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Journal Abstract Search

117 related items for PubMed ID: 20697602

  • 1. The role of GABA(A) receptor subtypes as analgesic targets.
    Mirza NR, Munro G.
    Drug News Perspect; 2010; 23(6):351-60. PubMed ID: 20697602
    [Abstract] [Full Text] [Related]

  • 2. Comparison of the novel subtype-selective GABAA receptor-positive allosteric modulator NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil, and gaboxadol in rat models of inflammatory and neuropathic pain.
    Munro G, Lopez-Garcia JA, Rivera-Arconada I, Erichsen HK, Nielsen EØ, Larsen JS, Ahring PK, Mirza NR.
    J Pharmacol Exp Ther; 2008 Dec; 327(3):969-81. PubMed ID: 18791060
    [Abstract] [Full Text] [Related]

  • 3. Developing analgesics by enhancing spinal inhibition after injury: GABAA receptor subtypes as novel targets.
    Munro G, Ahring PK, Mirza NR.
    Trends Pharmacol Sci; 2009 Sep; 30(9):453-9. PubMed ID: 19729210
    [Abstract] [Full Text] [Related]

  • 4. A question of balance--positive versus negative allosteric modulation of GABA(A) receptor subtypes as a driver of analgesic efficacy in rat models of inflammatory and neuropathic pain.
    Munro G, Erichsen HK, Rae MG, Mirza NR.
    Neuropharmacology; 2011 Sep; 61(1-2):121-32. PubMed ID: 21439986
    [Abstract] [Full Text] [Related]

  • 5. GABAergic analgesia: new insights from mutant mice and subtype-selective agonists.
    Zeilhofer HU, Möhler H, Di Lio A.
    Trends Pharmacol Sci; 2009 Aug; 30(8):397-402. PubMed ID: 19616317
    [Abstract] [Full Text] [Related]

  • 6. NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile], a unique subtype-selective GABAA receptor positive allosteric modulator: in vitro actions, pharmacokinetic properties and in vivo anxiolytic efficacy.
    Mirza NR, Larsen JS, Mathiasen C, Jacobsen TA, Munro G, Erichsen HK, Nielsen AN, Troelsen KB, Nielsen EØ, Ahring PK.
    J Pharmacol Exp Ther; 2008 Dec; 327(3):954-68. PubMed ID: 18791063
    [Abstract] [Full Text] [Related]

  • 7. Reversal of pathological pain through specific spinal GABAA receptor subtypes.
    Knabl J, Witschi R, Hösl K, Reinold H, Zeilhofer UB, Ahmadi S, Brockhaus J, Sergejeva M, Hess A, Brune K, Fritschy JM, Rudolph U, Möhler H, Zeilhofer HU.
    Nature; 2008 Jan 17; 451(7176):330-4. PubMed ID: 18202657
    [Abstract] [Full Text] [Related]

  • 8. The value of genetic and pharmacological approaches to understanding the complexities of GABA(A) receptor subtype functions: the anxiolytic effects of benzodiazepines.
    Reynolds DS.
    Pharmacol Biochem Behav; 2008 Jul 17; 90(1):37-42. PubMed ID: 18457867
    [Abstract] [Full Text] [Related]

  • 9. Restoring the spinal pain gate: GABA(A) receptors as targets for novel analgesics.
    Zeilhofer HU, Ralvenius WT, Acuña MA.
    Adv Pharmacol; 2015 Jul 17; 73():71-96. PubMed ID: 25637438
    [Abstract] [Full Text] [Related]

  • 10. Centrally-mediated antinociceptive actions of GABA(A) receptor agonists in the rat spared nerve injury model of neuropathic pain.
    Rode F, Jensen DG, Blackburn-Munro G, Bjerrum OJ.
    Eur J Pharmacol; 2005 Jun 01; 516(2):131-8. PubMed ID: 15936014
    [Abstract] [Full Text] [Related]

  • 11. Novel GABA(B) receptor positive modulators: a patent survey.
    Froestl W.
    Expert Opin Ther Pat; 2010 Aug 01; 20(8):1007-17. PubMed ID: 20645682
    [Abstract] [Full Text] [Related]

  • 12. Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats.
    Hansen RR, Erichsen HK, Brown DT, Mirza NR, Munro G.
    Neuropharmacology; 2012 Dec 01; 63(8):1360-7. PubMed ID: 22985969
    [Abstract] [Full Text] [Related]

  • 13. Endocannabinoids and pain: spinal and peripheral analgesia in inflammation and neuropathy.
    Rice AS, Farquhar-Smith WP, Nagy I.
    Prostaglandins Leukot Essent Fatty Acids; 2002 Dec 01; 66(2-3):243-56. PubMed ID: 12052040
    [Abstract] [Full Text] [Related]

  • 14. [GABA(A) benzodiazepine receptors and epilepsy].
    Sieghart W.
    Wien Klin Wochenschr; 1990 Mar 30; 102(7):197-201. PubMed ID: 2160756
    [Abstract] [Full Text] [Related]

  • 15. Pharmacology of the human gamma-aminobutyric acidA receptor alpha 4 subunit expressed in Xenopus laevis oocytes.
    Whittemore ER, Yang W, Drewe JA, Woodward RM.
    Mol Pharmacol; 1996 Nov 30; 50(5):1364-75. PubMed ID: 8913369
    [Abstract] [Full Text] [Related]

  • 16. GABA(A) receptor subtypes as targets for neuropsychiatric drug development.
    Korpi ER, Sinkkonen ST.
    Pharmacol Ther; 2006 Jan 30; 109(1-2):12-32. PubMed ID: 15996746
    [Abstract] [Full Text] [Related]

  • 17. Alteration in the sensitivity of GABA(A) receptors to allosteric modulatory drugs in rat hippocampus after chronic intermittent ethanol treatment.
    Kang MH, Spigelman I, Olsen RW.
    Alcohol Clin Exp Res; 1998 Dec 30; 22(9):2165-73. PubMed ID: 9884165
    [Abstract] [Full Text] [Related]

  • 18. GABA(A) receptor modulation: potential to deliver novel pain medicines?
    Munro G, Hansen RR, Mirza NR.
    Eur J Pharmacol; 2013 Sep 15; 716(1-3):17-23. PubMed ID: 23500203
    [Abstract] [Full Text] [Related]

  • 19. Pharmacological and computational analysis of alpha-subunit preferential GABA(A) positive allosteric modulators on the rat septo-hippocampal activity.
    Ujfalussy B, Kiss T, Orbán G, Hoffmann WE, Erdi P, Hajós M.
    Neuropharmacology; 2007 Mar 15; 52(3):733-43. PubMed ID: 17113111
    [Abstract] [Full Text] [Related]

  • 20. Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon.
    Hodge CW, Mehmert KK, Kelley SP, McMahon T, Haywood A, Olive MF, Wang D, Sanchez-Perez AM, Messing RO.
    Nat Neurosci; 1999 Nov 15; 2(11):997-1002. PubMed ID: 10526339
    [Abstract] [Full Text] [Related]

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