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276 related items for PubMed ID: 20862547
1. Blocking NF-κB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death. Bai L, Xu S, Chen W, Li Z, Wang X, Tang H, Lin Y. Apoptosis; 2011 Jan; 16(1):45-54. PubMed ID: 20862547 [Abstract] [Full Text] [Related]
2. IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells. Bai L, Chen W, Chen W, Wang X, Tang H, Lin Y. Mol Cancer Ther; 2009 Jun; 8(6):1636-45. PubMed ID: 19509265 [Abstract] [Full Text] [Related]
3. Attenuating Smac mimetic compound 3-induced NF-kappaB activation by luteolin leads to synergistic cytotoxicity in cancer cells. Bai L, Chen W, Wang X, Ju W, Xu S, Lin Y. J Cell Biochem; 2009 Dec 01; 108(5):1125-31. PubMed ID: 19739098 [Abstract] [Full Text] [Related]
4. Concurrent blockade of the NF-kappaB and Akt pathways potently sensitizes cancer cells to chemotherapeutic-induced cytotoxicity. He HN, Wang X, Zheng XL, Sun H, Shi XW, Zhong YJ, Huang B, Yang L, Li JK, Liao LC, Zhang L, Hu LN, Lin Y. Cancer Lett; 2010 Sep 01; 295(1):38-43. PubMed ID: 20207071 [Abstract] [Full Text] [Related]
5. Sensitization of TNF-induced cytotoxicity in lung cancer cells by concurrent suppression of the NF-kappaB and Akt pathways. Wang X, Chen W, Lin Y. Biochem Biophys Res Commun; 2007 Apr 13; 355(3):807-12. PubMed ID: 17316570 [Abstract] [Full Text] [Related]
6. Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo. Sun H, Zheng X, Wang Q, Yan J, Li D, Zhou Y, Lin Y, Zhang L, Wang X. Anticancer Drugs; 2012 Nov 13; 23(10):1039-46. PubMed ID: 22760211 [Abstract] [Full Text] [Related]
7. A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB. Dai Y, Liu M, Tang W, Li Y, Lian J, Lawrence TS, Xu L. BMC Cancer; 2009 Nov 06; 9():392. PubMed ID: 19895686 [Abstract] [Full Text] [Related]
8. 17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway. Wang X, Ju W, Renouard J, Aden J, Belinsky SA, Lin Y. Cancer Res; 2006 Jan 15; 66(2):1089-95. PubMed ID: 16424045 [Abstract] [Full Text] [Related]
9. Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression. Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao Q. Mol Cancer; 2011 Aug 31; 10():106. PubMed ID: 21880146 [Abstract] [Full Text] [Related]
10. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products. Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB. Cancer Res; 2005 Oct 15; 65(20):9555-65. PubMed ID: 16230421 [Abstract] [Full Text] [Related]
11. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death. Georgakis GV, Li Y, Rassidakis GZ, Martinez-Valdez H, Medeiros LJ, Younes A. Clin Cancer Res; 2006 Jan 15; 12(2):584-90. PubMed ID: 16428504 [Abstract] [Full Text] [Related]
12. HSP90 inhibition by 17-DMAG reduces inflammation in J774 macrophages through suppression of Akt and nuclear factor-κB pathways. Shimp SK, Parson CD, Regna NL, Thomas AN, Chafin CB, Reilly CM, Nichole Rylander M. Inflamm Res; 2012 May 15; 61(5):521-33. PubMed ID: 22327510 [Abstract] [Full Text] [Related]
13. Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway. Qu Z, Dong H, Xu X, Feng W, Yi X. Diagn Pathol; 2013 May 01; 8():70. PubMed ID: 23635099 [Abstract] [Full Text] [Related]
14. Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression. Petersen SL, Peyton M, Minna JD, Wang X. Proc Natl Acad Sci U S A; 2010 Jun 29; 107(26):11936-41. PubMed ID: 20547836 [Abstract] [Full Text] [Related]
15. Gambogic acid inhibits Hsp90 and deregulates TNF-α/NF-κB in HeLa cells. Zhang L, Yi Y, Chen J, Sun Y, Guo Q, Zheng Z, Song S. Biochem Biophys Res Commun; 2010 Dec 17; 403(3-4):282-7. PubMed ID: 21074517 [Abstract] [Full Text] [Related]
16. The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways. Wang R, Shao F, Liu Z, Zhang J, Wang S, Liu J, Liu H, Chen H, Liu K, Xia M, Wang Y. Chem Biol Interact; 2013 Sep 05; 205(1):1-10. PubMed ID: 23777986 [Abstract] [Full Text] [Related]
17. Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner. Wagner L, Marschall V, Karl S, Cristofanon S, Zobel K, Deshayes K, Vucic D, Debatin KM, Fulda S. Oncogene; 2013 Feb 21; 32(8):988-97. PubMed ID: 22469979 [Abstract] [Full Text] [Related]
18. Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation. Lewis J, Devin A, Miller A, Lin Y, Rodriguez Y, Neckers L, Liu ZG. J Biol Chem; 2000 Apr 07; 275(14):10519-26. PubMed ID: 10744744 [Abstract] [Full Text] [Related]
19. Synergistic cytotoxicity of BIIB021 with triptolide through suppression of PI3K/Akt/mTOR and NF-κB signal pathways in thyroid carcinoma cells. Kim SH, Kang JG, Kim CS, Ihm SH, Choi MG, Yoo HJ, Lee SJ. Biomed Pharmacother; 2016 Oct 07; 83():22-32. PubMed ID: 27470546 [Abstract] [Full Text] [Related]
20. Blocking of PI3K/AKT induces apoptosis by its effect on NF-κB activity in gastric carcinoma cell line SGC7901. Chao X, Zao J, Xiao-Yi G, Li-Jun M, Tao S. Biomed Pharmacother; 2010 Nov 07; 64(9):600-4. PubMed ID: 20947290 [Abstract] [Full Text] [Related] Page: [Next] [New Search]