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Journal Abstract Search

248 related items for PubMed ID: 20885957

  • 1. Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim.
    Meng J, Fang B, Liao Y, Chresta CM, Smith PD, Roth JA.
    PLoS One; 2010 Sep 27; 5(9):e13026. PubMed ID: 20885957
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  • 2. The novel anti-MEK small molecule AZD6244 induces BIM-dependent and AKT-independent apoptosis in diffuse large B-cell lymphoma.
    Bhalla S, Evens AM, Dai B, Prachand S, Gordon LI, Gartenhaus RB.
    Blood; 2011 Jul 28; 118(4):1052-61. PubMed ID: 21628402
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  • 4. Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer.
    Yang JY, Chang CJ, Xia W, Wang Y, Wong KK, Engelman JA, Du Y, Andreeff M, Hortobagyi GN, Hung MC.
    Cancer Res; 2010 Jun 01; 70(11):4709-18. PubMed ID: 20484037
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  • 5. Dual inhibition of MEK1/2 and EGFR synergistically induces caspase-3-dependent apoptosis in EGFR inhibitor-resistant lung cancer cells via BIM upregulation.
    Song JY, Kim CS, Lee JH, Jang SJ, Lee SW, Hwang JJ, Lim C, Lee G, Seo J, Cho SY, Choi J.
    Invest New Drugs; 2013 Dec 01; 31(6):1458-65. PubMed ID: 24068620
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  • 8. 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells.
    Ding Q, Chen Y, Zhang Q, Guo Y, Huang Z, Dai L, Cao S.
    Mol Med Rep; 2015 Oct 01; 12(4):5100-8. PubMed ID: 26151347
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  • 10. Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.
    Stan SD, Hahm ER, Warin R, Singh SV.
    Cancer Res; 2008 Sep 15; 68(18):7661-9. PubMed ID: 18794155
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  • 11. Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.
    Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ.
    Sci Signal; 2011 Mar 29; 4(166):ra17. PubMed ID: 21447798
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  • 15. FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.
    Shukla S, Rizvi F, Raisuddin S, Kakkar P.
    Free Radic Biol Med; 2014 Nov 29; 76():185-99. PubMed ID: 25128467
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  • 17. FOXO3-mediated up-regulation of Bim contributes to rhein-induced cancer cell apoptosis.
    Wang J, Liu S, Yin Y, Li M, Wang B, Yang L, Jiang Y.
    Apoptosis; 2015 Mar 29; 20(3):399-409. PubMed ID: 25501496
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  • 18. Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells.
    Guan H, Song L, Cai J, Huang Y, Wu J, Yuan J, Li J, Li M.
    PLoS One; 2011 Mar 29; 6(5):e19946. PubMed ID: 21625639
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  • 19. MiR-92a mediates AZD6244 induced apoptosis and G1-phase arrest of lymphoma cells by targeting Bim.
    Lv XB, Zhang X, Deng L, Jiang L, Meng W, Lu Z, Wang X.
    Cell Biol Int; 2014 Apr 29; 38(4):435-43. PubMed ID: 24375836
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