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Journal Abstract Search

214 related items for PubMed ID: 20724802

  • 1. Inhibition of P-glycoprotein-mediated efflux of digoxin and its metabolites by macrolide antibiotics.
    Hughes J, Crowe A.
    J Pharmacol Sci; 2010; 113(4):315-24. PubMed ID: 20724802
    [Abstract] [Full Text] [Related]

  • 2. Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies.
    Eberl S, Renner B, Neubert A, Reisig M, Bachmakov I, König J, Dörje F, Mürdter TE, Ackermann A, Dormann H, Gassmann KG, Hahn EG, Zierhut S, Brune K, Fromm MF.
    Clin Pharmacokinet; 2007; 46(12):1039-49. PubMed ID: 18027988
    [Abstract] [Full Text] [Related]

  • 3. Black ginger extract and its active compound, 5,7-dimethoxyflavone, increase intestinal drug absorption via efflux drug transporter inhibitions.
    Boonnop R, Meetam P, Siangjong L, Tuchinda P, Thongphasuk P, Soodvilai S, Soodvilai S.
    Drug Metab Pharmacokinet; 2023 Jun; 50():100500. PubMed ID: 36948091
    [Abstract] [Full Text] [Related]

  • 4. Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.
    Elsby R, Surry DD, Smith VN, Gray AJ.
    Xenobiotica; 2008 Jul; 38(7-8):1140-64. PubMed ID: 18668443
    [Abstract] [Full Text] [Related]

  • 5. Phorbol 12-myristate 13-acetate inhibits P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell monolayer models.
    Li YH, Bi HC, Huang L, Jin J, Zhong GP, Zhou XN, Huang M.
    Acta Pharmacol Sin; 2014 Feb; 35(2):283-91. PubMed ID: 24362330
    [Abstract] [Full Text] [Related]

  • 6. Cotransport of macrolide and fluoroquinolones, a beneficial interaction reversing P-glycoprotein efflux.
    Sikri V, Pal D, Jain R, Kalyani D, Mitra AK.
    Am J Ther; 2004 Feb; 11(6):433-42. PubMed ID: 15543082
    [Abstract] [Full Text] [Related]

  • 7. Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers.
    Troutman MD, Thakker DR.
    Pharm Res; 2003 Aug; 20(8):1200-9. PubMed ID: 12948018
    [Abstract] [Full Text] [Related]

  • 8. Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model.
    Pachot JI, Botham RP, Haegele KD, Hwang K.
    J Pharm Pharm Sci; 2003 Aug; 6(1):1-12. PubMed ID: 12753725
    [Abstract] [Full Text] [Related]

  • 9. Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats.
    Zhang H, Yao M, Morrison RA, Chong S.
    Arch Pharm Res; 2003 Sep; 26(9):768-72. PubMed ID: 14560928
    [Abstract] [Full Text] [Related]

  • 10. Characterization of efflux transporters involved in distribution and disposition of apixaban.
    Zhang D, He K, Herbst JJ, Kolb J, Shou W, Wang L, Balimane PV, Han YH, Gan J, Frost CE, Humphreys WG.
    Drug Metab Dispos; 2013 Apr; 41(4):827-35. PubMed ID: 23382458
    [Abstract] [Full Text] [Related]

  • 11. Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells.
    Zhang S, Morris ME.
    Pharm Res; 2003 Aug; 20(8):1184-91. PubMed ID: 12948016
    [Abstract] [Full Text] [Related]

  • 12. Effect of macrolide antibiotics on uptake of digoxin into rat liver.
    Ito S, Nasu R, Tsujimoto M, Murakami H, Ohtani H, Sawada Y.
    Biopharm Drug Dispos; 2007 Apr; 28(3):113-23. PubMed ID: 17253595
    [Abstract] [Full Text] [Related]

  • 13. Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors.
    Profit L, Eagling VA, Back DJ.
    AIDS; 1999 Sep 10; 13(13):1623-7. PubMed ID: 10509562
    [Abstract] [Full Text] [Related]

  • 14. Loxapine P-glycoprotein interactions in vitro.
    Reed A, Huie K, Perloff ES, Cassella JV, Takahashi LH.
    Drug Metab Lett; 2012 Mar 10; 6(1):26-32. PubMed ID: 22300294
    [Abstract] [Full Text] [Related]

  • 15. pH dependent uptake of loperamide across the gastrointestinal tract: an in vitro study.
    Crowe A, Wong P.
    Drug Dev Ind Pharm; 2004 May 10; 30(5):449-59. PubMed ID: 15244080
    [Abstract] [Full Text] [Related]

  • 16. Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data.
    Chaudhry A, Chung G, Lynn A, Yalvigi A, Brown C, Ellens H, O'Connor M, Lee C, Bentz J.
    Drug Metab Dispos; 2018 Mar 10; 46(3):279-290. PubMed ID: 29317410
    [Abstract] [Full Text] [Related]

  • 17. Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?
    Tang F, Horie K, Borchardt RT.
    Pharm Res; 2002 Jun 10; 19(6):765-72. PubMed ID: 12134945
    [Abstract] [Full Text] [Related]

  • 18. P-glycoprotein mediated efflux in Caco-2 cell monolayers: the influence of herbals on digoxin transport.
    Oga EF, Sekine S, Shitara Y, Horie T.
    J Ethnopharmacol; 2012 Dec 18; 144(3):612-7. PubMed ID: 23064285
    [Abstract] [Full Text] [Related]

  • 19. Application and limitation of inhibitors in drug-transporter interactions studies.
    Wang Q, Strab R, Kardos P, Ferguson C, Li J, Owen A, Hidalgo IJ.
    Int J Pharm; 2008 May 22; 356(1-2):12-8. PubMed ID: 18272304
    [Abstract] [Full Text] [Related]

  • 20. Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
    Raeissi SD, Hidalgo IJ, Segura-Aguilar J, Artursson P.
    Pharm Res; 1999 May 22; 16(5):625-32. PubMed ID: 10350002
    [Abstract] [Full Text] [Related]

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