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192 related items for PubMed ID: 20876384
1. Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643. Grunnet M, Abbruzzese J, Sachse FB, Sanguinetti MC. Mol Pharmacol; 2011 Jan; 79(1):1-9. PubMed ID: 20876384 [Abstract] [Full Text] [Related]
2. PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance. Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC. Proc Natl Acad Sci U S A; 2009 Nov 24; 106(47):20075-80. PubMed ID: 19892732 [Abstract] [Full Text] [Related]
3. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. Perry M, Sachse FB, Sanguinetti MC. Proc Natl Acad Sci U S A; 2007 Aug 21; 104(34):13827-32. PubMed ID: 17693551 [Abstract] [Full Text] [Related]
4. A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator. Perry M, Sanguinetti MC. Mol Pharmacol; 2008 Apr 21; 73(4):1044-51. PubMed ID: 18162604 [Abstract] [Full Text] [Related]
5. Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643. Durdagi S, Guo J, Lees-Miller JP, Noskov SY, Duff HJ. J Pharmacol Exp Ther; 2012 Aug 21; 342(2):441-52. PubMed ID: 22573844 [Abstract] [Full Text] [Related]
6. Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643). Hansen RS, Diness TG, Christ T, Demnitz J, Ravens U, Olesen SP, Grunnet M. Mol Pharmacol; 2006 Jan 21; 69(1):266-77. PubMed ID: 16219910 [Abstract] [Full Text] [Related]
7. C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation. Gardner A, Sanguinetti MC. Mol Pharmacol; 2015 Jul 21; 88(1):19-28. PubMed ID: 25888115 [Abstract] [Full Text] [Related]
8. Mechanism of action of a novel human ether-a-go-go-related gene channel activator. Casis O, Olesen SP, Sanguinetti MC. Mol Pharmacol; 2006 Feb 21; 69(2):658-65. PubMed ID: 16284303 [Abstract] [Full Text] [Related]
14. Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea]. Hansen RS, Diness TG, Christ T, Wettwer E, Ravens U, Olesen SP, Grunnet M. Mol Pharmacol; 2006 Oct 21; 70(4):1319-29. PubMed ID: 16825484 [Abstract] [Full Text] [Related]