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Journal Abstract Search


436 related items for PubMed ID: 20856197

  • 1. PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis.
    Bender A, Opel D, Naumann I, Kappler R, Friedman L, von Schweinitz D, Debatin KM, Fulda S.
    Oncogene; 2011 Jan 27; 30(4):494-503. PubMed ID: 20856197
    [Abstract] [Full Text] [Related]

  • 2. Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma.
    Opel D, Naumann I, Schneider M, Bertele D, Debatin KM, Fulda S.
    Clin Cancer Res; 2011 May 15; 17(10):3233-47. PubMed ID: 21355080
    [Abstract] [Full Text] [Related]

  • 3. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U, Hahn H, Fulda S.
    Oncotarget; 2015 Apr 20; 6(11):8722-35. PubMed ID: 25749378
    [Abstract] [Full Text] [Related]

  • 4. Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway.
    Naumann I, Kappler R, von Schweinitz D, Debatin KM, Fulda S.
    Clin Cancer Res; 2011 May 15; 17(10):3204-18. PubMed ID: 21459798
    [Abstract] [Full Text] [Related]

  • 5. PI3K Inhibitor Combined With Chemotherapy Can Enhance the Apoptosis of Neuroblastoma Cells In Vitro and In Vivo.
    Geng X, Xie L, Xing H.
    Technol Cancer Res Treat; 2016 Oct 15; 15(5):716-22. PubMed ID: 26224681
    [Abstract] [Full Text] [Related]

  • 6. Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer.
    Shankar S, Srivastava RK.
    Int J Oncol; 2007 Apr 15; 30(4):905-18. PubMed ID: 17332930
    [Abstract] [Full Text] [Related]

  • 7. Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis.
    Unterkircher T, Cristofanon S, Vellanki SH, Nonnenmacher L, Karpel-Massler G, Wirtz CR, Debatin KM, Fulda S.
    Clin Cancer Res; 2011 Jun 15; 17(12):4019-30. PubMed ID: 21525171
    [Abstract] [Full Text] [Related]

  • 8. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
    Guenther MK, Graab U, Fulda S.
    Cancer Lett; 2013 Sep 01; 337(2):200-9. PubMed ID: 23684925
    [Abstract] [Full Text] [Related]

  • 9. Histone deacetylase inhibitors prime medulloblastoma cells for chemotherapy-induced apoptosis by enhancing p53-dependent Bax activation.
    Häcker S, Karl S, Mader I, Cristofanon S, Schweitzer T, Krauss J, Rutkowski S, Debatin KM, Fulda S.
    Oncogene; 2011 May 12; 30(19):2275-81. PubMed ID: 21562496
    [Abstract] [Full Text] [Related]

  • 10. Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis.
    Opel D, Westhoff MA, Bender A, Braun V, Debatin KM, Fulda S.
    Cancer Res; 2008 Aug 01; 68(15):6271-80. PubMed ID: 18676851
    [Abstract] [Full Text] [Related]

  • 11. Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
    von Haefen C, Wieder T, Gillissen B, Stärck L, Graupner V, Dörken B, Daniel PT.
    Oncogene; 2002 Jun 06; 21(25):4009-19. PubMed ID: 12037683
    [Abstract] [Full Text] [Related]

  • 12. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
    Yamaguchi H, Bhalla K, Wang HG.
    Cancer Res; 2003 Apr 01; 63(7):1483-9. PubMed ID: 12670894
    [Abstract] [Full Text] [Related]

  • 13. Rituximab modifies the cisplatin-mitochondrial signaling pathway, resulting in apoptosis in cisplatin-resistant non-Hodgkin's lymphoma.
    Alas S, Ng CP, Bonavida B.
    Clin Cancer Res; 2002 Mar 01; 8(3):836-45. PubMed ID: 11895917
    [Abstract] [Full Text] [Related]

  • 14. Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells.
    Czaplinski S, Abhari BA, Torkov A, Seggewiß D, Hugle M, Fulda S.
    Oncotarget; 2015 Dec 08; 6(39):41522-34. PubMed ID: 26575016
    [Abstract] [Full Text] [Related]

  • 15. Ponicidin, an ent-kaurane diterpenoid derived from a constituent of the herbal supplement PC-SPES, Rabdosia rubescens, induces apoptosis by activation of caspase-3 and mitochondrial events in lung cancer cells in vitro.
    Liu JJ, Huang RW, Lin DJ, Peng J, Zhang M, Pan X, Hou M, Wu XY, Lin Q, Chen F.
    Cancer Invest; 2006 Mar 08; 24(2):136-48. PubMed ID: 16537182
    [Abstract] [Full Text] [Related]

  • 16. c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.
    Desbiens KM, Deschesnes RG, Labrie MM, Desfossés Y, Lambert H, Landry J, Bellmann K.
    Biochem J; 2003 Jun 01; 372(Pt 2):631-41. PubMed ID: 12646044
    [Abstract] [Full Text] [Related]

  • 17. Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis.
    Fulda S, Meyer E, Friesen C, Susin SA, Kroemer G, Debatin KM.
    Oncogene; 2001 Mar 01; 20(9):1063-75. PubMed ID: 11314043
    [Abstract] [Full Text] [Related]

  • 18. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 19. The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.
    Kang YH, Lee SJ.
    J Cell Physiol; 2008 Oct 22; 217(1):23-33. PubMed ID: 18412143
    [Abstract] [Full Text] [Related]

  • 20. Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells.
    Kurata K, Yanagisawa R, Ohira M, Kitagawa M, Nakagawara A, Kamijo T.
    Oncogene; 2008 Jan 31; 27(6):741-54. PubMed ID: 17653088
    [Abstract] [Full Text] [Related]


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