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318 related items for PubMed ID: 20823249

  • 1. Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline.
    Pulvers JN, Bryk J, Fish JL, Wilsch-Bräuninger M, Arai Y, Schreier D, Naumann R, Helppi J, Habermann B, Vogt J, Nitsch R, Tóth A, Enard W, Pääbo S, Huttner WB.
    Proc Natl Acad Sci U S A; 2010 Sep 21; 107(38):16595-600. PubMed ID: 20823249
    [Abstract] [Full Text] [Related]

  • 2. Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.
    Johnson MB, Sun X, Kodani A, Borges-Monroy R, Girskis KM, Ryu SC, Wang PP, Patel K, Gonzalez DM, Woo YM, Yan Z, Liang B, Smith RS, Chatterjee M, Coman D, Papademetris X, Staib LH, Hyder F, Mandeville JB, Grant PE, Im K, Kwak H, Engelhardt JF, Walsh CA, Bae BI.
    Nature; 2018 Apr 21; 556(7701):370-375. PubMed ID: 29643508
    [Abstract] [Full Text] [Related]

  • 3. Loss of abnormal spindle-like, microcephaly-associated (Aspm) disrupts female folliculogenesis in mice during maturation and aging.
    Mori M, Tando S, Ogi H, Tonosaki M, Yaoi T, Fujimori A, Itoh K.
    Reprod Biol; 2022 Sep 21; 22(3):100673. PubMed ID: 35901620
    [Abstract] [Full Text] [Related]

  • 4. Disruption of Aspm causes microcephaly with abnormal neuronal differentiation.
    Fujimori A, Itoh K, Goto S, Hirakawa H, Wang B, Kokubo T, Kito S, Tsukamoto S, Fushiki S.
    Brain Dev; 2014 Sep 21; 36(8):661-9. PubMed ID: 24220505
    [Abstract] [Full Text] [Related]

  • 5. ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.
    Gai M, Bianchi FT, Vagnoni C, Vernì F, Bonaccorsi S, Pasquero S, Berto GE, Sgrò F, Chiotto AM, Annaratone L, Sapino A, Bergo A, Landsberger N, Bond J, Huttner WB, Di Cunto F.
    EMBO Rep; 2016 Oct 21; 17(10):1396-1409. PubMed ID: 27562601
    [Abstract] [Full Text] [Related]

  • 6. Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors.
    Lizarraga SB, Margossian SP, Harris MH, Campagna DR, Han AP, Blevins S, Mudbhary R, Barker JE, Walsh CA, Fleming MD.
    Development; 2010 Jun 21; 137(11):1907-17. PubMed ID: 20460369
    [Abstract] [Full Text] [Related]

  • 7. Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.
    Jayaraman D, Kodani A, Gonzalez DM, Mancias JD, Mochida GH, Vagnoni C, Johnson J, Krogan N, Harper JW, Reiter JF, Yu TW, Bae BI, Walsh CA.
    Neuron; 2016 Nov 23; 92(4):813-828. PubMed ID: 27974163
    [Abstract] [Full Text] [Related]

  • 8. The Multiple Mitotic Roles of the ASPM Orthologous Proteins: Insight into the Etiology of ASPM-Dependent Microcephaly.
    Razuvaeva AV, Graziadio L, Palumbo V, Pavlova GA, Popova JV, Pindyurin AV, Bonaccorsi S, Somma MP, Gatti M.
    Cells; 2023 Mar 16; 12(6):. PubMed ID: 36980263
    [Abstract] [Full Text] [Related]

  • 9. Human ASPM participates in spindle organisation, spindle orientation and cytokinesis.
    Higgins J, Midgley C, Bergh AM, Bell SM, Askham JM, Roberts E, Binns RK, Sharif SM, Bennett C, Glover DM, Woods CG, Morrison EE, Bond J.
    BMC Cell Biol; 2010 Nov 02; 11():85. PubMed ID: 21044324
    [Abstract] [Full Text] [Related]

  • 10. Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.
    Fish JL, Kosodo Y, Enard W, Pääbo S, Huttner WB.
    Proc Natl Acad Sci U S A; 2006 Jul 05; 103(27):10438-10443. PubMed ID: 16798874
    [Abstract] [Full Text] [Related]

  • 11. Autosomal recessive primary microcephaly due to ASPM mutations: An update.
    Létard P, Drunat S, Vial Y, Duerinckx S, Ernault A, Amram D, Arpin S, Bertoli M, Busa T, Ceulemans B, Desir J, Doco-Fenzy M, Elalaoui SC, Devriendt K, Faivre L, Francannet C, Geneviève D, Gérard M, Gitiaux C, Julia S, Lebon S, Lubala T, Mathieu-Dramard M, Maurey H, Metreau J, Nasserereddine S, Nizon M, Pierquin G, Pouvreau N, Rivier-Ringenbach C, Rossi M, Schaefer E, Sefiani A, Sigaudy S, Sznajer Y, Tunca Y, Guilmin Crepon S, Alberti C, Elmaleh-Bergès M, Benzacken B, Wollnick B, Woods CG, Rauch A, Abramowicz M, El Ghouzzi V, Gressens P, Verloes A, Passemard S.
    Hum Mutat; 2018 Mar 05; 39(3):319-332. PubMed ID: 29243349
    [Abstract] [Full Text] [Related]

  • 12. Molecular and phenotypic spectrum of ASPM-related primary microcephaly: Identification of eight novel mutations.
    Abdel-Hamid MS, Ismail MF, Darwish HA, Effat LK, Zaki MS, Abdel-Salam GM.
    Am J Med Genet A; 2016 Aug 05; 170(8):2133-40. PubMed ID: 27250695
    [Abstract] [Full Text] [Related]

  • 13. A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.
    Garrett L, Chang YJ, Niedermeier KM, Heermann T, Enard W, Fuchs H, Gailus-Durner V, Angelis MH, Huttner WB, Wurst W, Hölter SM.
    Transl Psychiatry; 2020 Feb 13; 10(1):66. PubMed ID: 32066665
    [Abstract] [Full Text] [Related]

  • 14. Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2.
    Tungadi EA, Ito A, Kiyomitsu T, Goshima G.
    J Cell Sci; 2017 Nov 01; 130(21):3676-3684. PubMed ID: 28883092
    [Abstract] [Full Text] [Related]

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  • 16. Protein-truncating mutations in ASPM cause variable reduction in brain size.
    Bond J, Scott S, Hampshire DJ, Springell K, Corry P, Abramowicz MJ, Mochida GH, Hennekam RC, Maher ER, Fryns JP, Alswaid A, Jafri H, Rashid Y, Mubaidin A, Walsh CA, Roberts E, Woods CG.
    Am J Hum Genet; 2003 Nov 01; 73(5):1170-7. PubMed ID: 14574646
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  • 18. Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion.
    Kouprina N, Pavlicek A, Mochida GH, Solomon G, Gersch W, Yoon YH, Collura R, Ruvolo M, Barrett JC, Woods CG, Walsh CA, Jurka J, Larionov V.
    PLoS Biol; 2004 May 01; 2(5):E126. PubMed ID: 15045028
    [Abstract] [Full Text] [Related]

  • 19. Genetic basis of brain size evolution in cetaceans: insights from adaptive evolution of seven primary microcephaly (MCPH) genes.
    Xu S, Sun X, Niu X, Zhang Z, Tian R, Ren W, Zhou K, Yang G.
    BMC Evol Biol; 2017 Aug 29; 17(1):206. PubMed ID: 28851290
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