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Journal Abstract Search

249 related items for PubMed ID: 21030914

  • 1. Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for their antioxidant activity.
    Sausen de Freitas A, de Souza Prestes A, Wagner C, Haigert Sudati J, Alves D, Oliveira Porciúncula L, Kade IJ, Teixeira Rocha JB.
    Molecules; 2010 Oct 28; 15(11):7699-714. PubMed ID: 21030914
    [Abstract] [Full Text] [Related]

  • 2. Diphenyl diselenide and analogs are substrates of cerebral rat thioredoxin reductase: a pathway for their neuroprotective effects.
    de Freitas AS, Rocha JB.
    Neurosci Lett; 2011 Sep 26; 503(1):1-5. PubMed ID: 21839146
    [Abstract] [Full Text] [Related]

  • 3. Diphenyl diselenide protects against methylmercury-induced inhibition of thioredoxin reductase and glutathione peroxidase in human neuroblastoma cells: a comparison with ebselen.
    Meinerz DF, Branco V, Aschner M, Carvalho C, Rocha JBT.
    J Appl Toxicol; 2017 Sep 26; 37(9):1073-1081. PubMed ID: 28383113
    [Abstract] [Full Text] [Related]

  • 4. Diselenoamino acid derivatives as GPx mimics and as substrates of TrxR: in vitro and in silico studies.
    Sudati JH, Nogara PA, Saraiva RA, Wagner C, Alberto EE, Braga AL, Fachinetto R, Piquini PC, Rocha JBT.
    Org Biomol Chem; 2018 May 23; 16(20):3777-3787. PubMed ID: 29737350
    [Abstract] [Full Text] [Related]

  • 5. A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase.
    Zhao R, Holmgren A.
    J Biol Chem; 2002 Oct 18; 277(42):39456-62. PubMed ID: 12177067
    [Abstract] [Full Text] [Related]

  • 6. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant.
    Zhao R, Masayasu H, Holmgren A.
    Proc Natl Acad Sci U S A; 2002 Jun 25; 99(13):8579-84. PubMed ID: 12070343
    [Abstract] [Full Text] [Related]

  • 7. Selenocysteine in mammalian thioredoxin reductase and application of ebselen as a therapeutic.
    Ren X, Zou L, Lu J, Holmgren A.
    Free Radic Biol Med; 2018 Nov 01; 127():238-247. PubMed ID: 29807162
    [Abstract] [Full Text] [Related]

  • 8. Ebselen: a thioredoxin reductase-dependent catalyst for alpha-tocopherol quinone reduction.
    Fang J, Zhong L, Zhao R, Holmgren A.
    Toxicol Appl Pharmacol; 2005 Sep 01; 207(2 Suppl):103-9. PubMed ID: 15979675
    [Abstract] [Full Text] [Related]

  • 9. Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice.
    de Freitas AS, Funck VR, Rotta Mdos S, Bohrer D, Mörschbächer V, Puntel RL, Nogueira CW, Farina M, Aschner M, Rocha JB.
    Brain Res Bull; 2009 Apr 06; 79(1):77-84. PubMed ID: 19047014
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of new nitrogen-containing diselenides.
    Nascimento V, Ferreira NL, Canto RF, Schott KL, Waczuk EP, Sancineto L, Santi C, Rocha JB, Braga AL.
    Eur J Med Chem; 2014 Nov 24; 87():131-9. PubMed ID: 25244678
    [Abstract] [Full Text] [Related]

  • 11. In vitro evaluation of glutathione peroxidase (GPx)-like activity and antioxidant properties of some Ebselen analogues.
    Mouithys-Mickalad Mareque A, Faez JM, Chistiaens L, Kohnen S, Deby C, Hoebeke M, Lamy M, Deby-Dupont G.
    Redox Rep; 2004 Nov 24; 9(2):81-7. PubMed ID: 15231062
    [Abstract] [Full Text] [Related]

  • 12. Ebselen is a dehydroascorbate reductase mimic, facilitating the recycling of ascorbate via mammalian thioredoxin systems.
    Zhao R, Holmgren A.
    Antioxid Redox Signal; 2004 Feb 24; 6(1):99-104. PubMed ID: 14713340
    [Abstract] [Full Text] [Related]

  • 13. 2,2'-dipyridyl diselenide is a better antioxidant than other disubstituted diaryl diselenides.
    Luchese C, Brandão R, Acker CI, Nogueira CW.
    Mol Cell Biochem; 2012 Aug 24; 367(1-2):153-63. PubMed ID: 22544521
    [Abstract] [Full Text] [Related]

  • 14. Diphenyl diselenide modulates gene expression of antioxidant enzymes in the cerebral cortex, hippocampus and striatum of female hypothyroid rats.
    Roseni Mundstock Dias G, Medeiros Golombieski R, de Lima Portella R, Pires do Amaral G, Antunes Soares F, Teixeira da Rocha JB, Wayne Nogueira C, Vargas Barbosa N.
    Neuroendocrinology; 2014 Aug 24; 100(1):45-59. PubMed ID: 25012258
    [Abstract] [Full Text] [Related]

  • 15. Disubstituted diaryl diselenides as potential atheroprotective compounds: Involvement of TrxR and GPx-like systems.
    Straliotto MR, de Oliveira J, Mancini G, Bainy AC, Latini A, Deobald AM, Rocha JB, de Bem AF.
    Eur J Pharm Sci; 2013 Mar 12; 48(4-5):717-25. PubMed ID: 23348152
    [Abstract] [Full Text] [Related]

  • 16. Altered pH homeostasis modulates the glutathione peroxidase mimics and other antioxidant properties of diphenyl diselenide.
    Ogunmoyole T, Rocha JB, Okoronkwo AE, Kade IJ.
    Chem Biol Interact; 2009 Dec 10; 182(2-3):106-11. PubMed ID: 19737547
    [Abstract] [Full Text] [Related]

  • 17. In vitro glutathione peroxidase mimicry of ebselen is linked to its oxidation of critical thiols on key cerebral suphydryl proteins - A novel component of its GPx-mimic antioxidant mechanism emerging from its thiol-modulated toxicology and pharmacology.
    Kade IJ, Balogun BD, Rocha JB.
    Chem Biol Interact; 2013 Oct 25; 206(1):27-36. PubMed ID: 23933410
    [Abstract] [Full Text] [Related]

  • 18. A bis-cyclodextrin diselenide with glutathione peroxidase-like activity.
    Liu J, Luo G, Ren X, Mu Y, Bai Y, Shen J.
    Biochim Biophys Acta; 2000 Sep 29; 1481(2):222-8. PubMed ID: 11018712
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione.
    Lu J, Vlamis-Gardikas A, Kandasamy K, Zhao R, Gustafsson TN, Engstrand L, Hoffner S, Engman L, Holmgren A.
    FASEB J; 2013 Apr 29; 27(4):1394-403. PubMed ID: 23248236
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of in vitro antioxidant effect of new mono and diselenides.
    Stefanello ST, Prestes AS, Ogunmoyole T, Salman SM, Schwab RS, Brender CR, Dornelles L, Rocha JB, Soares FA.
    Toxicol In Vitro; 2013 Aug 29; 27(5):1433-9. PubMed ID: 23499633
    [Abstract] [Full Text] [Related]

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