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Journal Abstract Search

102 related items for PubMed ID: 2099980

  • 1. [Hirudin inhibition of human thrombin activity].
    Ascenzi P, Bolognesi M, Coletta M, Menegatti E, Amiconi G.
    Medicina (Firenze); 1990; 10(4):391-2. PubMed ID: 2099980
    [Abstract] [Full Text] [Related]

  • 2. Differential activation and inhibition of human platelet thrombin receptors by structurally distinct alpha-, beta- and gamma-thrombin.
    Soslau G, Goldenberg SJ, Class R, Jameson B.
    Platelets; 2004 May; 15(3):155-66. PubMed ID: 15203717
    [Abstract] [Full Text] [Related]

  • 3. Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
    Nardini M, Pesce A, Rizzi M, Casale E, Ferraccioli R, Balliano G, Milla P, Ascenzi P, Bolognesi M.
    J Mol Biol; 1996 May 24; 258(5):851-9. PubMed ID: 8637015
    [Abstract] [Full Text] [Related]

  • 4. Effects of hirudin (thrombin specific inhibitor) in zebrafish embryos: a developmental role for thrombin.
    Jagadeeswaran P, Liu YC, Eddy CA.
    Blood Cells Mol Dis; 1997 Dec 24; 23(3):410-4. PubMed ID: 9446755
    [Abstract] [Full Text] [Related]

  • 5. Molecular dynamics simulations of thrombin inhibitors at the S' subsites of thrombin.
    Yue SY, Konishi Y.
    Drug Des Discov; 1994 Jul 24; 12(1):1-17. PubMed ID: 7578804
    [Abstract] [Full Text] [Related]

  • 6. Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.
    De Simone G, Lombardi A, Galdiero S, Nastri F, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V.
    Protein Sci; 1998 Feb 24; 7(2):243-53. PubMed ID: 9521099
    [Abstract] [Full Text] [Related]

  • 7. CX-397, a novel recombinant hirudin analog having a hybrid sequence of hirudin variants-1 and -3.
    Komatsu Y, Misawa S, Sukesada A, Ohba Y, Hayashi H.
    Biochem Biophys Res Commun; 1993 Oct 29; 196(2):773-9. PubMed ID: 8240353
    [Abstract] [Full Text] [Related]

  • 8. pH dependence of the interaction of hirudin with thrombin.
    Betz A, Hofsteenge J, Stone SR.
    Biochemistry; 1992 Feb 04; 31(4):1168-72. PubMed ID: 1734964
    [Abstract] [Full Text] [Related]

  • 9. The inhibitory effect of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, compared with enoxaparin and r-hirudin on ex vivo thrombin generation in human plasma.
    Boström SL, Hansson GF, Sarich TC, Wolzt M.
    Thromb Res; 2004 Feb 04; 113(1):85-91. PubMed ID: 15081569
    [Abstract] [Full Text] [Related]

  • 10. Antithrombin effects of native and recombinant hirudins.
    Markwardt F, Stürzebecher J, Glusa E.
    Biomed Biochim Acta; 1990 Feb 04; 49(5):399-404. PubMed ID: 2271010
    [Abstract] [Full Text] [Related]

  • 11. [Inducing conformational changes in thrombin by ligands as a way of regulating its activity].
    Gershkovich AA.
    Biokhimiia; 1996 Jul 04; 61(7):1139-51. PubMed ID: 9035728
    [Abstract] [Full Text] [Related]

  • 12. Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety.
    Malikayil JA, Burkhart JP, Schreuder HA, Broersma RJ, Tardif C, Kutcher LW, Mehdi S, Schatzman GL, Neises B, Peet NP.
    Biochemistry; 1997 Feb 04; 36(5):1034-40. PubMed ID: 9033393
    [Abstract] [Full Text] [Related]

  • 13. Bothrojaracin: a potent two-site-directed thrombin inhibitor.
    Arocas V, Zingali RB, Guillin MC, Bon C, Jandrot-Perrus M.
    Biochemistry; 1996 Jul 16; 35(28):9083-9. PubMed ID: 8703912
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and characterization of more potent analogues of hirudin fragment 1-47 containing non-natural amino acids.
    De Filippis V, Quarzago D, Vindigni A, Di Cera E, Fontana A.
    Biochemistry; 1998 Sep 29; 37(39):13507-15. PubMed ID: 9753436
    [Abstract] [Full Text] [Related]

  • 15. Effects of site specific amino acid exchanges in hirudin on the thrombin-hirudin interaction.
    Köhler S, Dodt J.
    Folia Haematol Int Mag Klin Morphol Blutforsch; 1988 Sep 29; 115(1-2):24-9. PubMed ID: 2459027
    [Abstract] [Full Text] [Related]

  • 16. Surface modification with PEG and hirudin for protein resistance and thrombin neutralization in blood contact.
    Alibeik S, Zhu S, Brash JL.
    Colloids Surf B Biointerfaces; 2010 Dec 01; 81(2):389-96. PubMed ID: 20709502
    [Abstract] [Full Text] [Related]

  • 17. Binding of hirudin to human alpha, beta and gamma-thrombin. A comparative kinetic and thermodynamic study.
    Ascenzi P, Amiconi G, Coletta M, Lupidi G, Menegatti E, Onesti S, Bolognesi M.
    J Mol Biol; 1992 May 05; 225(1):177-84. PubMed ID: 1374801
    [Abstract] [Full Text] [Related]

  • 18. The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop.
    Dekker RJ, Eichinger A, Stoop AA, Bode W, Pannekoek H, Horrevoets AJ.
    J Mol Biol; 1999 Oct 29; 293(3):613-27. PubMed ID: 10543954
    [Abstract] [Full Text] [Related]

  • 19. Recombinant hirudin: kinetic mechanism for the inhibition of human thrombin.
    Stone SR, Hofsteenge J.
    Protein Eng; 1991 Feb 29; 4(3):295-300. PubMed ID: 1857714
    [Abstract] [Full Text] [Related]

  • 20. [Coagulation inhibition caused by selective thrombin blockade with hirudin].
    Klöss T, Lorenz W, Meyer U, Mittmann U, Neugebauer E, Saggau WW.
    Chir Forum Exp Klin Forsch; 1978 Feb 29; (1978):143-8. PubMed ID: 752579
    [Abstract] [Full Text] [Related]

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