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53 related items for PubMed ID: 20689131

  • 1. Morphoproteomics demonstrates activation of mTOR pathway in anaplastic thyroid carcinoma: a preliminary observation.
    Liu J, Brown RE.
    Ann Clin Lab Sci; 2010; 40(3):211-7. PubMed ID: 20689131
    [Abstract] [Full Text] [Related]

  • 2. The rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Akt-mTOR-p70S6K pathway in human medullary thyroid carcinoma cells.
    Grozinsky-Glasberg S, Rubinfeld H, Nordenberg Y, Gorshtein A, Praiss M, Kendler E, Feinmesser R, Grossman AB, Shimon I.
    Mol Cell Endocrinol; 2010 Feb 05; 315(1-2):87-94. PubMed ID: 19815051
    [Abstract] [Full Text] [Related]

  • 3. Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.
    Feng W, Brown RE, Trung CD, Li W, Wang L, Khoury T, Alrawi S, Yao J, Xia K, Tan D.
    Ann Clin Lab Sci; 2008 Feb 05; 38(3):195-209. PubMed ID: 18715846
    [Abstract] [Full Text] [Related]

  • 4. The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.
    Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2010 Jan 05; 51(1):421-9. PubMed ID: 19661225
    [Abstract] [Full Text] [Related]

  • 5. Morphoproteomic and molecular concomitants of an overexpressed and activated mTOR pathway in renal cell carcinomas.
    Lin F, Zhang PL, Yang XJ, Prichard JW, Lun M, Brown RE.
    Ann Clin Lab Sci; 2006 Jan 05; 36(3):283-93. PubMed ID: 16951269
    [Abstract] [Full Text] [Related]

  • 6. Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.
    Markova B, Albers C, Breitenbuecher F, Melo JV, Brümmendorf TH, Heidel F, Lipka D, Duyster J, Huber C, Fischer T.
    Oncogene; 2010 Feb 04; 29(5):739-51. PubMed ID: 19881535
    [Abstract] [Full Text] [Related]

  • 7. Morphoproteomic and pharmacoproteomic rationale for mTOR effectors as therapeutic targets in head and neck squamous cell carcinoma.
    Brown RE, Zhang PL, Lun M, Zhu S, Pellitteri PK, Riefkohl W, Law A, Wood GC, Kennedy TL.
    Ann Clin Lab Sci; 2006 Feb 04; 36(3):273-82. PubMed ID: 16951268
    [Abstract] [Full Text] [Related]

  • 8. Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma.
    Li W, Tan D, Zhang Z, Liang JJ, Brown RE.
    Oncol Rep; 2008 Oct 04; 20(4):713-9. PubMed ID: 18813808
    [Abstract] [Full Text] [Related]

  • 9. Serine 2481-autophosphorylation of mammalian target of rapamycin (mTOR) couples with chromosome condensation and segregation during mitosis: confocal microscopy characterization and immunohistochemical validation of PP-mTOR(Ser2481) as a novel high-contrast mitosis marker in breast cancer core biopsies.
    Lopez-Bonet E, Vazquez-Martin A, Pérez-Martínez MC, Oliveras-Ferraros C, Pérez-Bueno F, Bernadó L, Menendez JA.
    Int J Oncol; 2010 Jan 04; 36(1):107-15. PubMed ID: 19956839
    [Abstract] [Full Text] [Related]

  • 10. Activation of the mammalian target of rapamycin signalling pathway in prostate cancer and its association with patient clinicopathological characteristics.
    Dai B, Kong YY, Ye DW, Ma CG, Zhou X, Yao XD.
    BJU Int; 2009 Oct 04; 104(7):1009-16. PubMed ID: 19389013
    [Abstract] [Full Text] [Related]

  • 11. Morphoproteomics demonstrates activation of mammalian target of rapamycin pathway in papillary thyroid carcinomas with nuclear translocation of MTOR in aggressive histological variants.
    Liu J, Brown RE.
    Mod Pathol; 2011 Dec 04; 24(12):1553-9. PubMed ID: 21822208
    [Abstract] [Full Text] [Related]

  • 12. Activation of the mTOR pathway in primary medullary thyroid carcinoma and lymph node metastases.
    Tamburrino A, Molinolo AA, Salerno P, Chernock RD, Raffeld M, Xi L, Gutkind JS, Moley JF, Wells SA, Santoro M.
    Clin Cancer Res; 2012 Jul 01; 18(13):3532-40. PubMed ID: 22753663
    [Abstract] [Full Text] [Related]

  • 13. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX, Yang X, Sreejayan N, Ren J.
    Exp Neurol; 2007 Jan 01; 203(1):196-204. PubMed ID: 16962100
    [Abstract] [Full Text] [Related]

  • 14. High glucose regulates cyclin D1/E of human mesenchymal stem cells through TGF-beta1 expression via Ca2+/PKC/MAPKs and PI3K/Akt/mTOR signal pathways.
    Ryu JM, Lee MY, Yun SP, Han HJ.
    J Cell Physiol; 2010 Jul 01; 224(1):59-70. PubMed ID: 20232305
    [Abstract] [Full Text] [Related]

  • 15. Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins.
    Xu Y, Chen SY, Ross KN, Balk SP.
    Cancer Res; 2006 Aug 01; 66(15):7783-92. PubMed ID: 16885382
    [Abstract] [Full Text] [Related]

  • 16. Critical and diverse involvement of Akt/mammalian target of rapamycin signaling in human lung carcinomas.
    Dobashi Y, Suzuki S, Matsubara H, Kimura M, Endo S, Ooi A.
    Cancer; 2009 Jan 01; 115(1):107-18. PubMed ID: 19090006
    [Abstract] [Full Text] [Related]

  • 17. Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer.
    Chiappetta G, De Marco C, Quintiero A, Califano D, Gherardi S, Malanga D, Scrima M, Montero-Conde C, Cito L, Monaco M, Motti ML, Pasquinelli R, Agosti V, Robledo M, Fusco A, Viglietto G.
    Endocr Relat Cancer; 2007 Jun 01; 14(2):405-20. PubMed ID: 17639054
    [Abstract] [Full Text] [Related]

  • 18. Constitutive activation with overexpression of the mTORC2-phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications.
    Dhingra S, Rodriguez ME, Shen Q, Duan X, Stanton ML, Chen L, Zhang R, Brown RE.
    Int J Clin Exp Pathol; 2010 Jan 28; 4(2):134-46. PubMed ID: 21326806
    [Abstract] [Full Text] [Related]

  • 19. Phosphatidylinositol-3 kinase/Akt/p70S6K/AP-1 signaling pathway mediated benzo(a)pyrene-induced cell cycle alternation via cell cycle regulatory proteins in human embryo lung fibroblasts.
    Gao A, Liu B, Shi X, Jia X, Ye M, Jiao S, You B, Huang C.
    Toxicol Lett; 2007 Apr 05; 170(1):30-41. PubMed ID: 17383120
    [Abstract] [Full Text] [Related]

  • 20. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.
    Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS.
    Cancer Res; 2005 Nov 01; 65(21):9953-61. PubMed ID: 16267020
    [Abstract] [Full Text] [Related]

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