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Journal Abstract Search

634 related items for PubMed ID: 2105156

  • 1. Biotransformation of N,N',N''-triethylenethiophosphoramide: oxidative desulfuration to yield N,N',N''-triethylenephosphoramide associated with suicide inactivation of a phenobarbital-inducible hepatic P-450 monooxygenase.
    Ng SF, Waxman DJ.
    Cancer Res; 1990 Feb 01; 50(3):464-71. PubMed ID: 2105156
    [Abstract] [Full Text] [Related]

  • 2. N,N',N''-triethylenethiophosphoramide (thio-TEPA) oxygenation by constitutive hepatic P450 enzymes and modulation of drug metabolism and clearance in vivo by P450-inducing agents.
    Ng SF, Waxman DJ.
    Cancer Res; 1991 May 01; 51(9):2340-5. PubMed ID: 1707751
    [Abstract] [Full Text] [Related]

  • 3. Interaction of N,N',N''-triethylenethiophosphoramide and N,N',N''-triethylenephosphoramide with cellular DNA.
    Cohen NA, Egorin MJ, Snyder SW, Ashar B, Wietharn BE, Pan SS, Ross DD, Hilton J.
    Cancer Res; 1991 Aug 15; 51(16):4360-6. PubMed ID: 1714342
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of oxidative drug metabolism by orphenadrine: in vitro and in vivo evidence for isozyme-specific complexation of cytochrome P-450 and inhibition kinetics.
    Reidy GF, Mehta I, Murray M.
    Mol Pharmacol; 1989 May 15; 35(5):736-43. PubMed ID: 2725477
    [Abstract] [Full Text] [Related]

  • 5. Modulation of thiotepa antitumor activity in vivo by alteration of liver cytochrome P450-catalyzed drug metabolism.
    Chang TK, Chen G, Waxman DJ.
    J Pharmacol Exp Ther; 1995 Jul 15; 274(1):270-5. PubMed ID: 7616408
    [Abstract] [Full Text] [Related]

  • 6. In vitro formation of an inhibitory complex between an isosafrole metabolite and rat hepatic cytochrome P-450 PB-B.
    Murray M, Reidy GF.
    Drug Metab Dispos; 1989 Jul 15; 17(4):449-54. PubMed ID: 2571488
    [Abstract] [Full Text] [Related]

  • 7. Oxidative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalysts of drug activation.
    Clarke L, Waxman DJ.
    Cancer Res; 1989 May 01; 49(9):2344-50. PubMed ID: 2706622
    [Abstract] [Full Text] [Related]

  • 8. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D.
    Drug Metab Dispos; 1993 May 01; 21(4):645-56. PubMed ID: 8104124
    [Abstract] [Full Text] [Related]

  • 9. Rat liver cytochrome P450 metabolism of N-acetylbenzidine and N,N'-diacetylbenzidine.
    Lakshmi VM, Zenser TV, Davis BB.
    Drug Metab Dispos; 1997 Apr 01; 25(4):481-8. PubMed ID: 9107548
    [Abstract] [Full Text] [Related]

  • 10. The role of cytochromes P-450 and flavin-containing monooxygenase in the metabolism of (S)-nicotine by rabbit lung.
    Williams DE, Shigenaga MK, Castagnoli N.
    Drug Metab Dispos; 1990 Apr 01; 18(4):418-28. PubMed ID: 1976062
    [Abstract] [Full Text] [Related]

  • 11. Major isozymes of rat liver microsomal cytochrome P-450 involved in the N-oxidation of N-isopropyl-alpha-(2-methylazo)-p-toluamide, the azo derivative of procarbazine.
    Prough RA, Brown MI, Dannan GA, Guengerich FP.
    Cancer Res; 1984 Feb 01; 44(2):543-8. PubMed ID: 6692359
    [Abstract] [Full Text] [Related]

  • 12. Evidence for enzymatic activation and oxygen involvement in cytotoxicity and antitumor activity of N,N',N''-triethylenethiophosphoramide.
    Teicher BA, Waxman DJ, Holden SA, Wang YY, Clarke L, Alvarez Sotomayor E, Jones SM, Frei E.
    Cancer Res; 1989 Sep 15; 49(18):4996-5001. PubMed ID: 2504483
    [Abstract] [Full Text] [Related]

  • 13. Immunochemical detection and quantitation of microsomal cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate:cytochrome P-450 reductase in the rat ventral prostate.
    Haaparanta T, Halpert J, Glaumann H, Gustafsson JA.
    Cancer Res; 1983 Nov 15; 43(11):5131-7. PubMed ID: 6413054
    [Abstract] [Full Text] [Related]

  • 14. Selective inactivation of four rat liver microsomal androstenedione hydroxylases by chloramphenicol analogs.
    Stevens JC, Halpert J.
    Mol Pharmacol; 1988 Jan 15; 33(1):103-10. PubMed ID: 3336347
    [Abstract] [Full Text] [Related]

  • 15. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G, Longo V, Mazzaccaro A, Gervasi PG.
    Chem Res Toxicol; 1996 Jan 15; 9(5):882-90. PubMed ID: 8828925
    [Abstract] [Full Text] [Related]

  • 16. Identification of a reversible component in the in vitro inhibition of rat hepatic cytochrome P450 2B1 by parathion.
    Murray M, Butler AM.
    J Pharmacol Exp Ther; 1995 Feb 15; 272(2):639-44. PubMed ID: 7853177
    [Abstract] [Full Text] [Related]

  • 17. Identification of cytochrome P-450IIB1 as a cocaine-bioactivating isoform in rat hepatic microsomes and in cultured rat hepatocytes.
    Boelsterli UA, Lanzotti A, Göldlin C, Oertle M.
    Drug Metab Dispos; 1992 Feb 15; 20(1):96-101. PubMed ID: 1347004
    [Abstract] [Full Text] [Related]

  • 18. Cytochrome P450 2B1-mediated one-electron reduction of adriamycin: a study with rat liver microsomes and purified enzymes.
    Goeptar AR, Te Koppele JM, Lamme EK, Piqué JM, Vermeulen NP.
    Mol Pharmacol; 1993 Dec 15; 44(6):1267-77. PubMed ID: 8264564
    [Abstract] [Full Text] [Related]

  • 19. Interaction of constitutive and phenobarbital-induced cytochrome P-450 isozymes during the sequential oxidation of benzphetamine. Explanation for the difference in benzphetamine-induced hydrogen peroxide production and 455-nm complex formation in microsomes from untreated and phenobarbital-treated rats.
    Jeffery EH, Mannering GJ.
    Mol Pharmacol; 1983 May 15; 23(3):748-57. PubMed ID: 6865917
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of spironolactone by adrenocortical and hepatic microsomes: relationship to cytochrome P-450 destruction.
    Sherry JH, O'Donnell JP, Flowers L, Lacagnin LB, Colby HD.
    J Pharmacol Exp Ther; 1986 Mar 15; 236(3):675-80. PubMed ID: 3950869
    [Abstract] [Full Text] [Related]

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