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PUBMED FOR HANDHELDS

Journal Abstract Search


387 related items for PubMed ID: 20694684

  • 1. X-ray crystallography in drug discovery.
    Carvalho AL, Trincão J, Romão MJ.
    Methods Mol Biol; 2009; 572():31-56. PubMed ID: 20694684
    [Abstract] [Full Text] [Related]

  • 2. The utility of structural biology in drug discovery.
    Tari LW.
    Methods Mol Biol; 2012; 841():1-27. PubMed ID: 22222446
    [Abstract] [Full Text] [Related]

  • 3. Crystallization to obtain protein-ligand complexes for structure-aided drug design.
    Danley DE.
    Acta Crystallogr D Biol Crystallogr; 2006 Jun; 62(Pt 6):569-75. PubMed ID: 16699182
    [Abstract] [Full Text] [Related]

  • 4. High-throughput protein crystallography and drug discovery.
    Tickle I, Sharff A, Vinkovic M, Yon J, Jhoti H.
    Chem Soc Rev; 2004 Oct 20; 33(8):558-65. PubMed ID: 15480479
    [Abstract] [Full Text] [Related]

  • 5. Recent progress in robot-based systems for crystallography and their contribution to drug discovery.
    Ferrer JL, Larive NA, Bowler MW, Nurizzo D.
    Expert Opin Drug Discov; 2013 Jul 20; 8(7):835-47. PubMed ID: 23656378
    [Abstract] [Full Text] [Related]

  • 6. High-throughput X-ray crystallography for drug discovery.
    Blundell TL, Patel S.
    Curr Opin Pharmacol; 2004 Oct 20; 4(5):490-6. PubMed ID: 15351354
    [Abstract] [Full Text] [Related]

  • 7. Essential considerations for using protein-ligand structures in drug discovery.
    Warren GL, Do TD, Kelley BP, Nicholls A, Warren SD.
    Drug Discov Today; 2012 Dec 20; 17(23-24):1270-81. PubMed ID: 22728777
    [Abstract] [Full Text] [Related]

  • 8. Tautomer preference in PDB complexes and its impact on structure-based drug discovery.
    Milletti F, Vulpetti A.
    J Chem Inf Model; 2010 Jun 28; 50(6):1062-74. PubMed ID: 20515065
    [Abstract] [Full Text] [Related]

  • 9. Key factors for successful generation of protein-fragment structures requirement on protein, crystals, and technology.
    Böttcher J, Jestel A, Kiefersauer R, Krapp S, Nagel S, Steinbacher S, Steuber H.
    Methods Enzymol; 2011 Jun 28; 493():61-89. PubMed ID: 21371587
    [Abstract] [Full Text] [Related]

  • 10.
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  • 11. Protein structure determination by x-ray crystallography.
    Ilari A, Savino C.
    Methods Mol Biol; 2008 Jun 28; 452():63-87. PubMed ID: 18563369
    [Abstract] [Full Text] [Related]

  • 12. Computational tools in protein crystallography.
    Jain D, Lamour V.
    Methods Mol Biol; 2010 Jun 28; 673():129-56. PubMed ID: 20835796
    [Abstract] [Full Text] [Related]

  • 13. The use of molecular graphics in structure-based drug design.
    Emsley P, Debreczeni JE.
    Methods Mol Biol; 2012 Jun 28; 841():143-59. PubMed ID: 22222451
    [Abstract] [Full Text] [Related]

  • 14. In-plate protein crystallization, in situ ligand soaking and X-ray diffraction.
    le Maire A, Gelin M, Pochet S, Hoh F, Pirocchi M, Guichou JF, Ferrer JL, Labesse G.
    Acta Crystallogr D Biol Crystallogr; 2011 Sep 28; 67(Pt 9):747-55. PubMed ID: 21904027
    [Abstract] [Full Text] [Related]

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  • 16. Crystallographic fragment screening.
    Badger J.
    Methods Mol Biol; 2012 Sep 28; 841():161-77. PubMed ID: 22222452
    [Abstract] [Full Text] [Related]

  • 17.
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  • 18. Locating and characterizing binding sites on proteins.
    Mattos C, Ringe D.
    Nat Biotechnol; 1996 May 28; 14(5):595-9. PubMed ID: 9630949
    [Abstract] [Full Text] [Related]

  • 19.
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  • 20. PRODRG: a tool for high-throughput crystallography of protein-ligand complexes.
    Schüttelkopf AW, van Aalten DM.
    Acta Crystallogr D Biol Crystallogr; 2004 Aug 28; 60(Pt 8):1355-63. PubMed ID: 15272157
    [Abstract] [Full Text] [Related]


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