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Journal Abstract Search

309 related items for PubMed ID: 20952194

  • 1. C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: anticancer profile and G-quadruplex stabilization.
    Lavrado J, Reszka AP, Moreira R, Neidle S, Paulo A.
    Bioorg Med Chem Lett; 2010 Dec 01; 20(23):7042-5. PubMed ID: 20952194
    [Abstract] [Full Text] [Related]

  • 2. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
    Sparapani S, Haider SM, Doria F, Gunaratnam M, Neidle S.
    J Am Chem Soc; 2010 Sep 08; 132(35):12263-72. PubMed ID: 20718414
    [Abstract] [Full Text] [Related]

  • 3. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
    Collie GW, Promontorio R, Hampel SM, Micco M, Neidle S, Parkinson GN.
    J Am Chem Soc; 2012 Feb 08; 134(5):2723-31. PubMed ID: 22280460
    [Abstract] [Full Text] [Related]

  • 4. 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
    Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ.
    J Med Chem; 2008 Oct 23; 51(20):6381-92. PubMed ID: 18821749
    [Abstract] [Full Text] [Related]

  • 5. Cryptolepine and aromathecin based mimics as potent G-quadruplex-binding, DNA-cleavage and anticancer agents: Design, synthesis and DNA targeting-induced apoptosis.
    Yuan JM, Wei K, Zhang GH, Chen NY, Wei XW, Pan CX, Mo DL, Su GF.
    Eur J Med Chem; 2019 May 01; 169():144-158. PubMed ID: 30875505
    [Abstract] [Full Text] [Related]

  • 6. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
    Moore MJ, Schultes CM, Cuesta J, Cuenca F, Gunaratnam M, Tanious FA, Wilson WD, Neidle S.
    J Med Chem; 2006 Jan 26; 49(2):582-99. PubMed ID: 16420044
    [Abstract] [Full Text] [Related]

  • 7. Selective G-quadruplex ligands: the significant role of side chain charge density in a series of perylene derivatives.
    Micheli E, Lombardo CM, D'Ambrosio D, Franceschin M, Neidle S, Savino M.
    Bioorg Med Chem Lett; 2009 Jul 15; 19(14):3903-8. PubMed ID: 19376705
    [Abstract] [Full Text] [Related]

  • 8. Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer.
    Chan DS, Yang H, Kwan MH, Cheng Z, Lee P, Bai LP, Jiang ZH, Wong CY, Fong WF, Leung CH, Ma DL.
    Biochimie; 2011 Jun 15; 93(6):1055-64. PubMed ID: 21377506
    [Abstract] [Full Text] [Related]

  • 9. Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence.
    Di Leva FS, Zizza P, Cingolani C, D'Angelo C, Pagano B, Amato J, Salvati E, Sissi C, Pinato O, Marinelli L, Cavalli A, Cosconati S, Novellino E, Randazzo A, Biroccio A.
    J Med Chem; 2013 Dec 12; 56(23):9646-54. PubMed ID: 24256368
    [Abstract] [Full Text] [Related]

  • 10. Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.
    Ou TM, Lu YJ, Zhang C, Huang ZS, Wang XD, Tan JH, Chen Y, Ma DL, Wong KY, Tang JC, Chan AS, Gu LQ.
    J Med Chem; 2007 Apr 05; 50(7):1465-74. PubMed ID: 17346034
    [Abstract] [Full Text] [Related]

  • 11. Homogeneous selecting of a quadruplex-binding ligand-based gold nanoparticle fluorescence resonance energy transfer assay.
    Jin Y, Li H, Bai J.
    Anal Chem; 2009 Jul 15; 81(14):5709-15. PubMed ID: 19527045
    [Abstract] [Full Text] [Related]

  • 12. Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Wu WB, Chen SH, Hou JQ, Tan JH, Ou TM, Huang SL, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2011 Apr 21; 9(8):2975-86. PubMed ID: 21373680
    [Abstract] [Full Text] [Related]

  • 13. Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition.
    Chen Z, Zheng KW, Hao YH, Tan Z.
    J Am Chem Soc; 2009 Aug 05; 131(30):10430-8. PubMed ID: 19588966
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, G-quadruplex stabilisation, docking studies, and effect on cancer cells of indolo[3,2-b]quinolines with one, two, or three basic side chains.
    Lavrado J, Borralho PM, Ohnmacht SA, Castro RE, Rodrigues CM, Moreira R, dos Santos DJ, Neidle S, Paulo A.
    ChemMedChem; 2013 Oct 05; 8(10):1648-61. PubMed ID: 23960016
    [Abstract] [Full Text] [Related]

  • 15. Incorporation of basic side chains into cryptolepine scaffold: structure-antimalarial activity relationships and mechanistic studies.
    Lavrado J, Cabal GG, Prudêncio M, Mota MM, Gut J, Rosenthal PJ, Díaz C, Guedes RC, dos Santos DJ, Bichenkova E, Douglas KT, Moreira R, Paulo A.
    J Med Chem; 2011 Feb 10; 54(3):734-50. PubMed ID: 21207937
    [Abstract] [Full Text] [Related]

  • 16. Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
    Musumeci D, Amato J, Zizza P, Platella C, Cosconati S, Cingolani C, Biroccio A, Novellino E, Randazzo A, Giancola C, Pagano B, Montesarchio D.
    Biochim Biophys Acta Gen Subj; 2017 May 10; 1861(5 Pt B):1341-1352. PubMed ID: 28130159
    [Abstract] [Full Text] [Related]

  • 17. Benzofuroquinoline derivatives had remarkable improvement of their selectivity for telomeric G-quadruplex DNA over duplex DNA upon introduction of peptidyl group.
    Long Y, Li Z, Tan JH, Ou TM, Li D, Gu LQ, Huang ZS.
    Bioconjug Chem; 2012 Sep 19; 23(9):1821-31. PubMed ID: 22871222
    [Abstract] [Full Text] [Related]

  • 18. Stable anticancer gold(III)-porphyrin complexes: effects of porphyrin structure.
    Sun RW, Li CK, Ma DL, Yan JJ, Lok CN, Leung CH, Zhu N, Che CM.
    Chemistry; 2010 Mar 08; 16(10):3097-113. PubMed ID: 20162647
    [Abstract] [Full Text] [Related]

  • 19. Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA.
    Peng D, Tan JH, Chen SB, Ou TM, Gu LQ, Huang ZS.
    Bioorg Med Chem; 2010 Dec 01; 18(23):8235-42. PubMed ID: 21036049
    [Abstract] [Full Text] [Related]

  • 20. DNA loop sequence as the determinant for chiral supramolecular compound G-quadruplex selectivity.
    Yu H, Zhao C, Chen Y, Fu M, Ren J, Qu X.
    J Med Chem; 2010 Jan 14; 53(1):492-8. PubMed ID: 19911822
    [Abstract] [Full Text] [Related]

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