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Journal Abstract Search

869 related items for PubMed ID: 20817518

  • 1. Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.
    Korabecny J, Musilek K, Holas O, Binder J, Zemek F, Marek J, Pohanka M, Opletalova V, Dohnal V, Kuca K.
    Bioorg Med Chem Lett; 2010 Oct 15; 20(20):6093-5. PubMed ID: 20817518
    [Abstract] [Full Text] [Related]

  • 2. 7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
    Korabecny J, Dolezal R, Cabelova P, Horova A, Hruba E, Ricny J, Sedlacek L, Nepovimova E, Spilovska K, Andrs M, Musilek K, Opletalova V, Sepsova V, Ripova D, Kuca K.
    Eur J Med Chem; 2014 Jul 23; 82():426-38. PubMed ID: 24929293
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease.
    Hamulakova S, Janovec L, Hrabinova M, Kristian P, Kuca K, Banasova M, Imrich J.
    Eur J Med Chem; 2012 Sep 23; 55():23-31. PubMed ID: 22818849
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W, Li YP, He Y, Huang SL, Li D, Gu LQ, Huang ZS.
    Eur J Med Chem; 2011 Jun 23; 46(6):2609-16. PubMed ID: 21497959
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Shao D, Zou C, Luo C, Tang X, Li Y.
    Bioorg Med Chem Lett; 2004 Sep 20; 14(18):4639-42. PubMed ID: 15324879
    [Abstract] [Full Text] [Related]

  • 6. Novel tacrine analogs as potential cholinesterase inhibitors in Alzheimer's disease.
    El-Malah A, Gedawy EM, Kassab AE, Salam RM.
    Arch Pharm (Weinheim); 2014 Feb 20; 347(2):96-103. PubMed ID: 24343873
    [Abstract] [Full Text] [Related]

  • 7. Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
    Fang L, Kraus B, Lehmann J, Heilmann J, Zhang Y, Decker M.
    Bioorg Med Chem Lett; 2008 May 01; 18(9):2905-9. PubMed ID: 18406135
    [Abstract] [Full Text] [Related]

  • 8. Tacrine based human cholinesterase inhibitors: synthesis of peptidic-tethered derivatives and their effect on potency and selectivity.
    Butini S, Guarino E, Campiani G, Brindisi M, Coccone SS, Fiorini I, Novellino E, Belinskaya T, Saxena A, Gemma S.
    Bioorg Med Chem Lett; 2008 Oct 01; 18(19):5213-6. PubMed ID: 18786825
    [Abstract] [Full Text] [Related]

  • 9. 7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.
    Spilovska K, Korabecny J, Kral J, Horova A, Musilek K, Soukup O, Drtinova L, Gazova Z, Siposova K, Kuca K.
    Molecules; 2013 Feb 20; 18(2):2397-418. PubMed ID: 23429378
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.
    Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ.
    J Med Chem; 1999 Aug 26; 42(17):3227-42. PubMed ID: 10464010
    [Abstract] [Full Text] [Related]

  • 11. New tacrine-hydrazinonicotinamide hybrids as acetylcholinesterase inhibitors of potential interest for the early diagnostics of Alzheimer's disease.
    Szymański P, Zurek E, Mikiciuk-Olasik E.
    Pharmazie; 2006 Apr 26; 61(4):269-73. PubMed ID: 16649535
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates.
    Fang L, Appenroth D, Decker M, Kiehntopf M, Roegler C, Deufel T, Fleck C, Peng S, Zhang Y, Lehmann J.
    J Med Chem; 2008 Feb 28; 51(4):713-6. PubMed ID: 18232655
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and cholinesterase inhibitory activity of 6-, 7-methoxy-(and hydroxy-) tacrine derivatives.
    Del Giudice MR, Borioni A, Mustazza C, Gatta F, Meneguz A, Volpe MT.
    Farmaco; 1996 Nov 28; 51(11):693-8. PubMed ID: 9035375
    [Abstract] [Full Text] [Related]

  • 14. Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
    Camps P, Formosa X, Galdeano C, Muñoz-Torrero D, Ramírez L, Gómez E, Isambert N, Lavilla R, Badia A, Clos MV, Bartolini M, Mancini F, Andrisano V, Arce MP, Rodríguez-Franco MI, Huertas O, Dafni T, Luque FJ.
    J Med Chem; 2009 Sep 10; 52(17):5365-79. PubMed ID: 19663388
    [Abstract] [Full Text] [Related]

  • 15. The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
    Hepnarova V, Korabecny J, Matouskova L, Jost P, Muckova L, Hrabinova M, Vykoukalova N, Kerhartova M, Kucera T, Dolezal R, Nepovimova E, Spilovska K, Mezeiova E, Pham NL, Jun D, Staud F, Kaping D, Kuca K, Soukup O.
    Eur J Med Chem; 2018 Apr 25; 150():292-306. PubMed ID: 29533874
    [Abstract] [Full Text] [Related]

  • 16. Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
    Tang H, Zhao LZ, Zhao HT, Huang SL, Zhong SM, Qin JK, Chen ZF, Huang ZS, Liang H.
    Eur J Med Chem; 2011 Oct 25; 46(10):4970-9. PubMed ID: 21871694
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of new 2-benzoxazolinone derivatives as potential cholinesterase inhibitors for therapy of alzheimer's disease.
    Szymański P, Janik A, Zurek E, Mikiciuk-Olasik E.
    Pharmazie; 2011 Jun 25; 66(6):399-403. PubMed ID: 21699076
    [Abstract] [Full Text] [Related]

  • 18. Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment.
    Musilek K, Komloova M, Holas O, Hrabinova M, Pohanka M, Dohnal V, Nachon F, Dolezal M, Kuca K.
    Eur J Med Chem; 2011 Feb 25; 46(2):811-8. PubMed ID: 21236521
    [Abstract] [Full Text] [Related]

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  • 20. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.
    Fernández-Bachiller MI, Pérez C, Monjas L, Rademann J, Rodríguez-Franco MI.
    J Med Chem; 2012 Feb 09; 55(3):1303-17. PubMed ID: 22243648
    [Abstract] [Full Text] [Related]

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