These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Integrated comparison of drug-related and drug-induced ultra performance liquid chromatography/mass spectrometry metabonomic profiles using human hepatocyte cultures. Croixmarie V, Umbdenstock T, Cloarec O, Moreau A, Pascussi JM, Boursier-Neyret C, Walther B. Anal Chem; 2009 Aug 01; 81(15):6061-9. PubMed ID: 19588937 [Abstract] [Full Text] [Related]
3. Regulation of gender-dependent CYP2A expression in pigs: involvement of androgens and CAR. Gillberg M, Skaanild MT, Friis C. Basic Clin Pharmacol Toxicol; 2006 May 01; 98(5):480-7. PubMed ID: 16635107 [Abstract] [Full Text] [Related]
4. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes. Kandel BA, Thomas M, Winter S, Damm G, Seehofer D, Burk O, Schwab M, Zanger UM. Biochim Biophys Acta; 2016 Sep 01; 1859(9):1218-1227. PubMed ID: 26994748 [Abstract] [Full Text] [Related]
5. Induction of CYP2C genes in human hepatocytes in primary culture. Gerbal-Chaloin S, Pascussi JM, Pichard-Garcia L, Daujat M, Waechter F, Fabre JM, Carrère N, Maurel P. Drug Metab Dispos; 2001 Mar 01; 29(3):242-51. PubMed ID: 11181490 [Abstract] [Full Text] [Related]
6. Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor. de Boussac H, Gondeau C, Briolotti P, Duret C, Treindl F, Römer M, Fabre JM, Herrero A, Ramos J, Maurel P, Templin M, Gerbal-Chaloin S, Daujat-Chavanieu M. Drug Metab Dispos; 2018 Mar 01; 46(3):223-236. PubMed ID: 29269410 [Abstract] [Full Text] [Related]
7. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression. Roth A, Looser R, Kaufmann M, Blättler SM, Rencurel F, Huang W, Moore DD, Meyer UA. Mol Pharmacol; 2008 Apr 01; 73(4):1282-9. PubMed ID: 18187584 [Abstract] [Full Text] [Related]
8. Lack of P-glycoprotein induction by rifampicin and phenobarbital in human lymphocytes. Manceau S, Giraud C, Declèves X, Batteux F, Chouzenoux S, Tang R, Dauchy S, Scherrmann JM, Weill B, Morini JP, Perrot JY, Tréluyer JM. Int J Pharm; 2010 Aug 16; 395(1-2):98-103. PubMed ID: 20488228 [Abstract] [Full Text] [Related]
9. Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation. Soldatow V, Peffer RC, Trask OJ, Cowie DE, Andersen ME, LeCluyse E, Deisenroth C. Toxicol In Vitro; 2016 Oct 16; 36():224-237. PubMed ID: 27530964 [Abstract] [Full Text] [Related]
10. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. J Biol Chem; 2003 May 09; 278(19):17277-83. PubMed ID: 12611900 [Abstract] [Full Text] [Related]
11. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor. Wyde ME, Bartolucci E, Ueda A, Zhang H, Yan B, Negishi M, You L. Mol Pharmacol; 2003 Aug 09; 64(2):474-81. PubMed ID: 12869653 [Abstract] [Full Text] [Related]
12. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes. Dvorák Z, Maurel P, Vilarem MJ, Ulrichová J, Modrianský M. Cell Biol Toxicol; 2007 Mar 09; 23(2):63-73. PubMed ID: 16964586 [Abstract] [Full Text] [Related]
13. Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor. Chen Y, Ferguson SS, Negishi M, Goldstein JA. J Pharmacol Exp Ther; 2004 Feb 09; 308(2):495-501. PubMed ID: 14600250 [Abstract] [Full Text] [Related]
14. Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver. Guo D, Sarkar J, Ahmed MR, Viswakarma N, Jia Y, Yu S, Sambasiva Rao M, Reddy JK. Biochem Biophys Res Commun; 2006 Aug 25; 347(2):485-95. PubMed ID: 16828057 [Abstract] [Full Text] [Related]
15. CITCO Directly Binds to and Activates Human Pregnane X Receptor. Lin W, Bwayi M, Wu J, Li Y, Chai SC, Huber AD, Chen T. Mol Pharmacol; 2020 Mar 25; 97(3):180-190. PubMed ID: 31882411 [Abstract] [Full Text] [Related]
16. Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells. Li D, Mackowiak B, Brayman TG, Mitchell M, Zhang L, Huang SM, Wang H. Biochem Pharmacol; 2015 Nov 01; 98(1):190-202. PubMed ID: 26275810 [Abstract] [Full Text] [Related]
17. Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor. Lau AJ, Yang G, Rajaraman G, Baucom CC, Chang TK. J Pharmacol Exp Ther; 2011 Mar 01; 336(3):816-26. PubMed ID: 21131266 [Abstract] [Full Text] [Related]
18. CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs. Chirulli V, Longo V, Marini S, Mazzaccaro A, Fiorio R, Gervasi PG. Life Sci; 2005 Apr 15; 76(22):2535-46. PubMed ID: 15769478 [Abstract] [Full Text] [Related]
19. Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes. Pascussi JM, Gerbal-Chaloin S, Pichard-Garcia L, Daujat M, Fabre JM, Maurel P, Vilarem MJ. Biochem Biophys Res Commun; 2000 Aug 11; 274(3):707-13. PubMed ID: 10924340 [Abstract] [Full Text] [Related]
20. Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells. Anthérieu S, Chesné C, Li R, Camus S, Lahoz A, Picazo L, Turpeinen M, Tolonen A, Uusitalo J, Guguen-Guillouzo C, Guillouzo A. Drug Metab Dispos; 2010 Mar 11; 38(3):516-25. PubMed ID: 20019244 [Abstract] [Full Text] [Related] Page: [Next] [New Search]