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204 related items for PubMed ID: 20959464

  • 1. Altered chaperone-like activity of alpha-crystallins promotes cataractogenesis.
    Cheng C, Xia CH, Huang Q, Ding L, Horwitz J, Gong X.
    J Biol Chem; 2010 Dec 24; 285(52):41187-93. PubMed ID: 20959464
    [Abstract] [Full Text] [Related]

  • 2. AlphaA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice.
    Andley UP.
    BMC Ophthalmol; 2009 Jul 20; 9():4. PubMed ID: 19619312
    [Abstract] [Full Text] [Related]

  • 3. In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin.
    Andley UP, Malone JP, Townsend RR.
    PLoS One; 2014 Jul 20; 9(4):e95507. PubMed ID: 24760011
    [Abstract] [Full Text] [Related]

  • 4. Crystallin {gamma}B-I4F mutant protein binds to {alpha}-crystallin and affects lens transparency.
    Liu H, Du X, Wang M, Huang Q, Ding L, McDonald HW, Yates JR, Beutler B, Horwitz J, Gong X.
    J Biol Chem; 2005 Jul 01; 280(26):25071-8. PubMed ID: 15878859
    [Abstract] [Full Text] [Related]

  • 5. Mechanism of cataract formation in alphaA-crystallin Y118D mutation.
    Huang Q, Ding L, Phan KB, Cheng C, Xia CH, Gong X, Horwitz J.
    Invest Ophthalmol Vis Sci; 2009 Jun 01; 50(6):2919-26. PubMed ID: 19151380
    [Abstract] [Full Text] [Related]

  • 6. Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency.
    Xia CH, Liu H, Chang B, Cheng C, Cheung D, Wang M, Huang Q, Horwitz J, Gong X.
    Invest Ophthalmol Vis Sci; 2006 Jul 01; 47(7):3004-10. PubMed ID: 16799046
    [Abstract] [Full Text] [Related]

  • 7. Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death.
    Xi JH, Bai F, Gross J, Townsend RR, Menko AS, Andley UP.
    J Biol Chem; 2008 Feb 29; 283(9):5801-14. PubMed ID: 18056999
    [Abstract] [Full Text] [Related]

  • 8. In vivo lens deficiency of the R49C alphaA-crystallin mutant.
    Andley UP, Reilly MA.
    Exp Eye Res; 2010 Jun 29; 90(6):699-702. PubMed ID: 20188090
    [Abstract] [Full Text] [Related]

  • 9. Autophagy and UPR in alpha-crystallin mutant knock-in mouse models of hereditary cataracts.
    Andley UP, Goldman JW.
    Biochim Biophys Acta; 2016 Jan 29; 1860(1 Pt B):234-9. PubMed ID: 26071686
    [Abstract] [Full Text] [Related]

  • 10. Cataract mutation P20S of alphaB-crystallin impairs chaperone activity of alphaA-crystallin and induces apoptosis of human lens epithelial cells.
    Li H, Li C, Lu Q, Su T, Ke T, Li DW, Yuan M, Liu J, Ren X, Zhang Z, Zeng S, Wang QK, Liu M.
    Biochim Biophys Acta; 2008 May 29; 1782(5):303-9. PubMed ID: 18343237
    [Abstract] [Full Text] [Related]

  • 11. Probing the changes in gene expression due to α-crystallin mutations in mouse models of hereditary human cataract.
    Andley UP, Tycksen E, McGlasson-Naumann BN, Hamilton PD.
    PLoS One; 2018 May 29; 13(1):e0190817. PubMed ID: 29338044
    [Abstract] [Full Text] [Related]

  • 12. Loss of αBa-crystallin, but not αA-crystallin, increases age-related cataract in the zebrafish lens.
    Posner M, Garver T, Kaye T, Brdicka S, Suttle M, Patterson B, Farnsworth DR.
    Exp Eye Res; 2024 Jul 29; 244():109918. PubMed ID: 38705506
    [Abstract] [Full Text] [Related]

  • 13. The IXI/V motif in the C-terminal extension of alpha-crystallins: alternative interactions and oligomeric assemblies.
    Pasta SY, Raman B, Ramakrishna T, Rao ChM.
    Mol Vis; 2004 Sep 08; 10():655-62. PubMed ID: 15448619
    [Abstract] [Full Text] [Related]

  • 14. Synergistic effects of metal ion and the pre-senile cataract-causing G98R alphaA-crystallin: self-aggregation propensities and chaperone activity.
    Singh D, Tangirala R, Bakthisaran R, Chintalagiri MR.
    Mol Vis; 2009 Oct 16; 15():2050-60. PubMed ID: 19862354
    [Abstract] [Full Text] [Related]

  • 15. Effects of alpha-crystallin on lens cell function and cataract pathology.
    Andley UP.
    Curr Mol Med; 2009 Sep 16; 9(7):887-92. PubMed ID: 19860667
    [Abstract] [Full Text] [Related]

  • 16. Lens proteome map and alpha-crystallin profile of the catfish Rita rita.
    Mohanty BP, Bhattacharjee S, Das MK.
    Indian J Biochem Biophys; 2011 Feb 16; 48(1):35-41. PubMed ID: 21469600
    [Abstract] [Full Text] [Related]

  • 17. Zebrafish alpha-crystallins: protein structure and chaperone-like activity compared to their mammalian orthologs.
    Dahlman JM, Margot KL, Ding L, Horwitz J, Posner M.
    Mol Vis; 2005 Jan 26; 11():88-96. PubMed ID: 15692462
    [Abstract] [Full Text] [Related]

  • 18. Negative charge at aspartate 151 is important for human lens αA-crystallin stability and chaperone function.
    Takata T, Matsubara T, Nakamura-Hirota T, Fujii N.
    Exp Eye Res; 2019 May 26; 182():10-18. PubMed ID: 30849387
    [Abstract] [Full Text] [Related]

  • 19. Expression of Cataract-linked γ-Crystallin Variants in Zebrafish Reveals a Proteostasis Network That Senses Protein Stability.
    Wu SY, Zou P, Fuller AW, Mishra S, Wang Z, Schey KL, Mchaourab HS.
    J Biol Chem; 2016 Dec 02; 291(49):25387-25397. PubMed ID: 27770023
    [Abstract] [Full Text] [Related]

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