 43(7):1928-38. PubMed ID: 14967033 [Abstract] [Full Text] [Related]
17. Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Huang CC, Stricher F, Martin L, Decker JM, Majeed S, Barthe P, Hendrickson WA, Robinson J, Roumestand C, Sodroski J, Wyatt R, Shaw GM, Vita C, Kwong PD. Structure; 2005 May 24; 13(5):755-68. PubMed ID: 15893666 [Abstract] [Full Text] [Related]
18. Molecular modeling on human CCR5 receptors and complex with CD4 antigens and HIV-1 envelope glycoprotein gp120. Yang J, Liu CQ. Acta Pharmacol Sin; 2000 Jan 24; 21(1):29-34. PubMed ID: 11263244 [Abstract] [Full Text] [Related]
19. Identification of putative, stable binding regions through flexibility analysis of HIV-1 gp120. Tan H, Rader AJ. Proteins; 2009 Mar 24; 74(4):881-94. PubMed ID: 18704932 [Abstract] [Full Text] [Related]
20. Synthetic mimetics of the CD4 binding site of HIV-1 gp120 for the design of immunogens. Franke R, Hirsch T, Overwin H, Eichler J. Angew Chem Int Ed Engl; 2007 Mar 24; 46(8):1253-5. PubMed ID: 17211914 [No Abstract] [Full Text] [Related] Page: [Next] [New Search]