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662 related items for PubMed ID: 21040406

  • 1. Sulfatase 2 protects hepatocellular carcinoma cells against apoptosis induced by the PI3K inhibitor LY294002 and ERK and JNK kinase inhibitors.
    Lai JP, Sandhu DS, Yu C, Moser CD, Hu C, Shire AM, Aderca I, Murphy LM, Adjei AA, Sanderson S, Roberts LR.
    Liver Int; 2010 Nov; 30(10):1522-8. PubMed ID: 21040406
    [Abstract] [Full Text] [Related]

  • 2. The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation.
    Lai JP, Oseini AM, Moser CD, Yu C, Elsawa SF, Hu C, Nakamura I, Han T, Aderca I, Isomoto H, Garrity-Park MM, Shire AM, Li J, Sanderson SO, Adjei AA, Fernandez-Zapico ME, Roberts LR.
    Hepatology; 2010 Nov; 52(5):1680-9. PubMed ID: 20725905
    [Abstract] [Full Text] [Related]

  • 3. Synergistic growth inhibition by acyclic retinoid and phosphatidylinositol 3-kinase inhibitor in human hepatoma cells.
    Baba A, Shimizu M, Ohno T, Shirakami Y, Kubota M, Kochi T, Terakura D, Tsurumi H, Moriwaki H.
    BMC Cancer; 2013 Oct 08; 13():465. PubMed ID: 24103747
    [Abstract] [Full Text] [Related]

  • 4. Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
    Wang J, Liu X, Zheng H, Liu Q, Zhang H, Wang X, Shen T, Wang S, Ren D.
    Chem Biol Interact; 2020 Nov 01; 331():109279. PubMed ID: 33035517
    [Abstract] [Full Text] [Related]

  • 5. Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
    Lai JP, Sandhu DS, Yu C, Han T, Moser CD, Jackson KK, Guerrero RB, Aderca I, Isomoto H, Garrity-Park MM, Zou H, Shire AM, Nagorney DM, Sanderson SO, Adjei AA, Lee JS, Thorgeirsson SS, Roberts LR.
    Hepatology; 2008 Apr 01; 47(4):1211-22. PubMed ID: 18318435
    [Abstract] [Full Text] [Related]

  • 6. The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling.
    Zheng X, Gai X, Han S, Moser CD, Hu C, Shire AM, Floyd RA, Roberts LR.
    Genes Chromosomes Cancer; 2013 Mar 01; 52(3):225-36. PubMed ID: 23109092
    [Abstract] [Full Text] [Related]

  • 7. MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways.
    Bao L, Yan Y, Xu C, Ji W, Shen S, Xu G, Zeng Y, Sun B, Qian H, Chen L, Wu M, Su C, Chen J.
    Cancer Lett; 2013 Sep 01; 337(2):226-36. PubMed ID: 23684551
    [Abstract] [Full Text] [Related]

  • 8. Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.
    Lai JP, Thompson JR, Sandhu DS, Roberts LR.
    Future Oncol; 2008 Dec 01; 4(6):803-14. PubMed ID: 19086847
    [Abstract] [Full Text] [Related]

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  • 10. Erinacine Facilitates the Opening of the Mitochondrial Permeability Transition Pore Through the Inhibition of the PI3K/ Akt/GSK-3β Signaling Pathway in Human Hepatocellular Carcinoma.
    Zhou LJ, Mo YB, Bu X, Wang JJ, Bai J, Zhang JW, Cheng AB, Ma JH, Wang YW, Xie YX.
    Cell Physiol Biochem; 2018 Dec 01; 50(3):851-867. PubMed ID: 30355923
    [Abstract] [Full Text] [Related]

  • 11. [Combined inhibition of PI3K and MEK has synergistic inhibitory effect on the proliferation of cisplatin-resistant ovarian cancer cells].
    Liu Y, Chen X, Luo Z.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2014 Jun 01; 30(6):592-6. PubMed ID: 24909280
    [Abstract] [Full Text] [Related]

  • 12. Simultaneously targeting Bcl-2 and Akt pathways reverses resistance of nasopharyngeal carcinoma to TRAIL synergistically.
    Li SS, Tang QL, Wang SH, Chen YH, Liu JJ, Yang XM.
    Tumori; 2011 Jun 01; 97(6):762-70. PubMed ID: 22322844
    [Abstract] [Full Text] [Related]

  • 13. Single Agent and Synergistic Activity of the "First-in-Class" Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma.
    Singh AR, Joshi S, Burgoyne AM, Sicklick JK, Ikeda S, Kono Y, Garlich JR, Morales GA, Durden DL.
    Mol Cancer Ther; 2016 Nov 01; 15(11):2553-2562. PubMed ID: 27496136
    [Abstract] [Full Text] [Related]

  • 14. Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.
    Liao YJ, Bai HY, Li ZH, Zou J, Chen JW, Zheng F, Zhang JX, Mai SJ, Zeng MS, Sun HD, Pu JX, Xie D.
    Cell Death Dis; 2014 Mar 20; 5(3):e1137. PubMed ID: 24651440
    [Abstract] [Full Text] [Related]

  • 15. PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells.
    Jeong SJ, Dasgupta A, Jung KJ, Um JH, Burke A, Park HU, Brady JN.
    Virology; 2008 Jan 20; 370(2):264-72. PubMed ID: 17931677
    [Abstract] [Full Text] [Related]

  • 16. Torin2 overcomes sorafenib resistance via suppressing mTORC2-AKT-BAD pathway in hepatocellular carcinoma cells.
    Hu YT, Shu ZY, Jiang JH, Xie QF, Zheng SS.
    Hepatobiliary Pancreat Dis Int; 2020 Dec 20; 19(6):547-554. PubMed ID: 33051131
    [Abstract] [Full Text] [Related]

  • 17. Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal model.
    Xu G, Ji W, Su Y, Xu Y, Yan Y, Shen S, Li X, Sun B, Qian H, Chen L, Fu X, Wu M, Su C.
    Oncotarget; 2014 Jul 15; 5(13):5029-39. PubMed ID: 24970807
    [Abstract] [Full Text] [Related]

  • 18. Induction of apoptosis in human lung carcinoma cells by the water extract of Panax notoginseng is associated with the activation of caspase-3 through downregulation of Akt.
    Park SC, Yoo HS, Park C, Cho CK, Kim GY, Kim WJ, Lee YW, Choi YH.
    Int J Oncol; 2009 Jul 15; 35(1):121-7. PubMed ID: 19513559
    [Abstract] [Full Text] [Related]

  • 19. Induction of Bim expression contributes to the antitumor synergy between sorafenib and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor CI-1040 in hepatocellular carcinoma.
    Ou DL, Shen YC, Liang JD, Liou JY, Yu SL, Fan HH, Wang DS, Lu YS, Hsu C, Cheng AL.
    Clin Cancer Res; 2009 Sep 15; 15(18):5820-8. PubMed ID: 19737956
    [Abstract] [Full Text] [Related]

  • 20. Docetaxel promotes cell apoptosis and decreases SOX2 expression in CD133‑expressing hepatocellular carcinoma stem cells by suppressing the PI3K/AKT signaling pathway.
    Zhang X, Shao J, Li X, Cui L, Tan Z.
    Oncol Rep; 2019 Feb 15; 41(2):1067-1074. PubMed ID: 30483804
    [Abstract] [Full Text] [Related]

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