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283 related items for PubMed ID: 20940148
1. The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability. Durcan TM, Kontogiannea M, Thorarinsdottir T, Fallon L, Williams AJ, Djarmati A, Fantaneanu T, Paulson HL, Fon EA. Hum Mol Genet; 2011 Jan 01; 20(1):141-54. PubMed ID: 20940148 [Abstract] [Full Text] [Related]
2. Ataxin-3 and its e3 partners: implications for machado-joseph disease. Durcan TM, Fon EA. Front Neurol; 2013 Jan 01; 4():46. PubMed ID: 23653622 [Abstract] [Full Text] [Related]
3. [Polyglutamine-expanded ataxin-3 is degraded by autophagy]. Xiao H, Tang J, Hu Z, Tan J, Tang B, Jiang Z. Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2010 Feb 01; 27(1):23-8. PubMed ID: 20140862 [Abstract] [Full Text] [Related]
4. Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme. Durcan TM, Kontogiannea M, Bedard N, Wing SS, Fon EA. J Biol Chem; 2012 Jan 02; 287(1):531-541. PubMed ID: 22081612 [Abstract] [Full Text] [Related]
5. SUMO-1 modification on K166 of polyQ-expanded ataxin-3 strengthens its stability and increases its cytotoxicity. Zhou YF, Liao SS, Luo YY, Tang JG, Wang JL, Lei LF, Chi JW, Du J, Jiang H, Xia K, Tang BS, Shen L. PLoS One; 2013 Jan 02; 8(1):e54214. PubMed ID: 23382880 [Abstract] [Full Text] [Related]
6. Compromised mitochondrial complex II in models of Machado-Joseph disease. Laço MN, Oliveira CR, Paulson HL, Rego AC. Biochim Biophys Acta; 2012 Feb 02; 1822(2):139-49. PubMed ID: 22037589 [Abstract] [Full Text] [Related]
7. A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice. Colomer Gould VF, Goti D, Pearce D, Gonzalez GA, Gao H, Bermudez de Leon M, Jenkins NA, Copeland NG, Ross CA, Brown DR. Neurobiol Dis; 2007 Sep 02; 27(3):362-9. PubMed ID: 17632007 [Abstract] [Full Text] [Related]
8. Ataxin-3 protein modification as a treatment strategy for spinocerebellar ataxia type 3: removal of the CAG containing exon. Evers MM, Tran HD, Zalachoras I, Pepers BA, Meijer OC, den Dunnen JT, van Ommen GJ, Aartsma-Rus A, van Roon-Mom WM. Neurobiol Dis; 2013 Oct 02; 58():49-56. PubMed ID: 23659897 [Abstract] [Full Text] [Related]
9. In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis. Williams AJ, Knutson TM, Colomer Gould VF, Paulson HL. Neurobiol Dis; 2009 Mar 02; 33(3):342-53. PubMed ID: 19084066 [Abstract] [Full Text] [Related]
10. Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease. Matos CA, de Macedo-Ribeiro S, Carvalho AL. Prog Neurobiol; 2011 Sep 15; 95(1):26-48. PubMed ID: 21740957 [Abstract] [Full Text] [Related]
11. Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease. Nascimento-Ferreira I, Santos-Ferreira T, Sousa-Ferreira L, Auregan G, Onofre I, Alves S, Dufour N, Colomer Gould VF, Koeppen A, Déglon N, Pereira de Almeida L. Brain; 2011 May 15; 134(Pt 5):1400-15. PubMed ID: 21478185 [Abstract] [Full Text] [Related]
12. Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease. Alves S, Régulier E, Nascimento-Ferreira I, Hassig R, Dufour N, Koeppen A, Carvalho AL, Simões S, de Lima MC, Brouillet E, Gould VC, Déglon N, de Almeida LP. Hum Mol Genet; 2008 Jul 15; 17(14):2071-83. PubMed ID: 18385100 [Abstract] [Full Text] [Related]
14. Mutant ataxin-3 promotes the autophagic degradation of parkin. Durcan TM, Fon EA. Autophagy; 2011 Feb 15; 7(2):233-4. PubMed ID: 21116127 [Abstract] [Full Text] [Related]
15. Toward therapeutic targets for SCA3: Insight into the role of Machado-Joseph disease protein ataxin-3 in misfolded proteins clearance. Li X, Liu H, Fischhaber PL, Tang TS. Prog Neurobiol; 2015 Sep 15; 132():34-58. PubMed ID: 26123252 [Abstract] [Full Text] [Related]
16. Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice. Nóbrega C, Nascimento-Ferreira I, Onofre I, Albuquerque D, Hirai H, Déglon N, de Almeida LP. PLoS One; 2013 Sep 15; 8(1):e52396. PubMed ID: 23349684 [Abstract] [Full Text] [Related]
17. KPNB1 modulates the Machado-Joseph disease protein ataxin-3 through activation of the mitochondrial protease CLPP. Abeditashi M, Weber JJ, Pereira Sena P, Velic A, Kalimeri M, Incebacak Eltemur RD, Schmidt J, Hübener-Schmid J, Hauser S, Macek B, Riess O, Schmidt T. Cell Mol Life Sci; 2022 Jul 06; 79(8):401. PubMed ID: 35794401 [Abstract] [Full Text] [Related]
18. A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration. Goti D, Katzen SM, Mez J, Kurtis N, Kiluk J, Ben-Haïem L, Jenkins NA, Copeland NG, Kakizuka A, Sharp AH, Ross CA, Mouton PR, Colomer V. J Neurosci; 2004 Nov 10; 24(45):10266-79. PubMed ID: 15537899 [Abstract] [Full Text] [Related]
19. Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease. Nascimento-Ferreira I, Nóbrega C, Vasconcelos-Ferreira A, Onofre I, Albuquerque D, Aveleira C, Hirai H, Déglon N, Pereira de Almeida L. Brain; 2013 Jul 10; 136(Pt 7):2173-88. PubMed ID: 23801739 [Abstract] [Full Text] [Related]
20. Motor uncoordination and neuropathology in a transgenic mouse model of Machado-Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products. Silva-Fernandes A, Costa Mdo C, Duarte-Silva S, Oliveira P, Botelho CM, Martins L, Mariz JA, Ferreira T, Ribeiro F, Correia-Neves M, Costa C, Maciel P. Neurobiol Dis; 2010 Oct 10; 40(1):163-76. PubMed ID: 20510362 [Abstract] [Full Text] [Related] Page: [Next] [New Search]