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243 related items for PubMed ID: 20861008
1. Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin. Salameh MA, Soares AS, Navaneetham D, Sinha D, Walsh PN, Radisky ES. J Biol Chem; 2010 Nov 19; 285(47):36884-96. PubMed ID: 20861008 [Abstract] [Full Text] [Related]
2. Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin. Cohen I, Coban M, Shahar A, Sankaran B, Hockla A, Lacham S, Caulfield TR, Radisky ES, Papo N. J Biol Chem; 2019 Mar 29; 294(13):5105-5120. PubMed ID: 30700553 [Abstract] [Full Text] [Related]
3. Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin. Pendlebury D, Wang R, Henin RD, Hockla A, Soares AS, Madden BJ, Kazanov MD, Radisky ES. J Biol Chem; 2014 Nov 21; 289(47):32783-97. PubMed ID: 25301953 [Abstract] [Full Text] [Related]
4. Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Scheidig AJ, Hynes TR, Pelletier LA, Wells JA, Kossiakoff AA. Protein Sci; 1997 Sep 21; 6(9):1806-24. PubMed ID: 9300481 [Abstract] [Full Text] [Related]
5. Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. Alloy AP, Kayode O, Wang R, Hockla A, Soares AS, Radisky ES. J Biol Chem; 2015 Aug 28; 290(35):21523-35. PubMed ID: 26175157 [Abstract] [Full Text] [Related]
6. Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin. Salameh MA, Soares AS, Hockla A, Radisky ES. J Biol Chem; 2008 Feb 15; 283(7):4115-23. PubMed ID: 18077447 [Abstract] [Full Text] [Related]
7. Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors. Salameh MA, Soares AS, Alloy A, Radisky ES. Protein Sci; 2012 Aug 15; 21(8):1103-12. PubMed ID: 22610453 [Abstract] [Full Text] [Related]
8. The P(2)' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity. Salameh MA, Soares AS, Hockla A, Radisky DC, Radisky ES. Biochem J; 2011 Nov 15; 440(1):95-105. PubMed ID: 21806544 [Abstract] [Full Text] [Related]
19. Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. Zakharova E, Horvath MP, Goldenberg DP. J Mol Biol; 2008 Oct 17; 382(4):998-1013. PubMed ID: 18692070 [Abstract] [Full Text] [Related]
20. Substitutions at the P(1) position in BPTI strongly affect the association energy with serine proteinases. Grzesiak A, Helland R, Smalås AO, Krowarsch D, Dadlez M, Otlewski J. J Mol Biol; 2000 Aug 04; 301(1):205-17. PubMed ID: 10926503 [Abstract] [Full Text] [Related] Page: [Next] [New Search]