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Journal Abstract Search

124 related items for PubMed ID: 20813094

  • 1. Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells.
    Kalle AM, Mallika A, Badiger J, Alinakhi, Talukdar P, Sachchidanand.
    Biochem Biophys Res Commun; 2010 Oct 08; 401(1):13-9. PubMed ID: 20813094
    [Abstract] [Full Text] [Related]

  • 2. [Mechanism of apoptosis induced by SIRT1 deacetylase inhibitors in human breast cancer MCF-7 drug-resistant cells].
    Li Y, Xu R, Zhang XM, Li DD, He QY.
    Yao Xue Xue Bao; 2008 Oct 08; 43(10):1003-10. PubMed ID: 19127863
    [Abstract] [Full Text] [Related]

  • 3. Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells.
    Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozaki K, Akishita M, Ouchi Y, Kaneki M.
    Oncogene; 2006 Jan 12; 25(2):176-85. PubMed ID: 16170353
    [Abstract] [Full Text] [Related]

  • 4. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 12; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 5. Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
    Lara E, Mai A, Calvanese V, Altucci L, Lopez-Nieva P, Martinez-Chantar ML, Varela-Rey M, Rotili D, Nebbioso A, Ropero S, Montoya G, Oyarzabal J, Velasco S, Serrano M, Witt M, Villar-Garea A, Imhof A, Mato JM, Esteller M, Fraga MF.
    Oncogene; 2009 Feb 12; 28(6):781-91. PubMed ID: 19060927
    [Abstract] [Full Text] [Related]

  • 6. Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells.
    Wang J, Kim TH, Ahn MY, Lee J, Jung JH, Choi WS, Lee BM, Yoon KS, Yoon S, Kim HS.
    Int J Oncol; 2012 Sep 12; 41(3):1101-9. PubMed ID: 22751989
    [Abstract] [Full Text] [Related]

  • 7. Potent in vivo anti-breast cancer activity of IN-2001, a novel inhibitor of histone deacetylase, in MMTV/c-Neu mice.
    Joung KE, Min KN, An JY, Kim DK, Kong G, Sheen YY.
    Cancer Res; 2006 May 15; 66(10):5394-402. PubMed ID: 16707467
    [Abstract] [Full Text] [Related]

  • 8. SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein.
    Kuo SJ, Lin HY, Chien SY, Chen DR.
    Oncol Rep; 2013 Jul 15; 30(1):125-30. PubMed ID: 23673452
    [Abstract] [Full Text] [Related]

  • 9. Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases.
    Mahboobi S, Dove S, Sellmer A, Winkler M, Eichhorn E, Pongratz H, Ciossek T, Baer T, Maier T, Beckers T.
    J Med Chem; 2009 Apr 23; 52(8):2265-79. PubMed ID: 19301902
    [Abstract] [Full Text] [Related]

  • 10. Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells.
    Chien SY, Wu YC, Chung JG, Yang JS, Lu HF, Tsou MF, Wood WG, Kuo SJ, Chen DR.
    Hum Exp Toxicol; 2009 Aug 23; 28(8):493-503. PubMed ID: 19755441
    [Abstract] [Full Text] [Related]

  • 11. A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells.
    Kojima K, Ohhashi R, Fujita Y, Hamada N, Akao Y, Nozawa Y, Deguchi T, Ito M.
    Biochem Biophys Res Commun; 2008 Aug 29; 373(3):423-8. PubMed ID: 18573234
    [Abstract] [Full Text] [Related]

  • 12. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
    Massey AJ, Williamson DS, Browne H, Murray JB, Dokurno P, Shaw T, Macias AT, Daniels Z, Geoffroy S, Dopson M, Lavan P, Matassova N, Francis GL, Graham CJ, Parsons R, Wang Y, Padfield A, Comer M, Drysdale MJ, Wood M.
    Cancer Chemother Pharmacol; 2010 Aug 29; 66(3):535-45. PubMed ID: 20012863
    [Abstract] [Full Text] [Related]

  • 13. New aryldithiolethione derivatives as potent histone deacetylase inhibitors.
    Tazzari V, Cappelletti G, Casagrande M, Perrino E, Renzi L, Del Soldato P, Sparatore A.
    Bioorg Med Chem; 2010 Jun 15; 18(12):4187-94. PubMed ID: 20576572
    [Abstract] [Full Text] [Related]

  • 14. Downregulation of Sirt1 by antisense oligonucleotides induces apoptosis and enhances radiation sensitization in A549 lung cancer cells.
    Sun Y, Sun D, Li F, Tian L, Li C, Li L, Lin R, Wang S.
    Lung Cancer; 2007 Oct 15; 58(1):21-9. PubMed ID: 17624472
    [Abstract] [Full Text] [Related]

  • 15. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 16. Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes.
    Alcendor RR, Kirshenbaum LA, Imai S, Vatner SF, Sadoshima J.
    Circ Res; 2004 Nov 12; 95(10):971-80. PubMed ID: 15486319
    [Abstract] [Full Text] [Related]

  • 17. MS275 enhances cytotoxicity induced by 5-fluorouracil in the colorectal cancer cells.
    Flis S, Gnyszka A, Flis K, Spławiński J.
    Eur J Pharmacol; 2010 Feb 10; 627(1-3):26-32. PubMed ID: 19853597
    [Abstract] [Full Text] [Related]

  • 18. Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.
    Ford J, Jiang M, Milner J.
    Cancer Res; 2005 Nov 15; 65(22):10457-63. PubMed ID: 16288037
    [Abstract] [Full Text] [Related]

  • 19. High expression of the longevity gene product SIRT1 and apoptosis induction by sirtinol in adult T-cell leukemia cells.
    Kozako T, Aikawa A, Shoji T, Fujimoto T, Yoshimitsu M, Shirasawa S, Tanaka H, Honda S, Shimeno H, Arima N, Soeda S.
    Int J Cancer; 2012 Nov 01; 131(9):2044-55. PubMed ID: 22322739
    [Abstract] [Full Text] [Related]

  • 20. Characterization of sirtuin inhibitors in nematodes expressing a muscular dystrophy protein reveals muscle cell and behavioral protection by specific sirtinol analogues.
    Pasco MY, Rotili D, Altucci L, Farina F, Rouleau GA, Mai A, Néri C.
    J Med Chem; 2010 Feb 11; 53(3):1407-11. PubMed ID: 20041717
    [Abstract] [Full Text] [Related]

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