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212 related items for PubMed ID: 20736162

  • 1. Transamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretion.
    Zhou Y, Jetton TL, Goshorn S, Lynch CJ, She P.
    J Biol Chem; 2010 Oct 29; 285(44):33718-26. PubMed ID: 20736162
    [Abstract] [Full Text] [Related]

  • 2. Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice.
    Rabaglia ME, Gray-Keller MP, Frey BL, Shortreed MR, Smith LM, Attie AD.
    Am J Physiol Endocrinol Metab; 2005 Aug 29; 289(2):E218-24. PubMed ID: 15741243
    [Abstract] [Full Text] [Related]

  • 3. Distinguishing features of leucine and alpha-ketoisocaproate sensing in pancreatic beta-cells.
    Gao Z, Young RA, Li G, Najafi H, Buettger C, Sukumvanich SS, Wong RK, Wolf BA, Matschinsky FM.
    Endocrinology; 2003 May 29; 144(5):1949-57. PubMed ID: 12697702
    [Abstract] [Full Text] [Related]

  • 4. Identification of the mitochondrial branched chain aminotransferase as a branched chain alpha-keto acid transport protein.
    Hutson SM, Hall TR.
    J Biol Chem; 1993 Feb 15; 268(5):3084-91. PubMed ID: 8428987
    [Abstract] [Full Text] [Related]

  • 5. Alpha-ketoisocaproate is not a true substrate for ATP production by pancreatic beta-cell mitochondria.
    Lembert N, Idahl LA.
    Diabetes; 1998 Mar 15; 47(3):339-44. PubMed ID: 9519737
    [Abstract] [Full Text] [Related]

  • 6. The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic interaction of L-glutamine and 2-ketoisocaproate in pancreatic islets.
    Malaisse WJ, Sener A, Malaisse-Legae F, Hutton JC, Christophe J.
    Biochim Biophys Acta; 1981 Sep 18; 677(1):39-49. PubMed ID: 7028130
    [Abstract] [Full Text] [Related]

  • 7. Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria.
    Lenzen S, Schmidt W, Panten U.
    J Biol Chem; 1985 Oct 15; 260(23):12629-34. PubMed ID: 2864344
    [Abstract] [Full Text] [Related]

  • 8. 2-ketoglutarate generation in pancreatic B-cell mitochondria regulates insulin secretory action of amino acids and 2-keto acids.
    Lenzen S, Schmidt W, Rustenbeck I, Panten U.
    Biosci Rep; 1986 Feb 15; 6(2):163-9. PubMed ID: 3521757
    [Abstract] [Full Text] [Related]

  • 9. Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation.
    Panten U, Willenborg M, Schumacher K, Hamada A, Ghaly H, Rustenbeck I.
    Metabolism; 2013 Oct 15; 62(10):1375-86. PubMed ID: 23790612
    [Abstract] [Full Text] [Related]

  • 10. Use of sulfhydryl reagents to investigate branched chain alpha-keto acid transport in mitochondria.
    Drown PM, Torres N, Tovar AR, Davoodi J, Hutson SM.
    Biochim Biophys Acta; 2000 Sep 29; 1468(1-2):273-84. PubMed ID: 11018671
    [Abstract] [Full Text] [Related]

  • 11. Phosphate depletion impairs leucine-induced insulin secretion.
    Oh HY, Fadda GZ, Smogorzewski M, Liou HH, Massry SG.
    J Am Soc Nephrol; 1994 Nov 29; 5(5):1259-65. PubMed ID: 7873737
    [Abstract] [Full Text] [Related]

  • 12. Fuel-induced amplification of insulin secretion in mouse pancreatic islets exposed to a high sulfonylurea concentration: role of the NADPH/NADP+ ratio.
    Panten U, Rustenbeck I.
    Diabetologia; 2008 Jan 29; 51(1):101-9. PubMed ID: 17960358
    [Abstract] [Full Text] [Related]

  • 13. The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine.
    Malaisse WJ, Sener A, Malaisse-Lagae F, Welsh M, Matthews DE, Bier DM, Hellerström C.
    J Biol Chem; 1982 Aug 10; 257(15):8731-7. PubMed ID: 7047526
    [Abstract] [Full Text] [Related]

  • 14. Does leucine- and norleucine-induced insulin release depend on amino acid aminotransferase activity?
    Sener A, Malaisse-Lagae F, Malaisse WJ.
    J Biol Chem; 1983 Jun 10; 258(11):6693-4. PubMed ID: 6343380
    [Abstract] [Full Text] [Related]

  • 15. Respiration and insulin release in mouse pancreatic islets. Effects of L-leucine and 2-ketoisocaproate in combination with D-glucose and L-glutamine.
    Welsh M, Hellerström C, Andersson A.
    Biochim Biophys Acta; 1982 Oct 11; 721(2):178-84. PubMed ID: 6753947
    [Abstract] [Full Text] [Related]

  • 16. Decreased pancreatic islet response to L-leucine in the spontaneously diabetic GK rat: enzymatic, metabolic and secretory data.
    Giroix MH, Saulnier C, Portha B.
    Diabetologia; 1999 Aug 11; 42(8):965-77. PubMed ID: 10491757
    [Abstract] [Full Text] [Related]

  • 17. Preserved initiatory and potentiatory effect of alpha-ketoisocaproate on insulin release in islets of glucose intolerant rats.
    Guenifi A, Abdel-Halim SM, Efendic S, Ostenson CG.
    Diabetologia; 1998 Nov 11; 41(11):1368-73. PubMed ID: 9833946
    [Abstract] [Full Text] [Related]

  • 18. Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism.
    Hutson SM, Berkich D, Drown P, Xu B, Aschner M, LaNoue KF.
    J Neurochem; 1998 Aug 11; 71(2):863-74. PubMed ID: 9681479
    [Abstract] [Full Text] [Related]

  • 19. Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets.
    Hernández-Fisac I, Fernández-Pascual S, Ortsäter H, Pizarro-Delgado J, Martín del Río R, Bergsten P, Tamarit-Rodriguez J.
    Biochem J; 2006 Nov 15; 400(1):81-9. PubMed ID: 16819942
    [Abstract] [Full Text] [Related]

  • 20. Effect of alpha-ketoisocaproate and leucine on the in vivo oxidation of glutamate and glutamine in the rat brain.
    Zielke HR, Huang Y, Baab PJ, Collins RM, Zielke CL, Tildon JT.
    Neurochem Res; 1997 Sep 15; 22(9):1159-64. PubMed ID: 9251107
    [Abstract] [Full Text] [Related]

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