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274 related items for PubMed ID: 20837137

  • 1. TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation.
    Mao R, Fan Y, Mou Y, Zhang H, Fu S, Yang J.
    Cell Signal; 2011 Jan; 23(1):222-7. PubMed ID: 20837137
    [Abstract] [Full Text] [Related]

  • 2. Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation.
    Fan Y, Yu Y, Shi Y, Sun W, Xie M, Ge N, Mao R, Chang A, Xu G, Schneider MD, Zhang H, Fu S, Qin J, Yang J.
    J Biol Chem; 2010 Feb 19; 285(8):5347-60. PubMed ID: 20038579
    [Abstract] [Full Text] [Related]

  • 3. TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation.
    Fan Y, Yu Y, Mao R, Zhang H, Yang J.
    Cell Signal; 2011 Apr 19; 23(4):660-5. PubMed ID: 21130870
    [Abstract] [Full Text] [Related]

  • 4. Polyubiquitination of Transforming Growth Factor β-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4-mediated JNK and p38 MAPK Activation.
    Chen IT, Hsu PH, Hsu WC, Chen NJ, Tseng PH.
    Sci Rep; 2015 Jul 20; 5():12300. PubMed ID: 26189595
    [Abstract] [Full Text] [Related]

  • 5. The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner.
    Sorrentino A, Thakur N, Grimsby S, Marcusson A, von Bulow V, Schuster N, Zhang S, Heldin CH, Landström M.
    Nat Cell Biol; 2008 Oct 20; 10(10):1199-207. PubMed ID: 18758450
    [Abstract] [Full Text] [Related]

  • 6. TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta.
    Yamashita M, Fatyol K, Jin C, Wang X, Liu Z, Zhang YE.
    Mol Cell; 2008 Sep 26; 31(6):918-24. PubMed ID: 18922473
    [Abstract] [Full Text] [Related]

  • 7. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.
    Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, Lee KY, Bussey C, Steckel M, Tanaka N, Yamada G, Akira S, Matsumoto K, Ghosh S.
    Genes Dev; 2005 Nov 15; 19(22):2668-81. PubMed ID: 16260493
    [Abstract] [Full Text] [Related]

  • 8. Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation.
    Arsura M, Panta GR, Bilyeu JD, Cavin LG, Sovak MA, Oliver AA, Factor V, Heuchel R, Mercurio F, Thorgeirsson SS, Sonenshein GE.
    Oncogene; 2003 Jan 23; 22(3):412-25. PubMed ID: 12545162
    [Abstract] [Full Text] [Related]

  • 9. TAK1 ubiquitination regulates doxorubicin-induced NF-κB activation.
    Liang L, Fan Y, Cheng J, Cheng D, Zhao Y, Cao B, Ma L, An L, Jia W, Su X, Yang J, Zhang H.
    Cell Signal; 2013 Jan 23; 25(1):247-54. PubMed ID: 22981905
    [Abstract] [Full Text] [Related]

  • 10. Endotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expression.
    Xiong Y, Qiu F, Piao W, Song C, Wahl LM, Medvedev AE.
    J Biol Chem; 2011 Mar 11; 286(10):7905-7916. PubMed ID: 21220427
    [Abstract] [Full Text] [Related]

  • 11. Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression.
    Yu Y, Ge N, Xie M, Sun W, Burlingame S, Pass AK, Nuchtern JG, Zhang D, Fu S, Schneider MD, Fan J, Yang J.
    J Biol Chem; 2008 Sep 05; 283(36):24497-505. PubMed ID: 18617512
    [Abstract] [Full Text] [Related]

  • 12. Activation of TAK1 by Sef-S induces apoptosis in 293T cells.
    Sun X, Wang Y, Yang S, Ren F, Xia Y, Chang Z.
    Cell Signal; 2013 Oct 05; 25(10):2039-46. PubMed ID: 23770285
    [Abstract] [Full Text] [Related]

  • 13. Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6.
    Jung SM, Lee JH, Park J, Oh YS, Lee SK, Park JS, Lee YS, Kim JH, Lee JY, Bae YS, Koo SH, Kim SJ, Park SH.
    Nat Commun; 2013 Oct 05; 4():2562. PubMed ID: 24096742
    [Abstract] [Full Text] [Related]

  • 14. Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli.
    Hamidi A, von Bulow V, Hamidi R, Winssinger N, Barluenga S, Heldin CH, Landström M.
    J Biol Chem; 2012 Jan 02; 287(1):123-133. PubMed ID: 22069318
    [Abstract] [Full Text] [Related]

  • 15. Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.
    Matta H, Gopalakrishnan R, Graham C, Tolani B, Khanna A, Yi H, Suo Y, Chaudhary PM.
    PLoS One; 2012 Jan 02; 7(5):e36601. PubMed ID: 22590573
    [Abstract] [Full Text] [Related]

  • 16. TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd.
    Morlon A, Munnich A, Smahi A.
    Hum Mol Genet; 2005 Dec 01; 14(23):3751-7. PubMed ID: 16251197
    [Abstract] [Full Text] [Related]

  • 17. X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1).
    Kaur S, Wang F, Venkatraman M, Arsura M.
    J Biol Chem; 2005 Nov 18; 280(46):38599-608. PubMed ID: 16157589
    [Abstract] [Full Text] [Related]

  • 18. ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction.
    Mochida Y, Takeda K, Saitoh M, Nishitoh H, Amagasa T, Ninomiya-Tsuji J, Matsumoto K, Ichijo H.
    J Biol Chem; 2000 Oct 20; 275(42):32747-52. PubMed ID: 10921914
    [Abstract] [Full Text] [Related]

  • 19. Polyubiquitination events mediate polymethylmethacrylate (PMMA) particle activation of NF-kappaB pathway.
    Yamanaka Y, Karuppaiah K, Abu-Amer Y.
    J Biol Chem; 2011 Jul 08; 286(27):23735-41. PubMed ID: 21566132
    [Abstract] [Full Text] [Related]

  • 20. TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB.
    Lee SW, Han SI, Kim HH, Lee ZH.
    J Biochem Mol Biol; 2002 Jul 31; 35(4):371-6. PubMed ID: 12296995
    [Abstract] [Full Text] [Related]

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