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Journal Abstract Search

528 related items for PubMed ID: 2082193

  • 1. Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
    Sakurai A, Miyamoto T, Refetoff S, DeGroot LJ.
    Mol Endocrinol; 1990 Dec; 4(12):1988-94. PubMed ID: 2082193
    [Abstract] [Full Text] [Related]

  • 2. Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone.
    Takeda T, Suzuki S, Liu RT, DeGroot LJ.
    J Clin Endocrinol Metab; 1995 Jul; 80(7):2033-40. PubMed ID: 7608251
    [Abstract] [Full Text] [Related]

  • 3. Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.
    Meier CA, Dickstein BM, Ashizawa K, McClaskey JH, Muchmore P, Ransom SC, Menke JB, Hao EH, Usala SJ, Bercu BB.
    Mol Endocrinol; 1992 Feb; 6(2):248-58. PubMed ID: 1569968
    [Abstract] [Full Text] [Related]

  • 4. Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
    Zavacki AM, Harney JW, Brent GA, Larsen PR.
    Mol Endocrinol; 1993 Oct; 7(10):1319-30. PubMed ID: 8264663
    [Abstract] [Full Text] [Related]

  • 5. Two thyroid hormone response elements are present in the promoter of human thyroid hormone receptor beta 1.
    Suzuki S, Miyamoto T, Opsahl A, Sakurai A, DeGroot LJ.
    Mol Endocrinol; 1994 Mar; 8(3):305-14. PubMed ID: 8015548
    [Abstract] [Full Text] [Related]

  • 6. The function of retinoid X receptors on negative thyroid hormone response elements.
    Takeda T, Nagasawa T, Miyamoto T, Hashizume K, DeGroot LJ.
    Mol Cell Endocrinol; 1997 Apr 04; 128(1-2):85-96. PubMed ID: 9140079
    [Abstract] [Full Text] [Related]

  • 7. Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
    Meier CA, Parkison C, Chen A, Ashizawa K, Meier-Heusler SC, Muchmore P, Cheng SY, Weintraub BD.
    J Clin Invest; 1993 Oct 04; 92(4):1986-93. PubMed ID: 8408652
    [Abstract] [Full Text] [Related]

  • 8. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ, Ortiz MA, Pfahl M.
    Mol Endocrinol; 1995 Nov 04; 9(11):1533-48. PubMed ID: 8584031
    [Abstract] [Full Text] [Related]

  • 9. High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociation.
    Miyamoto T, Suzuki S, DeGroot LJ.
    Mol Endocrinol; 1993 Feb 04; 7(2):224-31. PubMed ID: 8469235
    [Abstract] [Full Text] [Related]

  • 10. Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone beta 1-receptors: the important role of the wild-type/mutant receptor heterodimer.
    Zhu XG, Yu CL, McPhie P, Wong R, Cheng SY.
    Endocrinology; 1996 Feb 04; 137(2):712-21. PubMed ID: 8593822
    [Abstract] [Full Text] [Related]

  • 11. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.
    Ng L, Forrest D, Haugen BR, Wood WM, Curran T.
    Mol Endocrinol; 1995 Sep 04; 9(9):1202-13. PubMed ID: 7491112
    [Abstract] [Full Text] [Related]

  • 12. Negative and positive transcriptional regulation by thyroid hormone receptor isoforms.
    Rentoumis A, Chatterjee VK, Madison LD, Datta S, Gallagher GD, Degroot LJ, Jameson JL.
    Mol Endocrinol; 1990 Oct 04; 4(10):1522-31. PubMed ID: 2284000
    [Abstract] [Full Text] [Related]

  • 13. Amino acid substitutions of thyroid hormone receptor-beta at codon 435 with resistance to thyroid hormone selectively alter homodimer formation.
    Nomura Y, Nagaya T, Tsukaguchi H, Takamatsu J, Seo H.
    Endocrinology; 1996 Oct 04; 137(10):4082-6. PubMed ID: 8828460
    [Abstract] [Full Text] [Related]

  • 14. Identification of naturally occurring dominant negative mutants of thyroid hormone alpha 1 and beta 1 receptors in a human hepatocellular carcinoma cell line.
    Lin KH, Zhu XG, Shieh HY, Hsu HC, Chen ST, McPhie P, Cheng SY.
    Endocrinology; 1996 Oct 04; 137(10):4073-81. PubMed ID: 8828459
    [Abstract] [Full Text] [Related]

  • 15. Difference in dominant negative activities between mutant thyroid hormone receptors alpha1 and beta1 with an identical truncation in the extreme carboxyl-terminal tau4 domain.
    Nishiyama K, Andoh S, Kitahara A, Natsume H, Mikami T, Genma R, Nakamura H.
    Mol Cell Endocrinol; 1998 Mar 16; 138(1-2):95-104. PubMed ID: 9685218
    [Abstract] [Full Text] [Related]

  • 16. New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.
    Yen PM, Sugawara A, Refetoff S, Chin WW.
    J Clin Invest; 1992 Nov 16; 90(5):1825-31. PubMed ID: 1430208
    [Abstract] [Full Text] [Related]

  • 17. Dominant-negative mutant thyroid hormone receptors prevent transcription from Xenopus thyroid hormone receptor beta gene promoter in response to thyroid hormone in Xenopus tadpoles in vivo.
    Ulisse S, Esslemont G, Baker BS, Krishna V, Chatterjee K, Tata JR.
    Proc Natl Acad Sci U S A; 1996 Feb 06; 93(3):1205-9. PubMed ID: 8577741
    [Abstract] [Full Text] [Related]

  • 18. Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbA alpha 2 and peroxisome proliferator-activated receptor: evidence for different mechanisms of inhibition.
    Meier-Heusler SC, Zhu X, Juge-Aubry C, Pernin A, Burger AG, Cheng SY, Meier CA.
    Mol Cell Endocrinol; 1995 Jan 06; 107(1):55-66. PubMed ID: 7796935
    [Abstract] [Full Text] [Related]

  • 19. Ligand (T3) dependent and independent effects of thyroid hormone receptors upon human TRH gene transcription in neuroblastoma cells.
    Feng P, Li QL, Satoh T, Wilber JF.
    Biochem Biophys Res Commun; 1994 Apr 15; 200(1):171-7. PubMed ID: 8166684
    [Abstract] [Full Text] [Related]

  • 20. Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
    Wong R, Zhu XG, Pineda MA, Cheng SY, Weintraub BD.
    Mol Med; 1995 Mar 15; 1(3):306-19. PubMed ID: 8529109
    [Abstract] [Full Text] [Related]

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