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222 related items for PubMed ID: 20868758
1. Comparison of the NIDS® rapid assay with ELISA methods in immunogenicity testing of two biotherapeutics. Pan J, Small T, Qin D, Li S, Wang L, Chen D, Pauley C, Verch T, Kaplanski C, Bakhtiar R, Vallejo YR, Yin R. J Pharmacol Toxicol Methods; 2011; 63(2):150-9. PubMed ID: 20868758 [Abstract] [Full Text] [Related]
2. A double antigen bridging immunogenicity ELISA for the detection of antibodies to polyethylene glycol polymers. Liu Y, Reidler H, Pan J, Milunic D, Qin D, Chen D, Vallejo YR, Yin R. J Pharmacol Toxicol Methods; 2011; 64(3):238-45. PubMed ID: 21827863 [Abstract] [Full Text] [Related]
3. Subset analysis of patients experiencing clinical events of a potentially immunogenic nature in the pivotal clinical trials of tocilizumab for rheumatoid arthritis: Evaluation of an antidrug antibody ELISA using clinical adverse event-driven immunogenicity testing. Stubenrauch K, Wessels U, Birnboeck H, Ramirez F, Jahreis A, Schleypen J. Clin Ther; 2010 Aug; 32(9):1597-609. PubMed ID: 20974317 [Abstract] [Full Text] [Related]
4. Detection of low-affinity anti-drug antibodies and improved drug tolerance in immunogenicity testing by Octet(®) biolayer interferometry. Li J, Schantz A, Schwegler M, Shankar G. J Pharm Biomed Anal; 2011 Jan 25; 54(2):286-94. PubMed ID: 20869832 [Abstract] [Full Text] [Related]
5. Evaluation of a generic immunoassay with drug tolerance to detect immune complexes in serum samples from cynomolgus monkeys after administration of human antibodies. Stubenrauch K, Wessels U, Essig U, Vogel R, Schleypen J. J Pharm Biomed Anal; 2010 Jun 05; 52(2):249-54. PubMed ID: 20083366 [Abstract] [Full Text] [Related]
6. A novel homogeneous Biotin-digoxigenin based assay for the detection of human anti-therapeutic antibodies in autoimmune serum. Qiu ZJ, Ying Y, Fox M, Peng K, Lewin-Koh SC, Coleman D, Good J, Lowe J, Rahman A, Yang J, Jiang J, Quarmby V, Song A. J Immunol Methods; 2010 Oct 31; 362(1-2):101-11. PubMed ID: 20868690 [Abstract] [Full Text] [Related]
7. Solution ELISA as a platform of choice for development of robust, drug tolerant immunogenicity assays in support of drug development. Mikulskis A, Yeung D, Subramanyam M, Amaravadi L. J Immunol Methods; 2011 Feb 28; 365(1-2):38-49. PubMed ID: 21130095 [Abstract] [Full Text] [Related]
8. Attribution of the discrepancy between ELISA and LC-MS/MS assay results of a PEGylated scaffold protein in post-dose monkey plasma samples due to the presence of anti-drug antibodies. Wang SJ, Wu ST, Gokemeijer J, Fura A, Krishna M, Morin P, Chen G, Price K, Wang-Iverson D, Olah T, Weiner R, Tymiak A, Jemal M. Anal Bioanal Chem; 2012 Jan 28; 402(3):1229-39. PubMed ID: 22130720 [Abstract] [Full Text] [Related]
9. Epitope characterization of the ADA response directed against a targeted immunocytokine. Stubenrauch K, Künzel C, Vogel R, Tuerck D, Schick E, Heinrich J. J Pharm Biomed Anal; 2015 Oct 10; 114():296-304. PubMed ID: 26093509 [Abstract] [Full Text] [Related]
10. Generation of a Highly Specific Monoclonal Anti-Infliximab Antibody for Harmonization of TNF-Coated Infliximab Assays. Van Stappen T, Brouwers E, Tops S, Geukens N, Vermeire S, Declerck PJ, Gils A. Ther Drug Monit; 2015 Aug 10; 37(4):479-85. PubMed ID: 25525757 [Abstract] [Full Text] [Related]
11. Systematic comparison of drug-tolerant assays for anti-drug antibodies in a cohort of adalimumab-treated rheumatoid arthritis patients. Bloem K, van Leeuwen A, Verbeek G, Nurmohamed MT, Wolbink GJ, van der Kleij D, Rispens T. J Immunol Methods; 2015 Mar 10; 418():29-38. PubMed ID: 25637408 [Abstract] [Full Text] [Related]
12. Detection of antibodies against therapeutic proteins in the presence of residual therapeutic protein using a solid-phase extraction with acid dissociation (SPEAD) sample treatment prior to ELISA. Smith HW, Butterfield A, Sun D. Regul Toxicol Pharmacol; 2007 Dec 10; 49(3):230-7. PubMed ID: 17869396 [Abstract] [Full Text] [Related]
13. Development and validation of a homogeneous mobility shift assay for the measurement of infliximab and antibodies-to-infliximab levels in patient serum. Wang SL, Ohrmund L, Hauenstein S, Salbato J, Reddy R, Monk P, Lockton S, Ling N, Singh S. J Immunol Methods; 2012 Aug 31; 382(1-2):177-88. PubMed ID: 22691619 [Abstract] [Full Text] [Related]
14. In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug Development. Ubah OC, Porter AJ, Barelle CJ. J Immunol Res; 2020 Aug 31; 2020():7283239. PubMed ID: 32090129 [Abstract] [Full Text] [Related]
15. Strategies to estimate and improve drug tolerance in anti-drug antibody assays. Bütikofer L, Lemaillet G, Faust H. Bioanalysis; 2012 Aug 31; 4(16):1999-2012. PubMed ID: 22946916 [Abstract] [Full Text] [Related]
16. Conversion of a capture ELISA to a Luminex xMAP assay using a multiplex antibody screening method. Baker HN, Murphy R, Lopez E, Garcia C. J Vis Exp; 2012 Jul 06; (65):. PubMed ID: 22806215 [Abstract] [Full Text] [Related]
17. Improvement of drug tolerance in immunogenicity testing by acid treatment on Biacore. Sickert D, Kroeger K, Zickler C, Chokote E, Winkler B, Grenet JM, Legay F, Zaar A. J Immunol Methods; 2008 May 20; 334(1-2):29-36. PubMed ID: 18304570 [Abstract] [Full Text] [Related]
18. Application of a Plug-and-Play Immunogenicity Assay in Cynomolgus Monkey Serum for ADCs at Early Stages of Drug Development. Carrasco-Triguero M, Davis H, Zhu Y, Coleman D, Nazzal D, Vu P, Kaur S. J Immunol Res; 2016 May 20; 2016():2618575. PubMed ID: 27092313 [Abstract] [Full Text] [Related]
19. Recommendations for the characterization of immunogenicity response to multiple domain biotherapeutics. Gorovits B, Wakshull E, Pillutla R, Xu Y, Manning MS, Goyal J. J Immunol Methods; 2014 Jun 20; 408():1-12. PubMed ID: 24861938 [Abstract] [Full Text] [Related]
20. Development of a qualitative indirect ELISA for the measurement of rabies virus-specific antibodies from vaccinated dogs and cats. Cliquet F, McElhinney LM, Servat A, Boucher JM, Lowings JP, Goddard T, Mansfield KL, Fooks AR. J Virol Methods; 2004 Apr 20; 117(1):1-8. PubMed ID: 15019254 [Abstract] [Full Text] [Related] Page: [Next] [New Search]