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453 related items for PubMed ID: 20807279

  • 1. Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation.
    Alcalai R, Wakimoto H, Arad M, Planer D, Konno T, Wang L, Seidman JG, Seidman CE, Berul CI.
    J Cardiovasc Electrophysiol; 2011 Mar; 22(3):316-24. PubMed ID: 20807279
    [Abstract] [Full Text] [Related]

  • 2. RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT.
    Kryshtal DO, Blackwell DJ, Egly CL, Smith AN, Batiste SM, Johnston JN, Laver DR, Knollmann BC.
    Circ Res; 2021 Feb 05; 128(3):321-331. PubMed ID: 33297863
    [Abstract] [Full Text] [Related]

  • 3. Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia.
    Song L, Alcalai R, Arad M, Wolf CM, Toka O, Conner DA, Berul CI, Eldar M, Seidman CE, Seidman JG.
    J Clin Invest; 2007 Jul 05; 117(7):1814-23. PubMed ID: 17607358
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.
    Hwang HS, Hasdemir C, Laver D, Mehra D, Turhan K, Faggioni M, Yin H, Knollmann BC.
    Circ Arrhythm Electrophysiol; 2011 Apr 05; 4(2):128-35. PubMed ID: 21270101
    [Abstract] [Full Text] [Related]

  • 5. Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation.
    Sedej S, Heinzel FR, Walther S, Dybkova N, Wakula P, Groborz J, Gronau P, Maier LS, Vos MA, Lai FA, Napolitano C, Priori SG, Kockskämper J, Pieske B.
    Cardiovasc Res; 2010 Jul 01; 87(1):50-9. PubMed ID: 20080988
    [Abstract] [Full Text] [Related]

  • 6. Functional consequences of stably expressing a mutant calsequestrin (CASQ2D307H) in the CASQ2 null background.
    Kalyanasundaram A, Viatchenko-Karpinski S, Belevych AE, Lacombe VA, Hwang HS, Knollmann BC, Gyorke S, Periasamy M.
    Am J Physiol Heart Circ Physiol; 2012 Jan 01; 302(1):H253-61. PubMed ID: 21984545
    [Abstract] [Full Text] [Related]

  • 7. Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia.
    Liu B, Walton SD, Ho HT, Belevych AE, Tikunova SB, Bonilla I, Shettigar V, Knollmann BC, Priori SG, Volpe P, Radwański PB, Davis JP, Györke S.
    J Am Heart Assoc; 2018 May 02; 7(10):. PubMed ID: 29720499
    [Abstract] [Full Text] [Related]

  • 8. Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.
    Shan J, Xie W, Betzenhauser M, Reiken S, Chen BX, Wronska A, Marks AR.
    Circ Res; 2012 Aug 31; 111(6):708-17. PubMed ID: 22828895
    [Abstract] [Full Text] [Related]

  • 9. Accentuated vagal antagonism paradoxically increases ryanodine receptor calcium leak in long-term exercised Calsequestrin2 knockout mice.
    Ho HT, Thambidorai S, Knollmann BC, Billman GE, Györke S, Kalyanasundaram A.
    Heart Rhythm; 2018 Mar 31; 15(3):430-441. PubMed ID: 29030236
    [Abstract] [Full Text] [Related]

  • 10. Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death.
    Terentyev D, Nori A, Santoro M, Viatchenko-Karpinski S, Kubalova Z, Gyorke I, Terentyeva R, Vedamoorthyrao S, Blom NA, Valle G, Napolitano C, Williams SC, Volpe P, Priori SG, Gyorke S.
    Circ Res; 2006 May 12; 98(9):1151-8. PubMed ID: 16601229
    [Abstract] [Full Text] [Related]

  • 11. Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT.
    Liu B, Ho HT, Brunello L, Unudurthi SD, Lou Q, Belevych AE, Qian L, Kim DH, Cho C, Janssen PM, Hund TJ, Knollmann BC, Kranias EG, Györke S.
    Cardiovasc Res; 2015 Nov 01; 108(2):299-311. PubMed ID: 26410369
    [Abstract] [Full Text] [Related]

  • 12. Abnormal calcium signaling and sudden cardiac death associated with mutation of calsequestrin.
    Viatchenko-Karpinski S, Terentyev D, Györke I, Terentyeva R, Volpe P, Priori SG, Napolitano C, Nori A, Williams SC, Györke S.
    Circ Res; 2004 Mar 05; 94(4):471-7. PubMed ID: 14715535
    [Abstract] [Full Text] [Related]

  • 13. Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.
    Hilliard FA, Steele DS, Laver D, Yang Z, Le Marchand SJ, Chopra N, Piston DW, Huke S, Knollmann BC.
    J Mol Cell Cardiol; 2010 Feb 05; 48(2):293-301. PubMed ID: 19835880
    [Abstract] [Full Text] [Related]

  • 14. EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2.
    Klipp RC, Li N, Wang Q, Word TA, Sibrian-Vazquez M, Strongin RM, Wehrens XHT, Abramson JJ.
    Heart Rhythm; 2018 Apr 05; 15(4):578-586. PubMed ID: 29248564
    [Abstract] [Full Text] [Related]

  • 15. Mechanism underlying catecholaminergic polymorphic ventricular tachycardia and approaches to therapy.
    Watanabe H, Knollmann BC.
    J Electrocardiol; 2011 Apr 05; 44(6):650-5. PubMed ID: 21872879
    [Abstract] [Full Text] [Related]

  • 16. Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice.
    Chopra N, Kannankeril PJ, Yang T, Hlaing T, Holinstat I, Ettensohn K, Pfeifer K, Akin B, Jones LR, Franzini-Armstrong C, Knollmann BC.
    Circ Res; 2007 Sep 14; 101(6):617-26. PubMed ID: 17656677
    [Abstract] [Full Text] [Related]

  • 17. Patient-Specific Drug Screening Using a Human Induced Pluripotent Stem Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Type 2.
    Maizels L, Huber I, Arbel G, Tijsen AJ, Gepstein A, Khoury A, Gepstein L.
    Circ Arrhythm Electrophysiol; 2017 Jun 14; 10(6):. PubMed ID: 28630169
    [Abstract] [Full Text] [Related]

  • 18. The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice.
    Zhang J, Chen B, Zhong X, Mi T, Guo A, Zhou Q, Tan Z, Wu G, Chen AW, Fill M, Song LS, Chen SR.
    Biochem J; 2014 Jul 01; 461(1):99-106. PubMed ID: 24758151
    [Abstract] [Full Text] [Related]

  • 19. Modulation of SR Ca release by luminal Ca and calsequestrin in cardiac myocytes: effects of CASQ2 mutations linked to sudden cardiac death.
    Terentyev D, Kubalova Z, Valle G, Nori A, Vedamoorthyrao S, Terentyeva R, Viatchenko-Karpinski S, Bers DM, Williams SC, Volpe P, Gyorke S.
    Biophys J; 2008 Aug 01; 95(4):2037-48. PubMed ID: 18469084
    [Abstract] [Full Text] [Related]

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