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Journal Abstract Search


79 related items for PubMed ID: 21036702

  • 1. Synergistic effects of topoisomerase I inhibitor, SN38, on Fas-mediated apoptosis.
    Cao Y, Jin ZX, Tong XP, Yue S, Sakai T, Kawanami T, Sawaki T, Miki M, Iwao H, Nakajima A, Masaki Y, Fukushima Y, Fujita Y, Nakajima H, Okazaki T, Umehara H.
    Anticancer Res; 2010 Oct; 30(10):3911-7. PubMed ID: 21036702
    [Abstract] [Full Text] [Related]

  • 2. Proteasomal degradation of topoisomerase I is preceded by c-Jun NH2-terminal kinase activation, Fas up-regulation, and poly(ADP-ribose) polymerase cleavage in SN38-mediated cytotoxicity against multiple myeloma.
    Catley L, Tai YT, Shringarpure R, Burger R, Son MT, Podar K, Tassone P, Chauhan D, Hideshima T, Denis L, Richardson P, Munshi NC, Anderson KC.
    Cancer Res; 2004 Dec 01; 64(23):8746-53. PubMed ID: 15574786
    [Abstract] [Full Text] [Related]

  • 3. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.
    Ray S, Shyam S, Fraizer GC, Almasan A.
    Mol Cancer Ther; 2007 Apr 01; 6(4):1368-78. PubMed ID: 17431115
    [Abstract] [Full Text] [Related]

  • 4. Topoisomerase inhibitor coralyne photosensitizes DNA, leading to elicitation of Chk2-dependent S-phase checkpoint and p53-independent apoptosis in cancer cells.
    Patro BS, Maity B, Chattopadhyay S.
    Antioxid Redox Signal; 2010 Apr 15; 12(8):945-60. PubMed ID: 19922265
    [Abstract] [Full Text] [Related]

  • 5. 90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
    Tse AN, Sheikh TN, Alan H, Chou TC, Schwartz GK.
    Mol Pharmacol; 2009 Jan 15; 75(1):124-33. PubMed ID: 18820127
    [Abstract] [Full Text] [Related]

  • 6. Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.
    Hayward RL, Macpherson JS, Cummings J, Monia BP, Smyth JF, Jodrell DI.
    Clin Cancer Res; 2003 Jul 15; 9(7):2856-65. PubMed ID: 12855666
    [Abstract] [Full Text] [Related]

  • 7. Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition.
    Wang Z, Wang M, Kar S, Carr BI.
    J Cell Physiol; 2009 Oct 15; 221(1):213-20. PubMed ID: 19530246
    [Abstract] [Full Text] [Related]

  • 8. Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis.
    Wang Y, Wang H, Zhang W, Shao C, Xu P, Shi CH, Shi JG, Li YM, Fu Q, Xue W, Lei YH, Gao JY, Wang JY, Gao XP, Li JQ, Yuan JL, Zhang YT.
    PLoS One; 2013 Oct 15; 8(1):e50175. PubMed ID: 23365634
    [Abstract] [Full Text] [Related]

  • 9. Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis.
    Teoh N, Pyakurel P, Dan YY, Swisshelm K, Hou J, Mitchell C, Fausto N, Gu Y, Farrell G.
    Gastroenterology; 2010 Mar 15; 138(3):1155-65.e1-2. PubMed ID: 19919837
    [Abstract] [Full Text] [Related]

  • 10. PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins.
    Zuco V, De Cesare M, Zaffaroni N, Lanzi C, Cassinelli G.
    Oncotarget; 2015 Apr 20; 6(11):8736-49. PubMed ID: 25826089
    [Abstract] [Full Text] [Related]

  • 11. Assessment of ATM phosphorylation on Ser-1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser-139-histone H2AX phosphorylation, cell cycle phase, and apoptosis.
    Kurose A, Tanaka T, Huang X, Halicka HD, Traganos F, Dai W, Darzynkiewicz Z.
    Cytometry A; 2005 Nov 20; 68(1):1-9. PubMed ID: 16184611
    [Abstract] [Full Text] [Related]

  • 12. Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
    Wang H, Wang X, Zhou XY, Chen DJ, Li GC, Iliakis G, Wang Y.
    Cancer Res; 2002 May 01; 62(9):2483-7. PubMed ID: 11980637
    [Abstract] [Full Text] [Related]

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  • 14. Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner.
    Amantini C, Ballarini P, Caprodossi S, Nabissi M, Morelli MB, Lucciarini R, Cardarelli MA, Mammana G, Santoni G.
    Carcinogenesis; 2009 Aug 01; 30(8):1320-9. PubMed ID: 19502594
    [Abstract] [Full Text] [Related]

  • 15. Ionizing radiation can induce GSK-3beta phosphorylation and NF-kappaB transcriptional transactivation in ATM-deficient fibroblasts.
    Kwon O, Kim KA, He L, Kim SO, Kim MS, Cha EY, Yoon BD, Sok DE, Jung M, Ahn JS, Kim BY.
    Cell Signal; 2008 Apr 01; 20(4):602-12. PubMed ID: 18243662
    [Abstract] [Full Text] [Related]

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  • 17. Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling.
    Goldstein M, Roos WP, Kaina B.
    Toxicol Appl Pharmacol; 2008 May 15; 229(1):20-32. PubMed ID: 18289623
    [Abstract] [Full Text] [Related]

  • 18. [Experimental study of effect of epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in combination with irinotecan].
    Xu JM, Li YM, Wang Y, Zhao CH, Yuan SJ, Yang WW, Li ZQ, Han Y, Azzariti A, Paradiso A.
    Zhonghua Zhong Liu Za Zhi; 2006 Aug 15; 28(8):578-82. PubMed ID: 17236550
    [Abstract] [Full Text] [Related]

  • 19. Sensitization of glioma cells to Fas-dependent apoptosis by chemotherapy-induced oxidative stress.
    Xia S, Rosen EM, Laterra J.
    Cancer Res; 2005 Jun 15; 65(12):5248-55. PubMed ID: 15958570
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
    Uddin S, Hussain AR, Al-Hussein KA, Manogaran PS, Wickrema A, Gutierrez MI, Bhatia KG.
    Clin Cancer Res; 2005 Apr 15; 11(8):3102-8. PubMed ID: 15837766
    [Abstract] [Full Text] [Related]


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