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Journal Abstract Search

373 related items for PubMed ID: 20813865

  • 1. SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction.
    Yang SS, Lo YF, Wu CC, Lin SW, Yeh CJ, Chu P, Sytwu HK, Uchida S, Sasaki S, Lin SH.
    J Am Soc Nephrol; 2010 Nov; 21(11):1868-77. PubMed ID: 20813865
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  • 6. Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.
    Kikuchi E, Mori T, Zeniya M, Isobe K, Ishigami-Yuasa M, Fujii S, Kagechika H, Ishihara T, Mizushima T, Sasaki S, Sohara E, Rai T, Uchida S.
    J Am Soc Nephrol; 2015 Jul; 26(7):1525-36. PubMed ID: 25377078
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  • 7. SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner.
    Grimm PR, Taneja TK, Liu J, Coleman R, Chen YY, Delpire E, Wade JB, Welling PA.
    J Biol Chem; 2012 Nov 02; 287(45):37673-90. PubMed ID: 22977235
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  • 8. SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.
    Chu PY, Cheng CJ, Wu YC, Fang YW, Chau T, Uchida S, Sasaki S, Yang SS, Lin SH.
    PLoS One; 2013 Nov 02; 8(9):e72969. PubMed ID: 24039833
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  • 9. SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.
    Ferdaus MZ, Barber KW, López-Cayuqueo KI, Terker AS, Argaiz ER, Gassaway BM, Chambrey R, Gamba G, Rinehart J, McCormick JA.
    J Physiol; 2016 Sep 01; 594(17):4945-66. PubMed ID: 27068441
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  • 12. Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
    Vitari AC, Thastrup J, Rafiqi FH, Deak M, Morrice NA, Karlsson HK, Alessi DR.
    Biochem J; 2006 Jul 01; 397(1):223-31. PubMed ID: 16669787
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  • 13. WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.
    Bergaya S, Faure S, Baudrie V, Rio M, Escoubet B, Bonnin P, Henrion D, Loirand G, Achard JM, Jeunemaitre X, Hadchouel J.
    Hypertension; 2011 Sep 01; 58(3):439-45. PubMed ID: 21768522
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  • 14. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.
    Thastrup JO, Rafiqi FH, Vitari AC, Pozo-Guisado E, Deak M, Mehellou Y, Alessi DR.
    Biochem J; 2012 Jan 01; 441(1):325-37. PubMed ID: 22032326
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  • 15. Role of the WNK-activated SPAK kinase in regulating blood pressure.
    Rafiqi FH, Zuber AM, Glover M, Richardson C, Fleming S, Jovanović S, Jovanović A, O'Shaughnessy KM, Alessi DR.
    EMBO Mol Med; 2010 Feb 01; 2(2):63-75. PubMed ID: 20091762
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  • 16. Chronic Metabolic Acidosis Activates Renal Tubular Sodium Chloride Cotransporter through Angiotension II-dependent WNK4-SPAK Phosphorylation Pathway.
    Fang YW, Yang SS, Cheng CJ, Tseng MH, Hsu HM, Lin SH.
    Sci Rep; 2016 Jan 05; 6():18360. PubMed ID: 26728390
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  • 17. SPAK differentially mediates vasopressin effects on sodium cotransporters.
    Saritas T, Borschewski A, McCormick JA, Paliege A, Dathe C, Uchida S, Terker A, Himmerkus N, Bleich M, Demaretz S, Laghmani K, Delpire E, Ellison DH, Bachmann S, Mutig K.
    J Am Soc Nephrol; 2013 Feb 05; 24(3):407-18. PubMed ID: 23393317
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  • 18. Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models.
    Liu Z, Xie J, Wu T, Truong T, Auchus RJ, Huang CL.
    Hum Mol Genet; 2011 Mar 01; 20(5):855-66. PubMed ID: 21131289
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  • 19. Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).
    Piechotta K, Lu J, Delpire E.
    J Biol Chem; 2002 Dec 27; 277(52):50812-9. PubMed ID: 12386165
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  • 20. Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin II.
    Zeniya M, Sohara E, Kita S, Iwamoto T, Susa K, Mori T, Oi K, Chiga M, Takahashi D, Yang SS, Lin SH, Rai T, Sasaki S, Uchida S.
    Hypertension; 2013 Nov 27; 62(5):872-8. PubMed ID: 24019400
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