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241 related items for PubMed ID: 20921230

  • 1. Direct and specific activation of human inward rectifier K+ channels by membrane phosphatidylinositol 4,5-bisphosphate.
    D'Avanzo N, Cheng WW, Doyle DA, Nichols CG.
    J Biol Chem; 2010 Nov 26; 285(48):37129-32. PubMed ID: 20921230
    [Abstract] [Full Text] [Related]

  • 2. Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2.
    Hansen SB, Tao X, MacKinnon R.
    Nature; 2011 Aug 28; 477(7365):495-8. PubMed ID: 21874019
    [Abstract] [Full Text] [Related]

  • 3. Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity.
    Xie LH, John SA, Ribalet B, Weiss JN.
    J Physiol; 2008 Apr 01; 586(7):1833-48. PubMed ID: 18276733
    [Abstract] [Full Text] [Related]

  • 4. Dual-mode phospholipid regulation of human inward rectifying potassium channels.
    Cheng WWL, D'Avanzo N, Doyle DA, Nichols CG.
    Biophys J; 2011 Feb 02; 100(3):620-628. PubMed ID: 21281576
    [Abstract] [Full Text] [Related]

  • 5. Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.
    Ponce-Balbuena D, López-Izquierdo A, Ferrer T, Rodríguez-Menchaca AA, Aréchiga-Figueroa IA, Sánchez-Chapula JA.
    J Pharmacol Exp Ther; 2009 Nov 02; 331(2):563-73. PubMed ID: 19654266
    [Abstract] [Full Text] [Related]

  • 6. In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).
    Hardie RC, Gu Y, Martin F, Sweeney ST, Raghu P.
    J Biol Chem; 2004 Nov 12; 279(46):47773-82. PubMed ID: 15355960
    [Abstract] [Full Text] [Related]

  • 7. Conformational changes at cytoplasmic intersubunit interactions control Kir channel gating.
    Wang S, Borschel WF, Heyman S, Hsu P, Nichols CG.
    J Biol Chem; 2017 Jun 16; 292(24):10087-10096. PubMed ID: 28446610
    [Abstract] [Full Text] [Related]

  • 8. Direct modulation of Kir channel gating by membrane phosphatidylinositol 4,5-bisphosphate.
    Enkvetchakul D, Jeliazkova I, Nichols CG.
    J Biol Chem; 2005 Oct 28; 280(43):35785-8. PubMed ID: 16144841
    [Abstract] [Full Text] [Related]

  • 9. Arachidonic acid activates Kir2.3 channels by enhancing channel-phosphatidyl-inositol 4,5-bisphosphate interactions.
    Wang C, Mirshahi UL, Liu B, Jia Z, Mirshahi T, Zhang H.
    Mol Pharmacol; 2008 Apr 28; 73(4):1185-94. PubMed ID: 18202303
    [Abstract] [Full Text] [Related]

  • 10. Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2).
    Ha J, Xu Y, Kawano T, Hendon T, Baki L, Garai S, Papapetropoulos A, Thakur GA, Plant LD, Logothetis DE.
    J Biol Chem; 2018 Mar 09; 293(10):3546-3561. PubMed ID: 29317494
    [Abstract] [Full Text] [Related]

  • 11. The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels.
    An HL, Lü SQ, Li JW, Meng XY, Zhan Y, Cui M, Long M, Zhang HL, Logothetis DE.
    J Biol Chem; 2012 Dec 07; 287(50):42278-87. PubMed ID: 23033482
    [Abstract] [Full Text] [Related]

  • 12. Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).
    Rosenhouse-Dantsker A, Noskov S, Han H, Adney SK, Tang QY, Rodríguez-Menchaca AA, Kowalsky GB, Petrou VI, Osborn CV, Logothetis DE, Levitan I.
    J Biol Chem; 2012 Nov 23; 287(48):40266-78. PubMed ID: 22995912
    [Abstract] [Full Text] [Related]

  • 13. Regulation of cardiac inwardly rectifying potassium channels by membrane lipid metabolism.
    Takano M, Kuratomi S.
    Prog Biophys Mol Biol; 2003 Jan 23; 81(1):67-79. PubMed ID: 12475570
    [Abstract] [Full Text] [Related]

  • 14. Lipids driving protein structure? Evolutionary adaptations in Kir channels.
    D'Avanzo N, Cheng WW, Wang S, Enkvetchakul D, Nichols CG.
    Channels (Austin); 2010 Jan 23; 4(3):139-41. PubMed ID: 21150302
    [Abstract] [Full Text] [Related]

  • 15. Energetics and location of phosphoinositide binding in human Kir2.1 channels.
    D'Avanzo N, Lee SJ, Cheng WWL, Nichols CG.
    J Biol Chem; 2013 Jun 07; 288(23):16726-16737. PubMed ID: 23564459
    [Abstract] [Full Text] [Related]

  • 16. Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.
    Schmidt MR, Stansfeld PJ, Tucker SJ, Sansom MS.
    Biochemistry; 2013 Jan 15; 52(2):279-81. PubMed ID: 23270460
    [Abstract] [Full Text] [Related]

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  • 20. Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators.
    Du X, Zhang H, Lopes C, Mirshahi T, Rohacs T, Logothetis DE.
    J Biol Chem; 2004 Sep 03; 279(36):37271-81. PubMed ID: 15155739
    [Abstract] [Full Text] [Related]

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