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209 related items for PubMed ID: 20737659

  • 1. Fructus ligustri lucidi extracts induce human glioma cell death through regulation of Akt/mTOR pathway in vitro and reduce glioma tumor growth in U87MG xenograft mouse model.
    Jeong JC, Kim JW, Kwon CH, Kim TH, Kim YK.
    Phytother Res; 2011 Mar; 25(3):429-34. PubMed ID: 20737659
    [Abstract] [Full Text] [Related]

  • 2. Mulberry fruit (Moris fructus) extracts induce human glioma cell death in vitro through ROS-dependent mitochondrial pathway and inhibits glioma tumor growth in vivo.
    Jeong JC, Jang SW, Kim TH, Kwon CH, Kim YK.
    Nutr Cancer; 2010 Mar; 62(3):402-12. PubMed ID: 20358478
    [Abstract] [Full Text] [Related]

  • 3. Lycii cortex radicis extract inhibits glioma tumor growth in vitro and in vivo through downregulation of the Akt/ERK pathway.
    Jeong JC, Kim SJ, Kim YK, Kwon CH, Kim KH.
    Oncol Rep; 2012 May; 27(5):1467-74. PubMed ID: 22266745
    [Abstract] [Full Text] [Related]

  • 4. Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin.
    Abe A, Kokuba H.
    Oncol Rep; 2013 Apr; 29(4):1333-42. PubMed ID: 23338618
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  • 5. Sorafenib induces apoptotic cell death in human non-small cell lung cancer cells by down-regulating mammalian target of rapamycin (mTOR)-dependent survivin expression.
    Kim YS, Jin HO, Seo SK, Woo SH, Choe TB, An S, Hong SI, Lee SJ, Lee KH, Park IC.
    Biochem Pharmacol; 2011 Aug 01; 82(3):216-26. PubMed ID: 21601561
    [Abstract] [Full Text] [Related]

  • 6. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
    Li CM, Narayanan R, Lu Y, Hurh E, Coss CC, Barrett CM, Miller DD, Dalton JT.
    Int J Oncol; 2010 Oct 01; 37(4):1023-30. PubMed ID: 20811725
    [Abstract] [Full Text] [Related]

  • 7. Effect of Fructus Ligustri Lucidi on osteoblastic like cell-line MC3T3-E1.
    Li Q, Fan YS, Gao ZQ, Fan K, Liu ZJ.
    J Ethnopharmacol; 2015 Jul 21; 170():88-95. PubMed ID: 25978950
    [Abstract] [Full Text] [Related]

  • 8. Curcumin dually inhibits both mammalian target of rapamycin and nuclear factor-κB pathways through a crossed phosphatidylinositol 3-kinase/Akt/IκB kinase complex signaling axis in adenoid cystic carcinoma.
    Sun ZJ, Chen G, Zhang W, Hu X, Liu Y, Zhou Q, Zhu LX, Zhao YF.
    Mol Pharmacol; 2011 Jan 21; 79(1):106-18. PubMed ID: 20959361
    [Abstract] [Full Text] [Related]

  • 9. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways.
    Aoki H, Takada Y, Kondo S, Sawaya R, Aggarwal BB, Kondo Y.
    Mol Pharmacol; 2007 Jul 21; 72(1):29-39. PubMed ID: 17395690
    [Abstract] [Full Text] [Related]

  • 10. Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis.
    Tang C, Lu YH, Xie JH, Wang F, Zou JN, Yang JS, Xing YY, Xi T.
    Anticancer Drugs; 2009 Apr 21; 20(4):249-58. PubMed ID: 19174695
    [Abstract] [Full Text] [Related]

  • 11. Aqueous extracts of Fructus Ligustri Lucidi enhance the sensitivity of human colorectal carcinoma DLD-1 cells to doxorubicin-induced apoptosis via Tbx3 suppression.
    Zhang JF, He ML, Qi Dong, Xie WD, Chen YC, Lin MC, Leung PC, Zhang YO, Kung HF.
    Integr Cancer Ther; 2011 Mar 21; 10(1):85-91. PubMed ID: 20702496
    [Abstract] [Full Text] [Related]

  • 12. Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma.
    Peponi E, Drakos E, Reyes G, Leventaki V, Rassidakis GZ, Medeiros LJ.
    Am J Pathol; 2006 Dec 21; 169(6):2171-80. PubMed ID: 17148679
    [Abstract] [Full Text] [Related]

  • 13. Anticancer activity of litchi fruit pericarp extract against human breast cancer in vitro and in vivo.
    Wang X, Yuan S, Wang J, Lin P, Liu G, Lu Y, Zhang J, Wang W, Wei Y.
    Toxicol Appl Pharmacol; 2006 Sep 01; 215(2):168-78. PubMed ID: 16563451
    [Abstract] [Full Text] [Related]

  • 14. Akt inhibitor shows anticancer and radiosensitizing effects in malignant glioma cells by inducing autophagy.
    Fujiwara K, Iwado E, Mills GB, Sawaya R, Kondo S, Kondo Y.
    Int J Oncol; 2007 Oct 01; 31(4):753-60. PubMed ID: 17786305
    [Abstract] [Full Text] [Related]

  • 15. Liqustri lucidi Fructus inhibits hepatic injury and functions as an antioxidant by activation of AMP-activated protein kinase in vivo and in vitro.
    Seo HL, Baek SY, Lee EH, Lee JH, Lee SG, Kim KY, Jang MH, Park MH, Kim JH, Kim KJ, Lee HS, Ahn SC, Lee JR, Park SJ, Kim SC, Kim YW.
    Chem Biol Interact; 2017 Jan 25; 262():57-68. PubMed ID: 27916511
    [Abstract] [Full Text] [Related]

  • 16. Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
    McMillin DW, Ooi M, Delmore J, Negri J, Hayden P, Mitsiades N, Jakubikova J, Maira SM, Garcia-Echeverria C, Schlossman R, Munshi NC, Richardson PG, Anderson KC, Mitsiades CS.
    Cancer Res; 2009 Jul 15; 69(14):5835-42. PubMed ID: 19584292
    [Abstract] [Full Text] [Related]

  • 17. Mammalian target of rapamycin as a novel target in the treatment of hepatocellular carcinoma.
    Guo Y, Liang X, Lu M, Weng T, Liu Y, Ye X.
    Hepatogastroenterology; 2010 Jul 15; 57(101):913-8. PubMed ID: 21033251
    [Abstract] [Full Text] [Related]

  • 18. Cytotoxic and Antiproliferative Effects of β-Mangostin on Rat C6 Glioma Cells Depend on Oxidative Stress Induction via PI3K/AKT/mTOR Pathway Inhibition.
    Li K, Wu L, Chen Y, Li Y, Wang Q, Li M, Hao K, Zhang W, Jiang S, Wang Z.
    Drug Des Devel Ther; 2020 Jul 15; 14():5315-5324. PubMed ID: 33293793
    [Abstract] [Full Text] [Related]

  • 19. Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma.
    Clark CA, McEachern MD, Shah SH, Rong Y, Rong X, Smelley CL, Caldito GC, Abreo FW, Nathan CO.
    Cancer Prev Res (Phila); 2010 Dec 15; 3(12):1586-95. PubMed ID: 20851953
    [Abstract] [Full Text] [Related]

  • 20. The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.
    Shin SY, Lee KS, Choi YK, Lim HJ, Lee HG, Lim Y, Lee YH.
    Carcinogenesis; 2013 Sep 15; 34(9):2080-9. PubMed ID: 23689352
    [Abstract] [Full Text] [Related]

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