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Journal Abstract Search

193 related items for PubMed ID: 21058916

  • 1. Comparison of intrinsic clearances in human liver microsomes and suspended hepatocytes from the same donor livers: clearance-dependent relationship and implications for prediction of in vivo clearance.
    Foster JA, Houston JB, Hallifax D.
    Xenobiotica; 2011 Feb; 41(2):124-36. PubMed ID: 21058916
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  • 3. Metabolite formation kinetics and intrinsic clearance of phenacetin, tolbutamide, alprazolam, and midazolam in adenoviral cytochrome P450-transfected HepG2 cells and comparison with hepatocytes and in vivo.
    Donato MT, Hallifax D, Picazo L, Castell JV, Houston JB, Gomez-Lechón MJ, Lahoz A.
    Drug Metab Dispos; 2010 Sep; 38(9):1449-55. PubMed ID: 20501911
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  • 4. Substrate depletion approach for determining in vitro metabolic clearance: time dependencies in hepatocyte and microsomal incubations.
    Jones HM, Houston JB.
    Drug Metab Dispos; 2004 Sep; 32(9):973-82. PubMed ID: 15319339
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  • 6. Prediction of drug clearance by glucuronidation from in vitro data: use of combined cytochrome P450 and UDP-glucuronosyltransferase cofactors in alamethicin-activated human liver microsomes.
    Kilford PJ, Stringer R, Sohal B, Houston JB, Galetin A.
    Drug Metab Dispos; 2009 Jan; 37(1):82-9. PubMed ID: 18832476
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  • 10. Rifampin induces the in vitro oxidative metabolism, but not the in vivo clearance of diclofenac in rhesus monkeys.
    Prueksaritanont T, Li C, Tang C, Kuo Y, Strong-Basalyga K, Carr B.
    Drug Metab Dispos; 2006 Nov; 34(11):1806-10. PubMed ID: 16928785
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  • 12. Prediction of human drug clearance by multiple metabolic pathways: integration of hepatic and intestinal microsomal and cytosolic data.
    Cubitt HE, Houston JB, Galetin A.
    Drug Metab Dispos; 2011 May; 39(5):864-73. PubMed ID: 21303923
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  • 20. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.
    Parkinson A, Mudra DR, Johnson C, Dwyer A, Carroll KM.
    Toxicol Appl Pharmacol; 2004 Sep 15; 199(3):193-209. PubMed ID: 15364537
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