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Journal Abstract Search

599 related items for PubMed ID: 20718414

  • 1. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
    Sparapani S, Haider SM, Doria F, Gunaratnam M, Neidle S.
    J Am Chem Soc; 2010 Sep 08; 132(35):12263-72. PubMed ID: 20718414
    [Abstract] [Full Text] [Related]

  • 2. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
    Moore MJ, Schultes CM, Cuesta J, Cuenca F, Gunaratnam M, Tanious FA, Wilson WD, Neidle S.
    J Med Chem; 2006 Jan 26; 49(2):582-99. PubMed ID: 16420044
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands.
    Laronze-Cochard M, Kim YM, Brassart B, Riou JF, Laronze JY, Sapi J.
    Eur J Med Chem; 2009 Oct 26; 44(10):3880-8. PubMed ID: 19467742
    [Abstract] [Full Text] [Related]

  • 4. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
    Collie GW, Promontorio R, Hampel SM, Micco M, Neidle S, Parkinson GN.
    J Am Chem Soc; 2012 Feb 08; 134(5):2723-31. PubMed ID: 22280460
    [Abstract] [Full Text] [Related]

  • 5. Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures.
    Garner TP, Williams HE, Gluszyk KI, Roe S, Oldham NJ, Stevens MF, Moses JE, Searle MS.
    Org Biomol Chem; 2009 Oct 21; 7(20):4194-200. PubMed ID: 19795057
    [Abstract] [Full Text] [Related]

  • 6. Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents.
    Martins C, Gunaratnam M, Stuart J, Makwana V, Greciano O, Reszka AP, Kelland LR, Neidle S.
    Bioorg Med Chem Lett; 2007 Apr 15; 17(8):2293-8. PubMed ID: 17276687
    [Abstract] [Full Text] [Related]

  • 7. DNA loop sequence as the determinant for chiral supramolecular compound G-quadruplex selectivity.
    Yu H, Zhao C, Chen Y, Fu M, Ren J, Qu X.
    J Med Chem; 2010 Jan 14; 53(1):492-8. PubMed ID: 19911822
    [Abstract] [Full Text] [Related]

  • 8. Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors.
    Read M, Harrison RJ, Romagnoli B, Tanious FA, Gowan SH, Reszka AP, Wilson WD, Kelland LR, Neidle S.
    Proc Natl Acad Sci U S A; 2001 Apr 24; 98(9):4844-9. PubMed ID: 11309493
    [Abstract] [Full Text] [Related]

  • 9. Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands.
    Moorhouse AD, Haider S, Gunaratnam M, Munnur D, Neidle S, Moses JE.
    Mol Biosyst; 2008 Jun 24; 4(6):629-42. PubMed ID: 18493662
    [Abstract] [Full Text] [Related]

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  • 12. 12-N-Methylated 5,6-dihydrobenzo[c]acridine derivatives: a new class of highly selective ligands for c-myc G-quadruplex DNA.
    Liao SR, Zhou CX, Wu WB, Ou TM, Tan JH, Li D, Gu LQ, Huang ZS.
    Eur J Med Chem; 2012 Jul 24; 53():52-63. PubMed ID: 22513122
    [Abstract] [Full Text] [Related]

  • 13. Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
    Tan JH, Ou TM, Hou JQ, Lu YJ, Huang SL, Luo HB, Wu JY, Huang ZS, Wong KY, Gu LQ.
    J Med Chem; 2009 May 14; 52(9):2825-35. PubMed ID: 19354252
    [Abstract] [Full Text] [Related]

  • 14. Click chemistry assembly of G-quadruplex ligands incorporating a diarylurea scaffold and triazole linkers.
    Drewe WC, Neidle S.
    Chem Commun (Camb); 2008 Nov 14; (42):5295-7. PubMed ID: 18985188
    [Abstract] [Full Text] [Related]

  • 15. Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents.
    Cheng MK, Modi C, Cookson JC, Hutchinson I, Heald RA, McCarroll AJ, Missailidis S, Tanious F, Wilson WD, Mergny JL, Laughton CA, Stevens MF.
    J Med Chem; 2008 Feb 28; 51(4):963-75. PubMed ID: 18247546
    [Abstract] [Full Text] [Related]

  • 16. Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Wu WB, Chen SH, Hou JQ, Tan JH, Ou TM, Huang SL, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2011 Apr 21; 9(8):2975-86. PubMed ID: 21373680
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  • 18. Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.
    Campbell NH, Karim NH, Parkinson GN, Gunaratnam M, Petrucci V, Todd AK, Vilar R, Neidle S.
    J Med Chem; 2012 Jan 12; 55(1):209-22. PubMed ID: 22112241
    [Abstract] [Full Text] [Related]

  • 19. Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
    Bhattacharya S, Chaudhuri P, Jain AK, Paul A.
    Bioconjug Chem; 2010 Jul 21; 21(7):1148-59. PubMed ID: 20536245
    [Abstract] [Full Text] [Related]

  • 20. C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: anticancer profile and G-quadruplex stabilization.
    Lavrado J, Reszka AP, Moreira R, Neidle S, Paulo A.
    Bioorg Med Chem Lett; 2010 Dec 01; 20(23):7042-5. PubMed ID: 20952194
    [Abstract] [Full Text] [Related]

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