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Journal Abstract Search

407 related items for PubMed ID: 21038414

  • 1. Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.
    Denk GU, Maitz S, Wimmer R, Rust C, Invernizzi P, Ferdinandusse S, Kulik W, Fuchsbichler A, Fickert P, Trauner M, Hofmann AF, Beuers U.
    Hepatology; 2010 Nov; 52(5):1758-68. PubMed ID: 21038414
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  • 2. Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver.
    Wimmer R, Hohenester S, Pusl T, Denk GU, Rust C, Beuers U.
    Gut; 2008 Oct; 57(10):1448-54. PubMed ID: 18583398
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  • 3. Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.
    Beuers U, Bilzer M, Chittattu A, Kullak-Ublick GA, Keppler D, Paumgartner G, Dombrowski F.
    Hepatology; 2001 May; 33(5):1206-16. PubMed ID: 11343250
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  • 4. Tauroursodeoxycholic acid reduces bile acid-induced apoptosis by modulation of AP-1.
    Pusl T, Vennegeerts T, Wimmer R, Denk GU, Beuers U, Rust C.
    Biochem Biophys Res Commun; 2008 Feb 29; 367(1):208-12. PubMed ID: 18164257
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  • 5. Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver.
    Denk GU, Hohenester S, Wimmer R, Böhland C, Rust C, Beuers U.
    Hepatol Res; 2008 Jul 29; 38(7):717-26. PubMed ID: 18328068
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  • 6. Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets.
    Beuers U, Denk GU, Soroka CJ, Wimmer R, Rust C, Paumgartner G, Boyer JL.
    J Biol Chem; 2003 May 16; 278(20):17810-8. PubMed ID: 12626520
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  • 11. Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis.
    Beuers U.
    Nat Clin Pract Gastroenterol Hepatol; 2006 Jun 16; 3(6):318-28. PubMed ID: 16741551
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  • 14. Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
    Halilbasic E, Fiorotto R, Fickert P, Marschall HU, Moustafa T, Spirli C, Fuchsbichler A, Gumhold J, Silbert D, Zatloukal K, Langner C, Maitra U, Denk H, Hofmann AF, Strazzabosco M, Trauner M.
    Hepatology; 2009 Jun 16; 49(6):1972-81. PubMed ID: 19475687
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  • 15. Novel biotransformation and physiological properties of norursodeoxycholic acid in humans.
    Hofmann AF, Zakko SF, Lira M, Clerici C, Hagey LR, Lambert KK, Steinbach JH, Schteingart CD, Olinga P, Groothuis GM.
    Hepatology; 2005 Dec 16; 42(6):1391-8. PubMed ID: 16317695
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  • 18. Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.
    Trauner M, Fickert P, Halilbasic E, Moustafa T.
    Wien Med Wochenschr; 2008 Dec 16; 158(19-20):542-8. PubMed ID: 18998069
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  • 19. norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
    Fickert P, Hirschfield GM, Denk G, Marschall HU, Altorjay I, Färkkilä M, Schramm C, Spengler U, Chapman R, Bergquist A, Schrumpf E, Nevens F, Trivedi P, Reiter FP, Tornai I, Halilbasic E, Greinwald R, Pröls M, Manns MP, Trauner M, European PSC norUDCA Study Group.
    J Hepatol; 2017 Sep 16; 67(3):549-558. PubMed ID: 28529147
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