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Journal Abstract Search

311 related items for PubMed ID: 20962062

  • 1. Quantitative investigation of the impact of P-glycoprotein inhibition on drug transport across blood-brain barrier in rats.
    Sugimoto H, Hirabayashi H, Kimura Y, Furuta A, Amano N, Moriwaki T.
    Drug Metab Dispos; 2011 Jan; 39(1):8-14. PubMed ID: 20962062
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  • 2. In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier.
    Hsiao P, Bui T, Ho RJ, Unadkat JD.
    Drug Metab Dispos; 2008 Mar; 36(3):481-4. PubMed ID: 18057117
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  • 3. A simplified protocol employing elacridar in rodents: a screening model in drug discovery to assess P-gp mediated efflux at the blood brain barrier.
    Kallem R, Kulkarni CP, Patel D, Thakur M, Sinz M, Singh SP, Mahammad SS, Mandlekar S.
    Drug Metab Lett; 2012 Jun 01; 6(2):134-44. PubMed ID: 23061481
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  • 4. Verapamil P-glycoprotein transport across the rat blood-brain barrier: cyclosporine, a concentration inhibition analysis, and comparison with human data.
    Hsiao P, Sasongko L, Link JM, Mankoff DA, Muzi M, Collier AC, Unadkat JD.
    J Pharmacol Exp Ther; 2006 May 01; 317(2):704-10. PubMed ID: 16415090
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  • 7. Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies.
    Batrakova EV, Miller DW, Li S, Alakhov VY, Kabanov AV, Elmquist WF.
    J Pharmacol Exp Ther; 2001 Feb 01; 296(2):551-7. PubMed ID: 11160643
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  • 9. Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys.
    Uchida Y, Wakayama K, Ohtsuki S, Chiba M, Ohe T, Ishii Y, Terasaki T.
    J Pharmacol Exp Ther; 2014 Sep 01; 350(3):578-88. PubMed ID: 24947467
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  • 10. Effect of P-glycoprotein-mediated efflux on cerebrospinal fluid/plasma concentration ratio.
    Ohe T, Sato M, Tanaka S, Fujino N, Hata M, Shibata Y, Kanatani A, Fukami T, Yamazaki M, Chiba M, Ishii Y.
    Drug Metab Dispos; 2003 Oct 01; 31(10):1251-4. PubMed ID: 12975334
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  • 13. Comparison of drug efflux transport kinetics in various blood-brain barrier models.
    Bachmeier CJ, Trickler WJ, Miller DW.
    Drug Metab Dispos; 2006 Jun 01; 34(6):998-1003. PubMed ID: 16554372
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  • 14. Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro.
    Wandel C, Kim RB, Guengerich FP, Wood AJ.
    Drug Metab Dispos; 2000 Aug 01; 28(8):895-8. PubMed ID: 10901697
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  • 15. In vitro to in vivo comparison of the substrate characteristics of sorafenib tosylate toward P-glycoprotein.
    Gnoth MJ, Sandmann S, Engel K, Radtke M.
    Drug Metab Dispos; 2010 Aug 01; 38(8):1341-6. PubMed ID: 20413726
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  • 17. Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug.
    Fenner KS, Troutman MD, Kempshall S, Cook JA, Ware JA, Smith DA, Lee CA.
    Clin Pharmacol Ther; 2009 Feb 01; 85(2):173-81. PubMed ID: 18987624
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  • 18. Influence of time to achieve substrate distribution equilibrium between brain tissue and blood on quantitation of the blood-brain barrier P-glycoprotein effect.
    Padowski JM, Pollack GM.
    Brain Res; 2011 Dec 02; 1426():1-17. PubMed ID: 22036081
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  • 19. In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein.
    Liang Y, Zhou Y, Zhang J, Liu Y, Guan T, Wang Y, Xing L, Rao T, Zhou L, Hao K, Xie L, Wang GJ.
    Phytomedicine; 2013 Aug 15; 20(11):1030-8. PubMed ID: 23731657
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  • 20. In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity.
    Madlova M, Bosquillon C, Asker D, Dolezal P, Forbes B.
    J Pharm Pharmacol; 2009 Mar 15; 61(3):293-301. PubMed ID: 19222901
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