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PUBMED FOR HANDHELDS

Journal Abstract Search


192 related items for PubMed ID: 20876384

  • 1. Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.
    Grunnet M, Abbruzzese J, Sachse FB, Sanguinetti MC.
    Mol Pharmacol; 2011 Jan; 79(1):1-9. PubMed ID: 20876384
    [Abstract] [Full Text] [Related]

  • 2. PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.
    Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC.
    Proc Natl Acad Sci U S A; 2009 Nov 24; 106(47):20075-80. PubMed ID: 19892732
    [Abstract] [Full Text] [Related]

  • 3. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.
    Perry M, Sachse FB, Sanguinetti MC.
    Proc Natl Acad Sci U S A; 2007 Aug 21; 104(34):13827-32. PubMed ID: 17693551
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  • 4. A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator.
    Perry M, Sanguinetti MC.
    Mol Pharmacol; 2008 Apr 21; 73(4):1044-51. PubMed ID: 18162604
    [Abstract] [Full Text] [Related]

  • 5. Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643.
    Durdagi S, Guo J, Lees-Miller JP, Noskov SY, Duff HJ.
    J Pharmacol Exp Ther; 2012 Aug 21; 342(2):441-52. PubMed ID: 22573844
    [Abstract] [Full Text] [Related]

  • 6. Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
    Hansen RS, Diness TG, Christ T, Demnitz J, Ravens U, Olesen SP, Grunnet M.
    Mol Pharmacol; 2006 Jan 21; 69(1):266-77. PubMed ID: 16219910
    [Abstract] [Full Text] [Related]

  • 7. C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.
    Gardner A, Sanguinetti MC.
    Mol Pharmacol; 2015 Jul 21; 88(1):19-28. PubMed ID: 25888115
    [Abstract] [Full Text] [Related]

  • 8. Mechanism of action of a novel human ether-a-go-go-related gene channel activator.
    Casis O, Olesen SP, Sanguinetti MC.
    Mol Pharmacol; 2006 Feb 21; 69(2):658-65. PubMed ID: 16284303
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  • 10. Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide.
    Garg V, Stary-Weinzinger A, Sachse F, Sanguinetti MC.
    Mol Pharmacol; 2011 Oct 21; 80(4):630-7. PubMed ID: 21743002
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  • 12. Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells.
    Schuster AM, Glassmeier G, Bauer CK.
    Mol Pharmacol; 2011 Nov 21; 80(5):930-42. PubMed ID: 21856740
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  • 14. Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea].
    Hansen RS, Diness TG, Christ T, Wettwer E, Ravens U, Olesen SP, Grunnet M.
    Mol Pharmacol; 2006 Oct 21; 70(4):1319-29. PubMed ID: 16825484
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  • 16. Kinetic model for NS1643 drug activation of WT and L529I variants of Kv11.1 (hERG1) potassium channel.
    Perissinotti LL, Guo J, De Biase PM, Clancy CE, Duff HJ, Noskov SY.
    Biophys J; 2015 Mar 24; 108(6):1414-1424. PubMed ID: 25809254
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