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185 related items for PubMed ID: 20664534

  • 1. Grapefruit juice greatly reduces the plasma concentrations of the OATP2B1 and CYP3A4 substrate aliskiren.
    Tapaninen T, Neuvonen PJ, Niemi M.
    Clin Pharmacol Ther; 2010 Sep; 88(3):339-42. PubMed ID: 20664534
    [Abstract] [Full Text] [Related]

  • 2. Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.
    Rebello S, Zhao S, Hariry S, Dahlke M, Alexander N, Vapurcuyan A, Hanna I, Jarugula V.
    Eur J Clin Pharmacol; 2012 May; 68(5):697-708. PubMed ID: 22124880
    [Abstract] [Full Text] [Related]

  • 3. Itraconazole, a P-glycoprotein and CYP3A4 inhibitor, markedly raises the plasma concentrations and enhances the renin-inhibiting effect of aliskiren.
    Tapaninen T, Backman JT, Kurkinen KJ, Neuvonen PJ, Niemi M.
    J Clin Pharmacol; 2011 Mar; 51(3):359-67. PubMed ID: 20400651
    [Abstract] [Full Text] [Related]

  • 4. Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren.
    Tapaninen T, Neuvonen PJ, Niemi M.
    Br J Clin Pharmacol; 2011 May; 71(5):718-26. PubMed ID: 21204914
    [Abstract] [Full Text] [Related]

  • 5. SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.
    Tapaninen T, Karonen T, Backman JT, Neuvonen PJ, Niemi M.
    Pharmacogenet Genomics; 2013 Jan; 23(1):19-24. PubMed ID: 23151832
    [Abstract] [Full Text] [Related]

  • 6. Grapefruit juice enhances the exposure to oral oxycodone.
    Nieminen TH, Hagelberg NM, Saari TI, Neuvonen M, Neuvonen PJ, Laine K, Olkkola KT.
    Basic Clin Pharmacol Toxicol; 2010 Oct; 107(4):782-8. PubMed ID: 20406214
    [Abstract] [Full Text] [Related]

  • 7. Grapefruit juice markedly increases the plasma concentrations and antiplatelet effects of ticagrelor in healthy subjects.
    Holmberg MT, Tornio A, Joutsi-Korhonen L, Neuvonen M, Neuvonen PJ, Lassila R, Niemi M, Backman JT.
    Br J Clin Pharmacol; 2013 Jun; 75(6):1488-96. PubMed ID: 23126367
    [Abstract] [Full Text] [Related]

  • 8. Grapefruit juice inhibits the metabolic activation of clopidogrel.
    Holmberg MT, Tornio A, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M.
    Clin Pharmacol Ther; 2014 Mar; 95(3):307-13. PubMed ID: 24067745
    [Abstract] [Full Text] [Related]

  • 9. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.
    Bailey DG, Dresser GK, Bend JR.
    Clin Pharmacol Ther; 2003 Jun; 73(6):529-37. PubMed ID: 12811362
    [Abstract] [Full Text] [Related]

  • 10. Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin.
    Lilja JJ, Kivistö KT, Neuvonen PJ.
    Clin Pharmacol Ther; 2000 Oct; 68(4):384-90. PubMed ID: 11061578
    [Abstract] [Full Text] [Related]

  • 11. Effect of grapefruit juice on the bioactivation of prasugrel.
    Holmberg MT, Tornio A, Hyvärinen H, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M.
    Br J Clin Pharmacol; 2015 Jul; 80(1):139-45. PubMed ID: 25557052
    [Abstract] [Full Text] [Related]

  • 12. Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid.
    Kantola T, Kivistö KT, Neuvonen PJ.
    Clin Pharmacol Ther; 1998 Apr; 63(4):397-402. PubMed ID: 9585793
    [Abstract] [Full Text] [Related]

  • 13. A study of dose-proportionality in the pharmacokinetics of the oral direct renin inhibitor aliskiren in healthy subjects.
    Limoges D, Dieterich HA, Yeh CM, Vaidyanathan S, Howard D, Dole WP.
    Int J Clin Pharmacol Ther; 2008 May; 46(5):252-8. PubMed ID: 18538111
    [Abstract] [Full Text] [Related]

  • 14. Effect of cyclosporine on the pharmacokinetics of aliskiren in healthy subjects.
    Rebello S, Compain S, Feng A, Hariry S, Dieterich HA, Jarugula V.
    J Clin Pharmacol; 2011 Nov; 51(11):1549-60. PubMed ID: 21406600
    [Abstract] [Full Text] [Related]

  • 15. Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren.
    Vaidyanathan S, Camenisch G, Schuetz H, Reynolds C, Yeh CM, Bizot MN, Dieterich HA, Howard D, Dole WP.
    J Clin Pharmacol; 2008 Nov; 48(11):1323-38. PubMed ID: 18784280
    [Abstract] [Full Text] [Related]

  • 16. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.
    Bailey DG, Dresser GK, Leake BF, Kim RB.
    Clin Pharmacol Ther; 2007 Apr; 81(4):495-502. PubMed ID: 17301733
    [Abstract] [Full Text] [Related]

  • 17. Comparison of inhibitory duration of grapefruit juice on organic anion-transporting polypeptide and cytochrome P450 3A4.
    Tanaka S, Uchida S, Miyakawa S, Inui N, Takeuchi K, Watanabe H, Namiki N.
    Biol Pharm Bull; 2013 Apr; 36(12):1936-41. PubMed ID: 24292052
    [Abstract] [Full Text] [Related]

  • 18. S-ketamine concentrations are greatly increased by grapefruit juice.
    Peltoniemi MA, Saari TI, Hagelberg NM, Laine K, Neuvonen PJ, Olkkola KT.
    Eur J Clin Pharmacol; 2012 Jun; 68(6):979-86. PubMed ID: 22286159
    [Abstract] [Full Text] [Related]

  • 19. Pharmacokinetics, safety and tolerability of single and multiple oral doses of aliskiren in healthy Chinese subjects: a randomized, single-blind, parallel-group, placebo-controlled study.
    Hu P, Bartlett M, Karan RS, Jiang J, Zhang S, Zhang J, Howard D, Yeh CM, Al-Fayoumi S, Jarugula V, Dole WP.
    Clin Drug Investig; 2010 Jun; 30(4):221-8. PubMed ID: 20192280
    [Abstract] [Full Text] [Related]

  • 20. Further characterization of a furanocoumarin-free grapefruit juice on drug disposition: studies with cyclosporine.
    Paine MF, Widmer WW, Pusek SN, Beavers KL, Criss AB, Snyder J, Watkins PB.
    Am J Clin Nutr; 2008 Apr; 87(4):863-71. PubMed ID: 18400708
    [Abstract] [Full Text] [Related]


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