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240 related items for PubMed ID: 20663861

  • 21. Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells.
    Stöhr O, Hahn J, Moll L, Leeser U, Freude S, Bernard C, Schilbach K, Markl A, Udelhoven M, Krone W, Schubert M.
    Biochim Biophys Acta; 2011 May; 1812(5):573-80. PubMed ID: 21354306
    [Abstract] [Full Text] [Related]

  • 22. Abnormalities of insulin-like growth factor-I signaling and impaired cell proliferation in osteoblasts from subjects with osteoporosis.
    Perrini S, Natalicchio A, Laviola L, Cignarelli A, Melchiorre M, De Stefano F, Caccioppoli C, Leonardini A, Martemucci S, Belsanti G, Miccoli S, Ciampolillo A, Corrado A, Cantatore FP, Giorgino R, Giorgino F.
    Endocrinology; 2008 Mar; 149(3):1302-13. PubMed ID: 18079194
    [Abstract] [Full Text] [Related]

  • 23. Involvement of insulin-like growth factor type 1 receptor and protein kinase Cdelta in bis(maltolato)oxovanadium(IV)-induced phosphorylation of protein kinase B in HepG2 cells.
    Mehdi MZ, Vardatsikos G, Pandey SK, Srivastava AK.
    Biochemistry; 2006 Sep 26; 45(38):11605-15. PubMed ID: 16981720
    [Abstract] [Full Text] [Related]

  • 24. Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.
    Radhakrishnan Y, Busby WH, Shen X, Maile LA, Clemmons DR.
    J Biol Chem; 2010 May 21; 285(21):15682-95. PubMed ID: 20207740
    [Abstract] [Full Text] [Related]

  • 25. Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats.
    Nemoto S, Kobayashi T, Taguchi K, Matsumoto T, Kamata K.
    Am J Physiol Heart Circ Physiol; 2011 Dec 21; 301(6):H2383-94. PubMed ID: 21926342
    [Abstract] [Full Text] [Related]

  • 26. Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation.
    Fukushima T, Nakamura Y, Yamanaka D, Shibano T, Chida K, Minami S, Asano T, Hakuno F, Takahashi S.
    J Biol Chem; 2012 Aug 24; 287(35):29713-21. PubMed ID: 22767591
    [Abstract] [Full Text] [Related]

  • 27. Focal adhesion kinase mediates cell survival via NF-kappaB and ERK signaling pathways.
    Huang D, Khoe M, Befekadu M, Chung S, Takata Y, Ilic D, Bryer-Ash M.
    Am J Physiol Cell Physiol; 2007 Apr 24; 292(4):C1339-52. PubMed ID: 17135301
    [Abstract] [Full Text] [Related]

  • 28. GSK3 protein positively regulates type I insulin-like growth factor receptor through forkhead transcription factors FOXO1/3/4.
    Huo X, Liu S, Shao T, Hua H, Kong Q, Wang J, Luo T, Jiang Y.
    J Biol Chem; 2014 Sep 05; 289(36):24759-70. PubMed ID: 25053419
    [Abstract] [Full Text] [Related]

  • 29. Insulin-like growth factor binding protein-4 and -5 modulate ligand-dependent estrogen receptor-α activation in breast cancer cells in an IGF-independent manner.
    Hermani A, Shukla A, Medunjanin S, Werner H, Mayer D.
    Cell Signal; 2013 Jun 05; 25(6):1395-402. PubMed ID: 23499909
    [Abstract] [Full Text] [Related]

  • 30. Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling.
    Liberman Z, Eldar-Finkelman H.
    J Biol Chem; 2005 Feb 11; 280(6):4422-8. PubMed ID: 15574412
    [Abstract] [Full Text] [Related]

  • 31. Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis.
    Parvaiz F, Manzoor S, Iqbal J, Sarkar-Dutta M, Imran M, Waris G.
    World J Gastroenterol; 2015 Nov 21; 21(43):12361-9. PubMed ID: 26604643
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  • 32. Proteomic identification of 14-3-3zeta as an adapter for IGF-1 and Akt/GSK-3beta signaling and survival of renal mesangial cells.
    Singh LP, Jiang Y, Cheng DW.
    Int J Biol Sci; 2006 Oct 27; 3(1):27-39. PubMed ID: 17200689
    [Abstract] [Full Text] [Related]

  • 33. Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts.
    Hakuno F, Yamauchi Y, Kaneko G, Yoneyama Y, Nakae J, Chida K, Kadowaki T, Yamanouchi K, Nishihara M, Takahashi S.
    PLoS One; 2011 Oct 27; 6(10):e25655. PubMed ID: 21991327
    [Abstract] [Full Text] [Related]

  • 34. G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells.
    Federici M, Pandolfi A, De Filippis EA, Pellegrini G, Menghini R, Lauro D, Cardellini M, Romano M, Sesti G, Lauro R, Consoli A.
    Circulation; 2004 Jan 27; 109(3):399-405. PubMed ID: 14707024
    [Abstract] [Full Text] [Related]

  • 35. High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phosphorylation in human aortic endothelial cells.
    Salt IP, Morrow VA, Brandie FM, Connell JM, Petrie JR.
    J Biol Chem; 2003 May 23; 278(21):18791-7. PubMed ID: 12644458
    [Abstract] [Full Text] [Related]

  • 36. Inducible nitric oxide synthase deficiency ameliorates skeletal muscle insulin resistance but does not alter unexpected lower blood glucose levels after burn injury in C57BL/6 mice.
    Sugita M, Sugita H, Kim M, Mao J, Yasuda Y, Habiro M, Shinozaki S, Yasuhara S, Shimizu N, Martyn JA, Kaneki M.
    Metabolism; 2012 Jan 23; 61(1):127-36. PubMed ID: 21816442
    [Abstract] [Full Text] [Related]

  • 37. Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways.
    Yin W, Park JI, Loeser RF.
    J Biol Chem; 2009 Nov 13; 284(46):31972-81. PubMed ID: 19762915
    [Abstract] [Full Text] [Related]

  • 38. Enhancement of insulin-induced PI3K/Akt/GSK-3beta and ERK signaling by neuronal nicotinic receptor/PKC-alpha/ERK pathway: up-regulation of IRS-1/-2 mRNA and protein in adrenal chromaffin cells.
    Sugano T, Yanagita T, Yokoo H, Satoh S, Kobayashi H, Wada A.
    J Neurochem; 2006 Jul 13; 98(1):20-33. PubMed ID: 16805793
    [Abstract] [Full Text] [Related]

  • 39. The reciprocal regulation of gamma-synuclein and IGF-I receptor expression creates a circuit that modulates IGF-I signaling.
    Li M, Yin Y, Hua H, Sun X, Luo T, Wang J, Jiang Y.
    J Biol Chem; 2010 Oct 01; 285(40):30480-8. PubMed ID: 20670935
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  • 40. Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells.
    Karnevi E, Said K, Andersson R, Rosendahl AH.
    BMC Cancer; 2013 May 10; 13():235. PubMed ID: 23663483
    [Abstract] [Full Text] [Related]

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