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Journal Abstract Search

192 related items for PubMed ID: 20726001

  • 1. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer.
    Abdull Razis AF, Iori R, Ioannides C.
    Int J Cancer; 2011 Jun 15; 128(12):2775-82. PubMed ID: 20726001
    [Abstract] [Full Text] [Related]

  • 2. Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality.
    Abdull Razis AF, Bagatta M, De Nicola GR, Iori R, Ioannides C.
    Arch Toxicol; 2011 Aug 15; 85(8):919-27. PubMed ID: 21132492
    [Abstract] [Full Text] [Related]

  • 3. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes.
    Gerhäuser C, You M, Liu J, Moriarty RM, Hawthorne M, Mehta RG, Moon RC, Pezzuto JM.
    Cancer Res; 1997 Jan 15; 57(2):272-8. PubMed ID: 9000567
    [Abstract] [Full Text] [Related]

  • 4. Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane.
    Hanlon N, Coldham N, Sauer MJ, Ioannides C.
    Chem Biol Interact; 2009 Jan 27; 177(2):115-20. PubMed ID: 18823965
    [Abstract] [Full Text] [Related]

  • 5. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
    Zhang Y, Talalay P, Cho CG, Posner GH.
    Proc Natl Acad Sci U S A; 1992 Mar 15; 89(6):2399-403. PubMed ID: 1549603
    [Abstract] [Full Text] [Related]

  • 6. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity.
    Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C.
    Int J Cancer; 2005 Nov 10; 117(3):356-62. PubMed ID: 15906351
    [Abstract] [Full Text] [Related]

  • 7. Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin.
    Abdull Razis AF, Bagatta M, De Nicola GR, Iori R, Ioannides C.
    Lung Cancer; 2011 Mar 10; 71(3):298-305. PubMed ID: 20638746
    [Abstract] [Full Text] [Related]

  • 8. Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an isothiocyanate structurally related to sulforaphane.
    Hanlon N, Okpara A, Coldham N, Sauer MJ, Ioannides C.
    J Agric Food Chem; 2008 Sep 10; 56(17):7866-71. PubMed ID: 18680373
    [Abstract] [Full Text] [Related]

  • 9. A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.
    Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.
    Eur J Nutr; 2013 Apr 10; 52(3):1279-85. PubMed ID: 22710810
    [Abstract] [Full Text] [Related]

  • 10. Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane.
    Hanlon N, Coldham N, Sauer MJ, Ioannides C.
    Toxicology; 2008 Oct 30; 252(1-3):92-8. PubMed ID: 18773935
    [Abstract] [Full Text] [Related]

  • 11. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.
    Abdull Razis AF, Hanlon N, Soltys E, Krizova V, Iori R, Plant KE, Plant N, Ioannides C.
    Arch Toxicol; 2012 Oct 30; 86(10):1505-14. PubMed ID: 22643862
    [Abstract] [Full Text] [Related]

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  • 13. Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes.
    Posner GH, Cho CG, Green JV, Zhang Y, Talalay P.
    J Med Chem; 1994 Jan 07; 37(1):170-6. PubMed ID: 8289191
    [Abstract] [Full Text] [Related]

  • 14. Sulforaphane-mediated induction of a phase 2 detoxifying enzyme NAD(P)H:quinone reductase and apoptosis in human lymphoblastoid cells.
    Misiewicz I, Skupińska K, Kowalska E, Lubiński J, Kasprzycka-Guttman T.
    Acta Biochim Pol; 2004 Jan 07; 51(3):711-21. PubMed ID: 15448733
    [Abstract] [Full Text] [Related]

  • 15. The cruciferous nitrile crambene has bioactivity similar to sulforaphane when administered to Fischer 344 rats but is far less potent in cell culture.
    Keck AS, Staack R, Jeffery EH.
    Nutr Cancer; 2002 Jan 07; 42(2):233-40. PubMed ID: 12416265
    [Abstract] [Full Text] [Related]

  • 16. 4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent.
    Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.
    Arch Toxicol; 2012 Feb 07; 86(2):183-94. PubMed ID: 21960141
    [Abstract] [Full Text] [Related]

  • 17. Sulforaphane is superior to glucoraphanin in modulating carcinogen-metabolising enzymes in Hep G2 cells.
    Abdull Razis AF, Noor NM.
    Asian Pac J Cancer Prev; 2013 Feb 07; 14(7):4235-8. PubMed ID: 23991982
    [Abstract] [Full Text] [Related]

  • 18. Potent induction of phase 2 enzymes in human prostate cells by sulforaphane.
    Brooks JD, Paton VG, Vidanes G.
    Cancer Epidemiol Biomarkers Prev; 2001 Sep 07; 10(9):949-54. PubMed ID: 11535546
    [Abstract] [Full Text] [Related]

  • 19. Differential response of four human livers to modulation of phase II enzyme systems by the chemopreventive phytochemical phenethyl isothiocyanate.
    Konsue N, Ioannides C.
    Mol Nutr Food Res; 2010 Oct 07; 54(10):1477-85. PubMed ID: 20440691
    [Abstract] [Full Text] [Related]

  • 20. Cancer chemopreventive activity of sulforamate derivatives.
    Moriarty RM, Naithani R, Kosmeder J, Prakash O.
    Eur J Med Chem; 2006 Jan 07; 41(1):121-4. PubMed ID: 16300858
    [Abstract] [Full Text] [Related]

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