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Journal Abstract Search

300 related items for PubMed ID: 2069595

  • 1.
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  • 3. Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms.
    Commandeur JN, Brakenhoff JP, De Kanter FJ, Vermeulen NP.
    Biochem Pharmacol; 1988 Dec 01; 37(23):4495-504. PubMed ID: 3202890
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  • 4. Bioactivation of the cysteine-S-conjugate and mercapturic acid of tetrafluoroethylene to acylating reactive intermediates in the rat: dependence of activation and deactivation activities on acetyl coenzyme A availability.
    Commandeur JN, De Kanter FJ, Vermeulen NP.
    Mol Pharmacol; 1989 Oct 01; 36(4):654-63. PubMed ID: 2811861
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  • 5. Nephrotoxicity and hepatotoxicity of 1,1-dichloro-2,2-difluoroethylene in the rat. Indications for differential mechanisms of bioactivation.
    Commandeur JN, Oostendorp RA, Schoofs PR, Xu B, Vermeulen NP.
    Biochem Pharmacol; 1987 Dec 15; 36(24):4229-37. PubMed ID: 3689448
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  • 6. Bioactivation of S-(2,2-dihalo-1,1-difluoroethyl)-L-cysteines and S-(trihalovinyl)-L-cysteines by cysteine S-conjugate beta-lyase: indications for formation of both thionoacylating species and thiiranes as reactive intermediates.
    Commandeur JN, King LJ, Koymans L, Vermeulen NP.
    Chem Res Toxicol; 1996 Dec 15; 9(7):1092-102. PubMed ID: 8902263
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  • 7. Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl(1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat.
    Commandeur JN, Vermeulen NP.
    Chem Res Toxicol; 1990 Dec 15; 3(3):212-8. PubMed ID: 1966701
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  • 9. Biotransformation, excretion and nephrotoxicity of haloalkene-derived cysteine S-conjugates.
    Birner G, Bernauer U, Werner M, Dekant W.
    Arch Toxicol; 1997 Dec 15; 72(1):1-8. PubMed ID: 9458184
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  • 10. Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.
    Bernauer U, Birner G, Dekant W, Henschler D.
    Arch Toxicol; 1996 Dec 15; 70(6):338-46. PubMed ID: 8975632
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  • 11. Role of cytochrome P4503A in cysteine S-conjugates sulfoxidation and the nephrotoxicity of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in rats.
    Sheffels P, Schroeder JL, Altuntas TG, Liggitt HD, Kharasch ED.
    Chem Res Toxicol; 2004 Sep 15; 17(9):1177-89. PubMed ID: 15377151
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  • 12. Biotransformation of L-cysteine S-conjugates and N-acetyl-L-cysteine S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in human kidney in vitro: interindividual variability in N-acetylation, N-deacetylation, and beta-lyase-catalyzed metabolism.
    Gul Altuntas T, Kharasch ED.
    Drug Metab Dispos; 2002 Feb 15; 30(2):148-54. PubMed ID: 11792683
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  • 13. Efficient hepatic uptake and concentrative biliary excretion of a mercapturic acid.
    Hinchman CA, Rebbeor JF, Ballatori N.
    Am J Physiol; 1998 Oct 15; 275(4):G612-9. PubMed ID: 9756488
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  • 14. Deacetylation and further metabolism of the mercapturic acid of hexachloro-1,3-butadiene by rat kidney cytosol in vitro.
    Pratt IS, Lock EA.
    Arch Toxicol; 1988 Oct 15; 62(5):341-5. PubMed ID: 3242443
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  • 17. Dose-dependent metabolism of fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A), an anesthetic degradation product, to mercapturic acids and 3,3,3-trifluoro-2-(fluoromethoxy)propanoic acid in rats.
    Kharasch ED, Jubert C, Spracklin DK, Hoffman GM.
    Toxicol Appl Pharmacol; 1999 Oct 01; 160(1):49-59. PubMed ID: 10502502
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  • 19. The formation and biotransformation of cysteine conjugates of halogenated ethylenes by rabbit renal tubules.
    Hassall CD, Gandolfi AJ, Duhamel RC, Brendel K.
    Chem Biol Interact; 1984 May 01; 49(3):283-97. PubMed ID: 6547077
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  • 20. Specificity of aminoacylase III-mediated deacetylation of mercapturic acids.
    Newman D, Abuladze N, Scholz K, Dekant W, Tsuprun V, Ryazantsev S, Bondar G, Sassani P, Kurtz I, Pushkin A.
    Drug Metab Dispos; 2007 Jan 01; 35(1):43-50. PubMed ID: 17012540
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