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Journal Abstract Search

227 related items for PubMed ID: 20830700

  • 21. Studies on the chemical reactivity of 2-phenylpropionic acid 1-O-acyl glucuronide and S-acyl-CoA thioester metabolites.
    Li C, Benet LZ, Grillo MP.
    Chem Res Toxicol; 2002 Oct; 15(10):1309-17. PubMed ID: 12387630
    [Abstract] [Full Text] [Related]

  • 22. Structure-activity relationships for the degradation reaction of 1-beta-O-acyl glucuronides. Part 3: Electronic and steric descriptors predicting the reactivity of aralkyl carboxylic acid 1-beta-O-acyl glucuronides.
    Baba A, Yoshioka T.
    Chem Res Toxicol; 2009 Dec; 22(12):1998-2008. PubMed ID: 19902937
    [Abstract] [Full Text] [Related]

  • 23. The influence of physicochemical properties on the reactivity and stability of acyl glucuronides †.
    Camilleri P, Buch A, Soldo B, Hutt AJ.
    Xenobiotica; 2018 Sep; 48(9):958-972. PubMed ID: 28967291
    [Abstract] [Full Text] [Related]

  • 24. NMR and QSAR studies on the transacylation reactivity of model 1beta-O-acyl glucuronides. I: design, synthesis and degradation rate measurement.
    Vanderhoeven SJ, Lindon JC, Troke J, Tranter GE, Wilson ID, Nicholson JK.
    Xenobiotica; 2004 Jan; 34(1):73-85. PubMed ID: 15729774
    [Abstract] [Full Text] [Related]

  • 25. Development of an in vitro screening model for the biosynthesis of acyl glucuronide metabolites and the assessment of their reactivity toward human serum albumin.
    Bolze S, Bromet N, Gay-Feutry C, Massiere F, Boulieu R, Hulot T.
    Drug Metab Dispos; 2002 Apr; 30(4):404-13. PubMed ID: 11901094
    [Abstract] [Full Text] [Related]

  • 26. Disposition and covalent binding of diflunisal and diflunisal acyl glucuronide in the isolated perfused rat liver.
    Wang M, Dickinson RG.
    Drug Metab Dispos; 1998 Feb; 26(2):98-104. PubMed ID: 9456294
    [Abstract] [Full Text] [Related]

  • 27. Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly.
    Castillo M, Lam YW, Dooley MA, Stahl E, Smith PC.
    Clin Pharmacol Ther; 1995 Jun; 57(6):636-44. PubMed ID: 7781263
    [Abstract] [Full Text] [Related]

  • 28. NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues.
    Johnson CH, Wilson ID, Harding JR, Stachulski AV, Iddon L, Nicholson JK, Lindon JC.
    Anal Chem; 2007 Nov 15; 79(22):8720-7. PubMed ID: 17944439
    [Abstract] [Full Text] [Related]

  • 29. Covalent binding of acidic drugs via reactive intermediates: detection of benoxaprofen and flunoxaprofen protein adducts in biological material.
    Dahms M, Spahn-Langguth H.
    Pharmazie; 1996 Nov 15; 51(11):874-81. PubMed ID: 8985978
    [Abstract] [Full Text] [Related]

  • 30. Chemistry and reactivity of acyl glucuronides.
    Stachulski AV.
    Curr Drug Metab; 2011 Mar 15; 12(3):215-21. PubMed ID: 20946098
    [Abstract] [Full Text] [Related]

  • 31. Structural characterization of anti-HIV drug candidate PA-457 [3-O-(3',3'-dimethylsuccinyl)-betulinic acid] and its acyl glucuronides in rat bile and evaluation of in vitro stability in human and animal liver microsomes and plasma.
    Wen Z, Stern ST, Martin DE, Lee KH, Smith PC.
    Drug Metab Dispos; 2006 Sep 15; 34(9):1436-42. PubMed ID: 16751262
    [Abstract] [Full Text] [Related]

  • 32. Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac.
    Kenny JR, Maggs JL, Meng X, Sinnott D, Clarke SE, Park BK, Stachulski AV.
    J Med Chem; 2004 May 20; 47(11):2816-25. PubMed ID: 15139759
    [Abstract] [Full Text] [Related]

  • 33. Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry.
    Ma S, Subramanian R.
    J Mass Spectrom; 2006 Sep 20; 41(9):1121-39. PubMed ID: 16967439
    [Abstract] [Full Text] [Related]

  • 34. Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes.
    Grillo MP, Hua F, Knutson CG, Ware JA, Li C.
    Chem Res Toxicol; 2003 Nov 20; 16(11):1410-7. PubMed ID: 14615966
    [Abstract] [Full Text] [Related]

  • 35. Iso-glucuronides.
    Dickinson RG.
    Curr Drug Metab; 2011 Mar 20; 12(3):222-8. PubMed ID: 21395535
    [Abstract] [Full Text] [Related]

  • 36. Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions.
    Ritter JK.
    Chem Biol Interact; 2000 Dec 01; 129(1-2):171-93. PubMed ID: 11154740
    [Abstract] [Full Text] [Related]

  • 37. Metabolism of xenobiotic carboxylic acids: focus on coenzyme A conjugation, reactivity, and interference with lipid metabolism.
    Darnell M, Weidolf L.
    Chem Res Toxicol; 2013 Aug 19; 26(8):1139-55. PubMed ID: 23790050
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  • 38. Glycerolysis of acyl glucuronides as an artifact of in vitro drug metabolism incubations.
    Obach RS.
    Drug Metab Dispos; 2009 Aug 19; 37(8):1581-6. PubMed ID: 19439485
    [Abstract] [Full Text] [Related]

  • 39. Reactivity of gemfibrozil 1-o-beta-acyl glucuronide. Pharmacokinetics of covalently bound gemfibrozil-protein adducts in rats.
    Sallustio BC, Foster DJ.
    Drug Metab Dispos; 1995 Sep 19; 23(9):892-9. PubMed ID: 8565777
    [Abstract] [Full Text] [Related]

  • 40. In vitro and in vivo irreversible plasma protein binding of beclobric acid enantiomers.
    Mayer S, Mutschler E, Benet LZ, Sphahn-Langguth H.
    Chirality; 1993 Sep 19; 5(3):120-5. PubMed ID: 8338721
    [Abstract] [Full Text] [Related]

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