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Journal Abstract Search


165 related items for PubMed ID: 20970346

  • 1. Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of a six-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative.
    Mohan S, Sim L, Rose DR, Pinto BM.
    Bioorg Med Chem; 2010 Nov 15; 18(22):7794-8. PubMed ID: 20970346
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  • 5. New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
    Sim L, Jayakanthan K, Mohan S, Nasi R, Johnston BD, Pinto BM, Rose DR.
    Biochemistry; 2010 Jan 26; 49(3):443-51. PubMed ID: 20039683
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  • 6. Structure proof and synthesis of kotalanol and de-O-sulfonated kotalanol, glycosidase inhibitors isolated from an herbal remedy for the treatment of type-2 diabetes.
    Jayakanthan K, Mohan S, Pinto BM.
    J Am Chem Soc; 2009 Apr 22; 131(15):5621-6. PubMed ID: 19331410
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  • 9. Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives.
    Rossi EJ, Sim L, Kuntz DA, Hahn D, Johnston BD, Ghavami A, Szczepina MG, Kumar NS, Sterchi EE, Nichols BL, Pinto BM, Rose DR.
    FEBS J; 2006 Jun 22; 273(12):2673-83. PubMed ID: 16817895
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  • 12. Probing the active-site requirements of human intestinal N-terminal maltase glucoamylase: the effect of replacing the sulfate moiety by a methyl ether in ponkoranol, a naturally occurring α-glucosidase inhibitor.
    Eskandari R, Jones K, Rose DR, Pinto BM.
    Bioorg Med Chem Lett; 2010 Oct 01; 20(19):5686-9. PubMed ID: 20801033
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  • 17. Potent glucosidase inhibitors: de-O-sulfonated ponkoranol and its stereoisomer.
    Eskandari R, Kuntz DA, Rose DR, Pinto BM.
    Org Lett; 2010 Apr 02; 12(7):1632-5. PubMed ID: 20218632
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  • 18. A new class of glucosidase inhibitor: analogues of the naturally occurring glucosidase inhibitor salacinol with different ring heteroatom substituents and acyclic chain extension.
    Liu H, Sim L, Rose DR, Pinto BM.
    J Org Chem; 2006 Apr 14; 71(8):3007-13. PubMed ID: 16599595
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  • 19. Synthesis of a salacinol analogue and its alpha-glucosidase inhibitory activity.
    Shao Y, Osamu M, Kazuya Y, Yoshiharu M, Eriko Y, Toshie M, Genzoh T, Hisashi M, Masayuki Y, You QD.
    Yao Xue Xue Bao; 2006 Jul 14; 41(7):647-53. PubMed ID: 17007358
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  • 20. Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity.
    Sim L, Quezada-Calvillo R, Sterchi EE, Nichols BL, Rose DR.
    J Mol Biol; 2008 Jan 18; 375(3):782-92. PubMed ID: 18036614
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