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Journal Abstract Search

122 related items for PubMed ID: 20807840

  • 1.
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  • 3. Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide (MK-0364), in rodents.
    Fong TM, Guan XM, Marsh DJ, Shen CP, Stribling DS, Rosko KM, Lao J, Yu H, Feng Y, Xiao JC, Van der Ploeg LH, Goulet MT, Hagmann WK, Lin LS, Lanza TJ, Jewell JP, Liu P, Shah SK, Qi H, Tong X, Wang J, Xu SS, Francis B, Strack AM, MacIntyre DE, Shearman LP.
    J Pharmacol Exp Ther; 2007 Jun; 321(3):1013-22. PubMed ID: 17327489
    [Abstract] [Full Text] [Related]

  • 4. Appetite-modifying effects of bombesin receptor subtype-3 agonists.
    Majumdar ID, Weber HC.
    Handb Exp Pharmacol; 2012 Jun; (209):405-32. PubMed ID: 22249826
    [Abstract] [Full Text] [Related]

  • 5. Biology and pharmacology of bombesin receptor subtype-3.
    Majumdar ID, Weber HC.
    Curr Opin Endocrinol Diabetes Obes; 2012 Feb; 19(1):3-7. PubMed ID: 22157398
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  • 6. Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.
    Guan XM, Chen H, Dobbelaar PH, Dong Y, Fong TM, Gagen K, Gorski J, He S, Howard AD, Jian T, Jiang M, Kan Y, Kelly TM, Kosinski J, Lin LS, Liu J, Marsh DJ, Metzger JM, Miller R, Nargund RP, Palyha O, Shearman L, Shen Z, Stearns R, Strack AM, Stribling S, Tang YS, Wang SP, White A, Yu H, Reitman ML.
    Cell Metab; 2010 Feb 03; 11(2):101-12. PubMed ID: 20096642
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  • 7. Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
    Liu J, He S, Jian T, Dobbelaar PH, Sebhat IK, Lin LS, Goodman A, Guo C, Guzzo PR, Hadden M, Henderson AJ, Pattamana K, Ruenz M, Sargent BJ, Swenson B, Yet L, Tamvakopoulos C, Peng Q, Pan J, Kan Y, Palyha O, Kelly TM, Guan XM, Howard AD, Marsh DJ, Metzger JM, Reitman ML, Wyvratt MJ, Nargund RP.
    Bioorg Med Chem Lett; 2010 Apr 01; 20(7):2074-7. PubMed ID: 20219372
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  • 9. Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents.
    Shearman LP, Stribling DS, Camacho RE, Rosko KM, Wang J, Tong S, Feng Y, Marsh DJ, Yu H, Guan X, Spann SK, Macneil DJ, Fong TM, Metzger JM, Goulet MT, Hagmann WK, Plummer CW, Finke PE, Mills SG, Shah SK, Truong Q, Van der Ploeg LH, Macintyre DE, Strack AM.
    Eur J Pharmacol; 2008 Jan 28; 579(1-3):215-24. PubMed ID: 18021763
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  • 10. Synergistic interaction between neuropeptide Y1 and Y5 receptor pathways in regulation of energy homeostasis.
    Mashiko S, Moriya R, Ishihara A, Gomori A, Matsushita H, Egashira S, Iwaasa H, Takahashi T, Haga Y, Fukami T, Kanatani A.
    Eur J Pharmacol; 2009 Aug 01; 615(1-3):113-7. PubMed ID: 19482021
    [Abstract] [Full Text] [Related]

  • 11. A Selective Bombesin Receptor Subtype 3 Agonist Promotes Weight Loss in Male Diet-Induced-Obese Rats With Circadian Rhythm Change.
    Nio Y, Hotta N, Maruyama M, Hamagami K, Nagi T, Funata M, Sakamoto J, Nakakariya M, Amano N, Okawa T, Arikawa Y, Sasaki S, Okuda S, Kasai S, Habata Y, Nagisa Y.
    Endocrinology; 2017 May 01; 158(5):1298-1313. PubMed ID: 28324017
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  • 12. Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
    Hadden M, Goodman A, Guo C, Guzzo PR, Henderson AJ, Pattamana K, Ruenz M, Sargent BJ, Swenson B, Yet L, Liu J, He S, Sebhat IK, Lin LS, Tamvakopoulos C, Peng Q, Kan Y, Palyha O, Kelly TM, Guan XM, Metzger JM, Reitman ML, Nargund RP.
    Bioorg Med Chem Lett; 2010 May 01; 20(9):2912-5. PubMed ID: 20347296
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  • 13. Regulation of body temperature and brown adipose tissue thermogenesis by bombesin receptor subtype-3.
    Lateef DM, Abreu-Vieira G, Xiao C, Reitman ML.
    Am J Physiol Endocrinol Metab; 2014 Mar 01; 306(6):E681-7. PubMed ID: 24452453
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  • 14. Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity.
    Ohki-Hamazaki H, Watase K, Yamamoto K, Ogura H, Yamano M, Yamada K, Maeno H, Imaki J, Kikuyama S, Wada E, Wada K.
    Nature; 1997 Nov 13; 390(6656):165-9. PubMed ID: 9367152
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  • 15. Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice.
    Ito M, Ishihara A, Gomori A, Egashira S, Matsushita H, Mashiko S, Ito J, Ito M, Nakase K, Haga Y, Iwaasa H, Suzuki T, Ohtake N, Moriya M, Sato N, MacNeil DJ, Takenaga N, Tokita S, Kanatani A.
    Eur J Pharmacol; 2009 Dec 10; 624(1-3):77-83. PubMed ID: 19836369
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  • 16. Novel selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models.
    Chen W, Tang H, Liu H, Long L, Gong Z, Zheng J, Chi M, Xie Y, Zheng Z, Li S, Wang L.
    Eur J Pharmacol; 2010 Jul 10; 637(1-3):178-85. PubMed ID: 20380831
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  • 17. Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism.
    Xiao C, Piñol RA, Carlin JL, Li C, Deng C, Gavrilova O, Reitman ML.
    Mol Metab; 2017 Nov 10; 6(11):1540-1550. PubMed ID: 29107299
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  • 18. Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.
    Kowalski TJ, Spar BD, Weig B, Farley C, Cook J, Ghibaudi L, Fried S, O'Neill K, Del Vecchio RA, McBriar M, Guzik H, Clader J, Hawes BE, Hwa J.
    Eur J Pharmacol; 2006 Mar 27; 535(1-3):182-91. PubMed ID: 16540104
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  • 19. Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats.
    Roth JD, Trevaskis JL, Wilson J, Lei C, Athanacio J, Mack C, Kesty NC, Coffey T, Weyer C, Parkes DG.
    Int J Obes (Lond); 2008 Aug 27; 32(8):1201-10. PubMed ID: 18560368
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