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Journal Abstract Search

238 related items for PubMed ID: 20855037

  • 21. The discovery and development of boceprevir.
    Rotella DP.
    Expert Opin Drug Discov; 2013 Nov; 8(11):1439-47. PubMed ID: 24079543
    [Abstract] [Full Text] [Related]

  • 22. Novel potent inhibitors of hepatitis C virus (HCV) NS3 protease with cyclic sulfonyl P3 cappings.
    Chen KX, Vibulbhan B, Yang W, Nair LG, Tong X, Cheng KC, Njoroge FG.
    Bioorg Med Chem Lett; 2009 Feb 15; 19(4):1105-9. PubMed ID: 19168351
    [Abstract] [Full Text] [Related]

  • 23. Synthesis of BILN 2061, an HCV NS3 protease inhibitor with proven antiviral effect in humans.
    Faucher AM, Bailey MD, Beaulieu PL, Brochu C, Duceppe JS, Ferland JM, Ghiro E, Gorys V, Halmos T, Kawai SH, Poirier M, Simoneau B, Tsantrizos YS, Llinàs-Brunet M.
    Org Lett; 2004 Aug 19; 6(17):2901-4. PubMed ID: 15330643
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  • 25. Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design.
    Venkatraman S, Njoroge FG, Girijavallabhan VM, Madison VS, Yao NH, Prongay AJ, Butkiewicz N, Pichardo J.
    J Med Chem; 2005 Aug 11; 48(16):5088-91. PubMed ID: 16078825
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  • 27. Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease.
    Duan D, Li Z, Luo H, Zhang W, Chen L, Xu X.
    Bioorg Med Chem Lett; 2004 Dec 20; 14(24):6041-4. PubMed ID: 15546725
    [Abstract] [Full Text] [Related]

  • 28. Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles.
    Chen KX, Njoroge FG, Arasappan A, Venkatraman S, Vibulbhan B, Yang W, Parekh TN, Pichardo J, Prongay A, Cheng KC, Butkiewicz N, Yao N, Madison V, Girijavallabhan V.
    J Med Chem; 2006 Feb 09; 49(3):995-1005. PubMed ID: 16451065
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  • 30. Characterization of resistance mutations against HCV ketoamide protease inhibitors.
    Tong X, Bogen S, Chase R, Girijavallabhan V, Guo Z, Njoroge FG, Prongay A, Saksena A, Skelton A, Xia E, Ralston R.
    Antiviral Res; 2008 Mar 09; 77(3):177-85. PubMed ID: 18201776
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  • 32. Synthesis and antiviral activity of HCV NS3/4A peptidomimetic boronic acid inhibitors.
    Boloor A, Hanway D, Joshi M, Winn DT, Mendez G, Walls M, Wei P, Qian F, Zhang X, Zhang Y, Hepperle ME, Li X, Campbell DA, Betancort JM.
    Bioorg Med Chem Lett; 2009 Oct 01; 19(19):5708-11. PubMed ID: 19713109
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  • 35. Potent inhibitors of the hepatitis C virus NS3 protease: use of a novel P2 cyclopentane-derived template.
    Johansson PO, Bäck M, Kvarnström I, Jansson K, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B.
    Bioorg Med Chem; 2006 Aug 01; 14(15):5136-51. PubMed ID: 16675222
    [Abstract] [Full Text] [Related]

  • 36. Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.
    Ortqvist P, Peterson SD, Kerblom E, Gossas T, Sabnis YA, Fransson R, Lindeberg G, Helena Danielson U, Karlén A, Sandström A.
    Bioorg Med Chem; 2007 Feb 01; 15(3):1448-74. PubMed ID: 17113777
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  • 37.
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  • 38. Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease.
    Slater MJ, Amphlett EM, Andrews DM, Bamborough P, Carey SJ, Johnson MR, Jones PS, Mills G, Parry NR, Somers DO, Stewart AJ, Skarzynski T.
    Org Lett; 2003 Nov 27; 5(24):4627-30. PubMed ID: 14627400
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  • 40. Discovery of achiral inhibitors of the hepatitis C virus NS3 protease based on 2(1H)-pyrazinones.
    Ortqvist P, Gising J, Ehrenberg AE, Vema A, Borg A, Karlén A, Larhed M, Danielson UH, Sandström A.
    Bioorg Med Chem; 2010 Sep 01; 18(17):6512-25. PubMed ID: 20673728
    [Abstract] [Full Text] [Related]

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