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Journal Abstract Search

86 related items for PubMed ID: 20807314

  • 1. Dilysine retrieval signal-containing p24 proteins collaborate in inhibiting γ-cleavage of amyloid precursor protein.
    Hasegawa H, Liu L, Nishimura M.
    J Neurochem; 2010 Nov; 115(3):771-81. PubMed ID: 20807314
    [Abstract] [Full Text] [Related]

  • 2. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.
    Zhou S, Zhou H, Walian PJ, Jap BK.
    Proc Natl Acad Sci U S A; 2005 May 24; 102(21):7499-504. PubMed ID: 15890777
    [Abstract] [Full Text] [Related]

  • 3. Catalytic site-directed gamma-secretase complex inhibitors do not discriminate pharmacologically between Notch S3 and beta-APP cleavages.
    Lewis HD, Pérez Revuelta BI, Nadin A, Neduvelil JG, Harrison T, Pollack SJ, Shearman MS.
    Biochemistry; 2003 Jun 24; 42(24):7580-6. PubMed ID: 12809514
    [Abstract] [Full Text] [Related]

  • 4. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
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  • 6. Biogenesis and processing of the amyloid precursor protein in the early secretory pathway.
    Selivanova A, Winblad B, Dantuma NP, Farmery MR.
    Biochem Biophys Res Commun; 2007 Jun 15; 357(4):1034-9. PubMed ID: 17466275
    [Abstract] [Full Text] [Related]

  • 7. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
    Martone RL, Zhou H, Atchison K, Comery T, Xu JZ, Huang X, Gong X, Jin M, Kreft A, Harrison B, Mayer SC, Aschmies S, Gonzales C, Zaleska MM, Riddell DR, Wagner E, Lu P, Sun SC, Sonnenberg-Reines J, Oganesian A, Adkins K, Leach MW, Clarke DW, Huryn D, Abou-Gharbia M, Magolda R, Bard J, Frick G, Raje S, Forlow SB, Balliet C, Burczynski ME, Reinhart PH, Wan HI, Pangalos MN, Jacobsen JS.
    J Pharmacol Exp Ther; 2009 Nov 15; 331(2):598-608. PubMed ID: 19671883
    [Abstract] [Full Text] [Related]

  • 8. Amyloid precursor protein promotes endoplasmic reticulum stress-induced cell death via C/EBP homologous protein-mediated pathway.
    Takahashi K, Niidome T, Akaike A, Kihara T, Sugimoto H.
    J Neurochem; 2009 Jun 15; 109(5):1324-37. PubMed ID: 19476545
    [Abstract] [Full Text] [Related]

  • 9. Presenilins: how much more than γ-secretase?!
    Coen K, Annaert W.
    Biochem Soc Trans; 2010 Dec 15; 38(6):1474-8. PubMed ID: 21118110
    [Abstract] [Full Text] [Related]

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  • 11. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.
    J Neurosci Res; 2003 Nov 01; 74(3):386-92. PubMed ID: 14598315
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  • 13. Functional diversity among p24 subfamily members.
    Strating JR, Hafmans TG, Martens GJ.
    Biol Cell; 2009 Apr 01; 101(4):207-19. PubMed ID: 18699773
    [Abstract] [Full Text] [Related]

  • 14. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
    Brijbassi S, Amtul Z, Newbigging S, Westaway D, St George-Hyslop P, Rozmahel RF.
    Neurobiol Dis; 2007 Feb 01; 25(2):291-6. PubMed ID: 17071095
    [Abstract] [Full Text] [Related]

  • 15. COPI-mediated retrograde transport is required for efficient gamma-secretase cleavage of the amyloid precursor protein.
    Selivanova A, Winblad B, Farmery MR, Dantuma NP, Ankarcrona M.
    Biochem Biophys Res Commun; 2006 Nov 10; 350(1):220-6. PubMed ID: 16999935
    [Abstract] [Full Text] [Related]

  • 16. Mutations in the transmembrane domain of APP altering gamma-secretase specificity.
    Lichtenthaler SF, Ida N, Multhaup G, Masters CL, Beyreuther K.
    Biochemistry; 1997 Dec 09; 36(49):15396-403. PubMed ID: 9398269
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  • 17. gamma-Secretase can cleave amyloid precursor protein fragments independent of alpha- and beta-secretase pre-cutting.
    Kume H, Sekijima Y, Maruyama K, Kametani F.
    Int J Mol Med; 2003 Jul 09; 12(1):57-60. PubMed ID: 12792809
    [Abstract] [Full Text] [Related]

  • 18. Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.
    Shin RW, Saido TC, Maeda M, Kitamoto T.
    Neurosci Lett; 2005 Mar 07; 376(1):14-9. PubMed ID: 15694266
    [Abstract] [Full Text] [Related]

  • 19. In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
    Hoke DE, Tan JL, Ilaya NT, Culvenor JG, Smith SJ, White AR, Masters CL, Evin GM.
    FEBS J; 2005 Nov 07; 272(21):5544-57. PubMed ID: 16262694
    [Abstract] [Full Text] [Related]

  • 20. Rac1 changes the substrate specificity of gamma-secretase between amyloid precursor protein and Notch1.
    Boo JH, Sohn JH, Kim JE, Song H, Mook-Jung I.
    Biochem Biophys Res Commun; 2008 Aug 08; 372(4):913-7. PubMed ID: 18538664
    [Abstract] [Full Text] [Related]

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