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341 related items for PubMed ID: 20959361

  • 1. Curcumin dually inhibits both mammalian target of rapamycin and nuclear factor-κB pathways through a crossed phosphatidylinositol 3-kinase/Akt/IκB kinase complex signaling axis in adenoid cystic carcinoma.
    Sun ZJ, Chen G, Zhang W, Hu X, Liu Y, Zhou Q, Zhu LX, Zhao YF.
    Mol Pharmacol; 2011 Jan; 79(1):106-18. PubMed ID: 20959361
    [Abstract] [Full Text] [Related]

  • 2. Activation of PI3K/Akt/IKK-alpha/NF-kappaB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin.
    Sun ZJ, Chen G, Hu X, Zhang W, Liu Y, Zhu LX, Zhou Q, Zhao YF.
    Apoptosis; 2010 Jul; 15(7):850-63. PubMed ID: 20386985
    [Abstract] [Full Text] [Related]

  • 3. Mammalian target of rapamycin pathway promotes tumor-induced angiogenesis in adenoid cystic carcinoma: its suppression by isoliquiritigenin through dual activation of c-Jun NH2-terminal kinase and inhibition of extracellular signal-regulated kinase.
    Sun ZJ, Chen G, Zhang W, Hu X, Huang CF, Wang YF, Jia J, Zhao YF.
    J Pharmacol Exp Ther; 2010 Aug; 334(2):500-12. PubMed ID: 20484154
    [Abstract] [Full Text] [Related]

  • 4. Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IκB kinase activity.
    Singhal E, Sen P.
    Int J Biochem Cell Biol; 2011 Aug; 43(8):1134-46. PubMed ID: 21536148
    [Abstract] [Full Text] [Related]

  • 5. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.
    Mol Pharmacol; 2006 Jan; 69(1):195-206. PubMed ID: 16219905
    [Abstract] [Full Text] [Related]

  • 6. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.
    Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE, Price JE.
    Clin Cancer Res; 2005 Oct 15; 11(20):7490-8. PubMed ID: 16243823
    [Abstract] [Full Text] [Related]

  • 7. 2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.
    Li CM, Narayanan R, Lu Y, Hurh E, Coss CC, Barrett CM, Miller DD, Dalton JT.
    Int J Oncol; 2010 Oct 15; 37(4):1023-30. PubMed ID: 20811725
    [Abstract] [Full Text] [Related]

  • 8. Liposome-encapsulated curcumin suppresses growth of head and neck squamous cell carcinoma in vitro and in xenografts through the inhibition of nuclear factor kappaB by an AKT-independent pathway.
    Wang D, Veena MS, Stevenson K, Tang C, Ho B, Suh JD, Duarte VM, Faull KF, Mehta K, Srivatsan ES, Wang MB.
    Clin Cancer Res; 2008 Oct 01; 14(19):6228-36. PubMed ID: 18829502
    [Abstract] [Full Text] [Related]

  • 9. Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma.
    Clark CA, McEachern MD, Shah SH, Rong Y, Rong X, Smelley CL, Caldito GC, Abreo FW, Nathan CO.
    Cancer Prev Res (Phila); 2010 Dec 01; 3(12):1586-95. PubMed ID: 20851953
    [Abstract] [Full Text] [Related]

  • 10. Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products.
    Kunnumakkara AB, Diagaradjane P, Guha S, Deorukhkar A, Shentu S, Aggarwal BB, Krishnan S.
    Clin Cancer Res; 2008 Apr 01; 14(7):2128-36. PubMed ID: 18381954
    [Abstract] [Full Text] [Related]

  • 11. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways.
    Aoki H, Takada Y, Kondo S, Sawaya R, Aggarwal BB, Kondo Y.
    Mol Pharmacol; 2007 Jul 01; 72(1):29-39. PubMed ID: 17395690
    [Abstract] [Full Text] [Related]

  • 12. Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2-mediated PI3K/Akt/mTOR signaling pathway.
    He L, Wu Y, Lin L, Wang J, Wu Y, Chen Y, Yi Z, Liu M, Pang X.
    Cancer Sci; 2011 Jan 01; 102(1):219-25. PubMed ID: 21087351
    [Abstract] [Full Text] [Related]

  • 13. Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer.
    Sreekanth CN, Bava SV, Sreekumar E, Anto RJ.
    Oncogene; 2011 Jul 14; 30(28):3139-52. PubMed ID: 21317920
    [Abstract] [Full Text] [Related]

  • 14. HS-116, a novel phosphatidylinositol 3-kinase inhibitor induces apoptosis and suppresses angiogenesis of hepatocellular carcinoma through inhibition of the PI3K/AKT/mTOR pathway.
    Jung KH, Choi MJ, Hong S, Lee H, Hong SW, Zheng HM, Lee HS, Hong S, Hong SS.
    Cancer Lett; 2012 Mar 28; 316(2):187-95. PubMed ID: 22182943
    [Abstract] [Full Text] [Related]

  • 15. Down-regulation of the nuclear factor-kappaB by lidamycin in association with inducing apoptosis in human pancreatic cancer cells and inhibiting xenograft growth.
    Chen J, Ouyang ZG, Zhang SH, Zhen YS.
    Oncol Rep; 2007 Jun 28; 17(6):1445-51. PubMed ID: 17487403
    [Abstract] [Full Text] [Related]

  • 16. Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway.
    Choi BH, Kim CG, Lim Y, Shin SY, Lee YH.
    Cancer Lett; 2008 Jan 18; 259(1):111-8. PubMed ID: 18006147
    [Abstract] [Full Text] [Related]

  • 17. Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism.
    Bava SV, Sreekanth CN, Thulasidasan AK, Anto NP, Cheriyan VT, Puliyappadamba VT, Menon SG, Ravichandran SD, Anto RJ.
    Int J Biochem Cell Biol; 2011 Mar 18; 43(3):331-41. PubMed ID: 20883815
    [Abstract] [Full Text] [Related]

  • 18. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.
    Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS.
    Cancer Res; 2005 Nov 01; 65(21):9953-61. PubMed ID: 16267020
    [Abstract] [Full Text] [Related]

  • 19. Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.
    Sun H, Zheng X, Wang Q, Yan J, Li D, Zhou Y, Lin Y, Zhang L, Wang X.
    Anticancer Drugs; 2012 Nov 01; 23(10):1039-46. PubMed ID: 22760211
    [Abstract] [Full Text] [Related]

  • 20. Kalopanaxsaponin A inhibits PMA-induced invasion by reducing matrix metalloproteinase-9 via PI3K/Akt- and PKCdelta-mediated signaling in MCF-7 human breast cancer cells.
    Park SK, Hwang YS, Park KK, Park HJ, Seo JY, Chung WY.
    Carcinogenesis; 2009 Jul 01; 30(7):1225-33. PubMed ID: 19420016
    [Abstract] [Full Text] [Related]


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