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Journal Abstract Search

115 related items for PubMed ID: 2085885

  • 1. Synthesis of human renin inhibitory peptides, angiotensinogen transition-state analogs containing a retro-inverso amide bond.
    Harada H, Iizuka K, Kamijo T, Akahane K, Yamamoto R, Nakano Y, Tsubaki A, Kubota T, Shimaoka I, Umeyama H.
    Chem Pharm Bull (Tokyo); 1990 Nov; 38(11):3042-7. PubMed ID: 2085885
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationships of human renin inhibitors designed from angiotensinogen transition state.
    Iizuka K, Kamijo T, Harada H, Akahane K, Kubota T, Etoh Y, Shimaoka I, Tsubaki A, Murakami M, Yamaguchi T.
    Chem Pharm Bull (Tokyo); 1990 Sep; 38(9):2487-93. PubMed ID: 2285979
    [Abstract] [Full Text] [Related]

  • 3. Orally potent human renin inhibitors derived from angiotensinogen transition state: design, synthesis, and mode of interaction.
    Iizuka K, Kamijo T, Harada H, Akahane K, Kubota T, Umeyama H, Ishida T, Kiso Y.
    J Med Chem; 1990 Oct; 33(10):2707-14. PubMed ID: 2120440
    [Abstract] [Full Text] [Related]

  • 4. Renin inhibitors containing psi[CH2O] pseudopeptide inserts.
    TenBrink RE, Pals DT, Harris DW, Johnson GA.
    J Med Chem; 1988 Mar; 31(3):671-7. PubMed ID: 3279210
    [Abstract] [Full Text] [Related]

  • 5. Design, structure-activity, and molecular modeling studies of potent renin inhibitory peptides having N-terminal Nin-For-Trp (Ftr): angiotensinogen congeners modified by P1-P1' Phe-Phe, Sta, Leu psi[CH(OH)CH2]Val or leu psi[CH2NH]Val substitutions.
    Sawyer TK, Pals DT, Mao B, Staples DJ, de Vaux AE, Maggiora LL, Affholter JA, Kati W, Duchamp D, Hester JB.
    J Med Chem; 1988 Jan; 31(1):18-30. PubMed ID: 3275777
    [Abstract] [Full Text] [Related]

  • 6. Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency.
    Luly JR, BaMaung N, Soderquist J, Fung AK, Stein H, Kleinert HD, Marcotte PA, Egan DA, Bopp B, Merits I.
    J Med Chem; 1988 Dec; 31(12):2264-76. PubMed ID: 3143009
    [Abstract] [Full Text] [Related]

  • 7. New human renin inhibitory peptides: angiotensinogen transition-state analogues containing novel Leu-Val replacement and a retro-inverso amide bond.
    Iizuka K, Kamijo T, Harada H, Akahane K, Kubota T, Shimaoka I, Umeyama H, Kiso Y.
    Chem Pharm Bull (Tokyo); 1988 Jun; 36(6):2278-81. PubMed ID: 3071424
    [No Abstract] [Full Text] [Related]

  • 8. Peptide analogues of angiotensinogen. Effect of peptide chain length on renin inhibition.
    Plattner JJ, Greer J, Fung AK, Stein H, Kleinert HD, Sham HL, Smital JR, Perun TJ.
    Biochem Biophys Res Commun; 1986 Sep 30; 139(3):982-90. PubMed ID: 3533075
    [Abstract] [Full Text] [Related]

  • 9. Exploiting the molecular template of angiotensinogen in the discovery and design of peptidyl, pseudopeptidyl and peptidimimetic inhibitors of human renin: a structure-activity perspective.
    Sawyer TK, Hester JB, Schostarez HJ, Thaisrivongs S, Bundy GL, Liu L, Bradford VS, De Vaux AE, Staples DJ, Maggiora LL.
    Adv Exp Med Biol; 1991 Sep 30; 306():307-23. PubMed ID: 1812721
    [No Abstract] [Full Text] [Related]

  • 10. Synthesis and renin inhibitory activity of angiotensinogen analogues having dehydrostatine, Leu psi [CH2S]Val, or Leu psi [CH2SO]Val at the P1-P1' cleavage site.
    Smith CW, Saneii HH, Sawyer TK, Pals DT, Scahill TA, Kamdar BV, Lawson JA.
    J Med Chem; 1988 Jul 30; 31(7):1377-82. PubMed ID: 3290486
    [Abstract] [Full Text] [Related]

  • 11. Renin inhibitors. I. Synthesis and structure-activity relationships of transition-state inhibitors containing homostatine analogues at the scissile bond.
    Atsuumi S, Nakano M, Koike Y, Tanaka S, Matsuyama K, Nakano M, Morishima H.
    Chem Pharm Bull (Tokyo); 1992 Feb 30; 40(2):364-70. PubMed ID: 1606632
    [Abstract] [Full Text] [Related]

  • 12. Conformationally constrained renin inhibitory peptides: cyclic (3-1)-1-(carboxymethyl)-L-prolyl-L-phenylalanyl-L-histidinamide as a conformational restriction at the P2-P4 tripeptide portion of the angiotensinogen template.
    Thaisrivongs S, Blinn JR, Pals DT, Turner SR.
    J Med Chem; 1991 Apr 30; 34(4):1276-82. PubMed ID: 2016704
    [Abstract] [Full Text] [Related]

  • 13. Renin inhibitors. Dipeptide analogues of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond.
    Bolis G, Fung AK, Greer J, Kleinert HD, Marcotte PA, Perun TJ, Plattner JJ, Stein HH.
    J Med Chem; 1987 Oct 30; 30(10):1729-37. PubMed ID: 3309313
    [Abstract] [Full Text] [Related]

  • 14. Potent in vivo inhibitors of rat renin: analogues of human and rat angiotensinogen sequences containing different classes of pseudodipeptides at the scissile site.
    Sueiras-Diaz J, Jones DM, Szelke M, Leckie BJ, Beattie SR, Beattie C, Morton JJ.
    J Pept Res; 1997 Oct 30; 50(4):239-47. PubMed ID: 9352462
    [Abstract] [Full Text] [Related]

  • 15. Renin inhibitors. Design and synthesis of a new class of conformationally restricted analogues of angiotensinogen.
    Sham HL, Bolis G, Stein HH, Fesik SW, Marcotte PA, Plattner JJ, Rempel CA, Greer J.
    J Med Chem; 1988 Feb 30; 31(2):284-95. PubMed ID: 3276890
    [Abstract] [Full Text] [Related]

  • 16. New inhibitors of human renin that contain novel Leu-Val replacements.
    Luly JR, Yi N, Soderquist J, Stein H, Cohen J, Perun TJ, Plattner JJ.
    J Med Chem; 1987 Sep 30; 30(9):1609-16. PubMed ID: 3305946
    [Abstract] [Full Text] [Related]

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  • 18. Conformational aspects of angiotensinogen analogues with renin inhibitory activity.
    Liepina I, Nikiforovich GV, Paiva AC.
    Biochem Biophys Res Commun; 1984 Jul 31; 122(2):700-5. PubMed ID: 6380499
    [Abstract] [Full Text] [Related]

  • 19. Novel renin inhibitors containing a non-peptide aminoalkanoyl moiety at P1-P1' position.
    Winiecka I, Marszałek D, Goldnik A, Jaworski P, Mazurek AP.
    Pharmazie; 2014 Apr 31; 69(4):263-70. PubMed ID: 24791589
    [Abstract] [Full Text] [Related]

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