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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

113 related items for PubMed ID: 20801551

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  • 6. Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide.
    Uto Y, Ogata T, Harada J, Kiyotsuka Y, Ueno Y, Miyazawa Y, Kurata H, Deguchi T, Watanabe N, Takagi T, Wakimoto S, Okuyama R, Abe M, Kurikawa N, Kawamura S, Yamato M, Osumi J.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4151-8. PubMed ID: 19540759
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  • 8. Discovery of novel SCD1 inhibitors: 5-alkyl-4,5-dihydro-3H-spiro[1,5-benzoxazepine-2,4'-piperidine] analogs.
    Uto Y, Ueno Y, Kiyotsuka Y, Miyazawa Y, Kurata H, Ogata T, Takagi T, Wakimoto S, Ohsumi J.
    Eur J Med Chem; 2011 May 01; 46(5):1892-6. PubMed ID: 21356569
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  • 9. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438).
    Léger S, Black WC, Deschenes D, Dolman S, Falgueyret JP, Gagnon M, Guiral S, Huang Z, Guay J, Leblanc Y, Li CS, Massé F, Oballa R, Zhang L.
    Bioorg Med Chem Lett; 2010 Jan 15; 20(2):499-502. PubMed ID: 20004097
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  • 11. Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors.
    Koltun DO, Parkhill EQ, Vasilevich NI, Glushkov AI, Zilbershtein TM, Ivanov AV, Cole AG, Henderson I, Zautke NA, Brunn SA, Mollova N, Leung K, Chisholm JW, Zablocki J.
    Bioorg Med Chem Lett; 2009 Apr 01; 19(7):2048-52. PubMed ID: 19249203
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  • 13. Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: from systemic to liver-targeting inhibitors.
    Ramtohul YK, Powell D, Leclerc JP, Leger S, Oballa R, Black C, Isabel E, Li CS, Crane S, Robichaud J, Guay J, Guiral S, Zhang L, Huang Z.
    Bioorg Med Chem Lett; 2011 Oct 01; 21(19):5692-6. PubMed ID: 21871798
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  • 15. Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series.
    Lachance N, Guiral S, Huang Z, Leclerc JP, Li CS, Oballa RM, Ramtohul YK, Wang H, Wu J, Zhang L.
    Bioorg Med Chem Lett; 2012 Jan 01; 22(1):623-7. PubMed ID: 22101133
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  • 18. Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents.
    Imamura K, Tomita N, Kawakita Y, Ito Y, Ono K, Nii N, Miyazaki T, Yonemori K, Tawada M, Sumi H, Satoh Y, Yamamoto Y, Miyahisa I, Sasaki M, Satomi Y, Hirayama M, Nishigaki R, Maezaki H.
    Bioorg Med Chem; 2017 Jul 15; 25(14):3768-3779. PubMed ID: 28571972
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  • 19. Nicotinic acids: liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy.
    Powell DA, Black WC, Bleasby K, Chan CC, Deschenes D, Gagnon M, Gordon R, Guay J, Guiral S, Hafey MJ, Huang Z, Isabel E, Leblanc Y, Styhler A, Xu LJ, Zhang L, Oballa RM.
    Bioorg Med Chem Lett; 2011 Dec 15; 21(24):7281-6. PubMed ID: 22047692
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