These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

240 related items for PubMed ID: 20663861

  • 1. Nitric oxide inhibits the proliferation and invasion of pancreatic cancer cells through degradation of insulin receptor substrate-1 protein.
    Sugita H, Kaneki M, Furuhashi S, Hirota M, Takamori H, Baba H.
    Mol Cancer Res; 2010 Aug; 8(8):1152-63. PubMed ID: 20663861
    [Abstract] [Full Text] [Related]

  • 2. Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.
    Tanioka T, Tamura Y, Fukaya M, Shinozaki S, Mao J, Kim M, Shimizu N, Kitamura T, Kaneki M.
    J Biol Chem; 2011 Aug 19; 286(33):29388-29396. PubMed ID: 21700708
    [Abstract] [Full Text] [Related]

  • 3. Insulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3β to regulate aerobic glycolysis.
    Landis J, Shaw LM.
    J Biol Chem; 2014 Jun 27; 289(26):18603-13. PubMed ID: 24811175
    [Abstract] [Full Text] [Related]

  • 4. NO donor and MEK inhibitor synergistically inhibit proliferation and invasion of cancer cells.
    Furuhashi S, Sugita H, Takamori H, Horino K, Nakahara O, Okabe H, Miyake K, Tanaka H, Beppu T, Baba H.
    Int J Oncol; 2012 Mar 27; 40(3):807-15. PubMed ID: 22025280
    [Abstract] [Full Text] [Related]

  • 5. Progesterone receptor-B regulation of insulin-like growth factor-stimulated cell migration in breast cancer cells via insulin receptor substrate-2.
    Ibrahim YH, Byron SA, Cui X, Lee AV, Yee D.
    Mol Cancer Res; 2008 Sep 27; 6(9):1491-8. PubMed ID: 18819936
    [Abstract] [Full Text] [Related]

  • 6. Platelet-derived growth factor negatively regulates the insulin-like growth factor signaling pathway through the coordinated action of phosphatidylinositol 3-kinase and protein kinase C beta I.
    Lassarre C, Legay C, Karam M, Ricort JM.
    Biochim Biophys Acta; 2013 Jun 27; 1833(6):1367-77. PubMed ID: 23481042
    [Abstract] [Full Text] [Related]

  • 7. IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma.
    Gao L, Wang X, Wang X, Zhang L, Qiang C, Chang S, Ren W, Li S, Yang Y, Tong D, Chen C, Li Z, Song T, Zhi K, Huang C.
    Oncotarget; 2014 May 15; 5(9):2562-74. PubMed ID: 24810113
    [Abstract] [Full Text] [Related]

  • 8. Overexpression of Akt1 upregulates glycogen synthase activity and phosphorylation of mTOR in IRS-1 knockdown HepG2 cells.
    Varma S, Khandelwal RL.
    J Cell Biochem; 2008 Apr 01; 103(5):1424-37. PubMed ID: 17721885
    [Abstract] [Full Text] [Related]

  • 9. Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells.
    Cahuana GM, Tejedo JR, Hmadcha A, Ramírez R, Cuesta AL, Soria B, Martin F, Bedoya FJ.
    Cell Signal; 2008 Feb 01; 20(2):301-10. PubMed ID: 18023142
    [Abstract] [Full Text] [Related]

  • 10. Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells.
    Sugita H, Fujimoto M, Yasukawa T, Shimizu N, Sugita M, Yasuhara S, Martyn JA, Kaneki M.
    J Biol Chem; 2005 Apr 08; 280(14):14203-11. PubMed ID: 15805118
    [Abstract] [Full Text] [Related]

  • 11. AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation.
    Ning J, Clemmons DR.
    Mol Endocrinol; 2010 Jun 08; 24(6):1218-29. PubMed ID: 20363874
    [Abstract] [Full Text] [Related]

  • 12. Proteasomal degradation of IRS-2, but not IRS-1 by calcineurin inhibition: attenuation of insulin-like growth factor-I-induced GSK-3beta and ERK pathways in adrenal chromaffin cells.
    Satoh S, Yanagita T, Maruta T, Nemoto T, Yoshikawa N, Kobayashi H, Tono T, Wada A.
    Neuropharmacology; 2008 Jul 08; 55(1):71-9. PubMed ID: 18538359
    [Abstract] [Full Text] [Related]

  • 13. Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.
    Rui L, Fisher TL, Thomas J, White MF.
    J Biol Chem; 2001 Oct 26; 276(43):40362-7. PubMed ID: 11546773
    [Abstract] [Full Text] [Related]

  • 14. Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
    Andreozzi F, Laratta E, Sciacqua A, Perticone F, Sesti G.
    Circ Res; 2004 May 14; 94(9):1211-8. PubMed ID: 15044323
    [Abstract] [Full Text] [Related]

  • 15. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
    Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.
    Diabetes; 2002 Apr 14; 51(4):966-76. PubMed ID: 11916914
    [Abstract] [Full Text] [Related]

  • 16. The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1.
    Yu W, Singh R, Wang Z, O'Malley BW, Yi P.
    J Biol Chem; 2021 Apr 14; 296():100739. PubMed ID: 33991522
    [Abstract] [Full Text] [Related]

  • 17. IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF-1/PI3K/Akt signaling pathway in pancreatic cancer cells.
    Ma J, Sawai H, Matsuo Y, Ochi N, Yasuda A, Takahashi H, Wakasugi T, Funahashi H, Sato M, Takeyama H.
    J Surg Res; 2010 May 01; 160(1):90-101. PubMed ID: 19560785
    [Abstract] [Full Text] [Related]

  • 18. Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity.
    Mima A, Ohshiro Y, Kitada M, Matsumoto M, Geraldes P, Li C, Li Q, White GS, Cahill C, Rask-Madsen C, King GL.
    Kidney Int; 2011 Apr 01; 79(8):883-96. PubMed ID: 21228767
    [Abstract] [Full Text] [Related]

  • 19. Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling.
    Laviola L, Perrini S, Belsanti G, Natalicchio A, Montrone C, Leonardini A, Vimercati A, Scioscia M, Selvaggi L, Giorgino R, Greco P, Giorgino F.
    Endocrinology; 2005 Mar 01; 146(3):1498-505. PubMed ID: 15564321
    [Abstract] [Full Text] [Related]

  • 20. Mono- or dual-phosphorylation of akt kinase is regulated by distinct receptors that involve the common insulin receptor substrate.
    Schnyder B, Lahm H, Pittet M, Schnyder-Candrian S.
    J Recept Signal Transduct Res; 2002 Mar 01; 22(1-4):213-28. PubMed ID: 12503617
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 12.