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259 related items for PubMed ID: 21057536

  • 1. Absence of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility.
    Preston RS, Philp A, Claessens T, Gijezen L, Dydensborg AB, Dunlop EA, Harper KT, Brinkhuizen T, Menko FH, Davies DM, Land SC, Pause A, Baar K, van Steensel MA, Tee AR.
    Oncogene; 2011 Mar 10; 30(10):1159-73. PubMed ID: 21057536
    [Abstract] [Full Text] [Related]

  • 2. Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.
    Hasumi H, Baba M, Hasumi Y, Furuya M, Yao M.
    Int J Urol; 2016 Mar 10; 23(3):204-10. PubMed ID: 26608100
    [Abstract] [Full Text] [Related]

  • 3. Establishment and characterization of BHD-F59RSVT, an immortalized cell line derived from a renal cell carcinoma in a patient with Birt-Hogg-Dubé syndrome.
    Furuya M, Hasumi H, Baba M, Tanaka R, Iribe Y, Onishi T, Nagashima Y, Nakatani Y, Isono Y, Yao M.
    Lab Invest; 2017 Mar 10; 97(3):343-351. PubMed ID: 27991910
    [Abstract] [Full Text] [Related]

  • 4. Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner.
    Gharbi H, Fabretti F, Bharill P, Rinschen MM, Brinkkötter S, Frommolt P, Burst V, Schermer B, Benzing T, Müller RU.
    Aging Cell; 2013 Aug 10; 12(4):593-603. PubMed ID: 23566034
    [Abstract] [Full Text] [Related]

  • 5. Therapeutic targeting the loss of the birt-hogg-dube suppressor gene.
    Lu X, Wei W, Fenton J, Nahorski MS, Rabai E, Reiman A, Seabra L, Nagy Z, Latif F, Maher ER.
    Mol Cancer Ther; 2011 Jan 10; 10(1):80-9. PubMed ID: 21220493
    [Abstract] [Full Text] [Related]

  • 6. Fluorescent and chromogenic in situ hybridization of CEN17q as a potent useful diagnostic marker for Birt-Hogg-Dubé syndrome-associated chromophobe renal cell carcinomas.
    Kato I, Iribe Y, Nagashima Y, Kuroda N, Tanaka R, Nakatani Y, Hasumi H, Yao M, Furuya M.
    Hum Pathol; 2016 Jun 10; 52():74-82. PubMed ID: 26980015
    [Abstract] [Full Text] [Related]

  • 7. Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt-Hogg-Dubé syndrome.
    Furuya M, Hong SB, Tanaka R, Kuroda N, Nagashima Y, Nagahama K, Suyama T, Yao M, Nakatani Y.
    Cancer Sci; 2015 Mar 10; 106(3):315-23. PubMed ID: 25594584
    [Abstract] [Full Text] [Related]

  • 8. Birt-Hogg-Dubé syndrome: novel FLCN frameshift deletion in daughter and father with renal cell carcinomas.
    Näf E, Laubscher D, Hopfer H, Streit M, Matyas G.
    Fam Cancer; 2016 Jan 10; 15(1):127-32. PubMed ID: 26342594
    [Abstract] [Full Text] [Related]

  • 9. Folliculin deficient renal cancer cells show higher radiosensitivity through autophagic cell death.
    Zhang Q, Si S, Schoen S, Jin XB, Chen J, Wu G.
    J Urol; 2014 Jun 10; 191(6):1880-8. PubMed ID: 24434776
    [Abstract] [Full Text] [Related]

  • 10. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
    [Abstract] [Full Text] [Related]

  • 11. Heterozygous germline FLCN mutation in Birt-Hogg-Dubé syndrome with bilateral renal hybrid oncocytic/chromophobe tumor and unilateral renal chromophobe cell carcinoma: a case report.
    Li J, Liu F, Liu X, Hu Y, Liu Z, Shen Y, Wan J.
    J Cancer Res Clin Oncol; 2023 Jun 16; 149(6):2319-2325. PubMed ID: 36258004
    [Abstract] [Full Text] [Related]

  • 12. Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN).
    Lu X, Boora U, Seabra L, Rabai EM, Fenton J, Reiman A, Nagy Z, Maher ER.
    Oncogene; 2014 Feb 20; 33(8):956-65. PubMed ID: 23416984
    [Abstract] [Full Text] [Related]

  • 13. Immunohistochemical characterization of renal tumors in patients with Birt-Hogg-Dubé syndrome.
    Iribe Y, Kuroda N, Nagashima Y, Yao M, Tanaka R, Gotoda H, Kawakami F, Imamura Y, Nakamura Y, Ando M, Araki A, Matsushima J, Nakatani Y, Furuya M.
    Pathol Int; 2015 Mar 20; 65(3):126-32. PubMed ID: 25597876
    [Abstract] [Full Text] [Related]

  • 14. Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.
    Tee AR, Pause A.
    Fam Cancer; 2013 Sep 20; 12(3):367-72. PubMed ID: 23096221
    [Abstract] [Full Text] [Related]

  • 15. A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.
    Napolitano G, Di Malta C, Esposito A, de Araujo MEG, Pece S, Bertalot G, Matarese M, Benedetti V, Zampelli A, Stasyk T, Siciliano D, Venuta A, Cesana M, Vilardo C, Nusco E, Monfregola J, Calcagnì A, Di Fiore PP, Huber LA, Ballabio A.
    Nature; 2020 Sep 20; 585(7826):597-602. PubMed ID: 32612235
    [Abstract] [Full Text] [Related]

  • 16. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C, Moore JW, Robertson N, Harris AL.
    Cancer Res; 2001 Oct 01; 61(19):7349-55. PubMed ID: 11585776
    [Abstract] [Full Text] [Related]

  • 17. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 18. Renal cell tumour characteristics in patients with the Birt-Hogg-Dubé cancer susceptibility syndrome: a retrospective, multicentre study.
    Benusiglio PR, Giraud S, Deveaux S, Méjean A, Correas JM, Joly D, Timsit MO, Ferlicot S, Verkarre V, Abadie C, Chauveau D, Leroux D, Avril MF, Cordier JF, Richard S, French National Cancer Institute Inherited Predisposition to Kidney Cancer Network.
    Orphanet J Rare Dis; 2014 Oct 29; 9():163. PubMed ID: 25519458
    [Abstract] [Full Text] [Related]

  • 19. Identification and characterization of Birt-Hogg-Dubé associated renal carcinoma.
    Murakami T, Sano F, Huang Y, Komiya A, Baba M, Osada Y, Nagashima Y, Kondo K, Nakaigawa N, Miura T, Kubota Y, Yao M, Kishida T.
    J Pathol; 2007 Apr 29; 211(5):524-531. PubMed ID: 17323425
    [Abstract] [Full Text] [Related]

  • 20. Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene.
    Liu MY, Poellinger L, Walker CL.
    Cancer Res; 2003 May 15; 63(10):2675-80. PubMed ID: 12750296
    [Abstract] [Full Text] [Related]

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